Eye diseases in Hollywood movies !

1. Eywood !
By
Ahmed Alsherbeny
MD, CABOphth, MRCSEd Ophth, FRCS Ophth (Glasg), FICO

2. Hoping to walk away with a massive fortune, a trio of thieves
break into the house of a blind man who isn't as helpless as he
seems. That man, who served in the Gulf War, is blind caused by
an explosion during the war.

3. In central Texas in the 1930s, a widow, with two small children, tries to run her
small 40-acre farm with the help of two disparate people. One of them is a blind
boarder, Mr. Will, who lost his sight in the first World War.

4. A blind Vietnam vet, who was blinded during the war. He was trained as a
swordfighter, comes to America and helps to rescue the son of a fellow
soldier.

5. Patients with traumatic ocular injuries
must be evaluated for systemic injuries
as well.

6. After he gets blinded by a German sniper's bullet in 1943, Sergeant Larry
Nevins begins the long and painful road to recovery.

7. MRI should never be performed if
a metallic foreign body is suspected

8. A prep school student needing money agrees to "babysit" a blind
alcoholic man, but the job is not at all what he anticipated.
The reason behind Slade's blindness is also revealed: one of
Slade's relatives, Randy, tells the story about how Slade used to
juggle grenades while drunk. One grenade got away from him and
exploded, causing his blindness

9. Set in 1930s Shanghai, where a blind American diplomat develops a
curious relationship with a young Russian refugee who works odd -- and
sometimes illicit -- jobs to support members of her dead husband's
aristocratic family.
several years ago, he lost his wife and daughter in separate terrorist
bombings. The bombing that killed his child also blinded him

10. The violinist Sydney Wells has been blind since she was five years old,
caused by an accident with firecrackers. She submits to a surgery of
cornea transplantation to recover her vision, and while recovering from
the operation, she realizes that she's having strange visions.

11. Always check the pressure in the
contralateral eye in a patient with
ocular trauma.
Asymmetrically low intraocular pressure
may be an important clue to a potential
ruptured globe.

12. A novelist blinded in a car crash which killed his wife rediscovers his
passion for both life and writing when he embarks on an affair with the
neglected wife of an indicted businessman.

13. A blind woman's relationship with her husband changes when she regains her
sight and discovers disturbing details about themselves.
Blinded since childhood when a hideous car-crash cost her parents and her
eyesight
Gina prepares for a cornea transplant, which will restore the sight in one of her
eyes. The surgery is a success, and Gina embraces her newfound independence

14. After ocular trauma , especially rupture
globe , In follow up visits after primary
repair , careful examination of the
other eye is very important to detect
sympathetic ophthalmitis

15. When a beautiful socialite falls in love with an embittered composer who
is blind, she feigns blindness herself in order to get closer to him.
He lost his sight from another driver's car crash

16. A recently blinded woman due to an auto accident is terrorized by a trio of
thugs while they search for a heroin-stuffed doll they believe is in her
apartment.

17. A big-city cop from L.A. moves to a small-town police force and
immediately finds himself investigating a murder. Using theories rejected
by his colleagues, the cop, John Berlin, meets a young blind woman
named Helena, who he is attracted to. Meanwhile, a serial killer who kills
only blind girls is on the loose and only John knows it.
Helena was blinded at the age of 14 due to car accident

18. October 2014
FRCS Glasgow Problem solving Exam

19. Alexis is a young girl who dreams of becoming a champion figure skater.
One day, while practicing, Alexis falls and hits her head, which causes her
to go blind which threatens to destroy her dreams. After some training,
she is actually capable of competing again, and she goes to the national
competition, with the public unaware she is blind !!!
1978 2010

20. In the English countryside, Sarah Rexton, recently blinded in a horse
riding accident, moves in with her uncle's family and gallantly adjusts to
her new condition, unaware that a killer stalks them.

21. Patients recovering from a traumatic
hyphema are at increased risk for
glaucoma and retinal detachments in
the future. They need ongoing
ophthalmic evaluation for the rest of
their lives.

22. When a high school football star is suddenly stricken with irreversible total
blindness lost his sight due to a sinus infection caused by a rare disease, he
must decide whether to live a safe handicapped life or bravely return to the life
he once knew and the sport he still loves.
condition started with severe headaches and a bacterial meningitis infection. After
being rushed to the hospital, Travis undergoes surgery to remove the infection and
save his life. He comes out of the procedure alive, but he is now blind

23. Remember
The lamina papyracea, which forms part of the medial orbital wall,
is paper-thin and perforated by numerous foramina for nerves and
blood vessels. Orbital cellulitis is therefore frequently secondary to
ethmoidal sinusitis.

24. The true story of Anne Sullivan's struggle to teach the
blind and deaf Helen Keller how to communicate.
At 19 months old, Keller contracted an unknown illness described by
doctors as "an acute congestion of the stomach and the brain", which
might have been scarlet fever or meningitis. The illness left her both deaf
and blind

25. Deafness & the eye
Ushersyndrome
Alportsyndrome
Vogt-Koyanagi-Haradasyndrome
DIDMODsyndrome
Congenitalsyphilis
Sticklersyndrome
Refsumsyndrome
Fredreichataxia
Cogansyndrome
Susacsyndroem
Rubella
Remember: Usher syndrome (AR, genetically heterogeneous)
accounts for about 5% of all cases of profound deafness in children
and about half of all cases of combined deafness and blindness.

26. A blind lawyer by day, vigilante by night. Matt Murdock fights the
crime of New York as Daredevil.
As a child Matt Murdock was blinded by a chemical spill in a freak
accident. Instead of limiting him it gave him superhuman senses
that enabled him to see the world in a unique and powerful way

27. A blind, uneducated white girl is befriended by a black man, who
becomes determined to help her escape her impoverished and abusive
home life by introducing her to the outside world.
Accidentally blinded at the age of five by when her mother threw
chemicals on her while attempting to hit her husband.

28. Immediately irrigate any patient
with a chemical ocular injury from an
alkali or acid, without taking a history
or performing examination

29. The true story of the life and career of the legendary rhythm and blues
musician Ray Charles, from his humble beginnings in the South, where
he went blind at age seven apparently as a result of glaucoma, to his
meteoric rise to stardom during the 1950s and 1960s.

30. Incidence of glaucoma:
1- primary open angle 1:100
2- primary closed angle 1:1000
3- congenital glaucoma 1:10000

31. Congenital glaucoma may masquerade as neonatal conjunctivitis &
Cong NLD obstruction and should always be considered, particularly
in monocular cases
Rt eye shows lacrimation/epiphora as in Cong NLD obstruction
Lt eye shows pink eye and sticky discharge as in neonatal conjunctivitis

32. Progressive enlargement of the corneal
diameter is as important sign of uncontrolled
congenital glaucoma as progressive visual
field loss is in adult glaucoma

33. A light comedy/love story based on the true story of blind musician Tom
Sullivan.
His premature birth caused him to need oxygen treatment while in an
incubator. Though the treatment saved his life, he was given too much
oxygen, which left him permanently blind due to retinopathy of
prematurity.

34. Remember !
Babies born at or before 30–32 weeks
gestational age, or weighing 1500g or
less, should be screened for ROP

35. A post-apocalyptic tale, in which a lone blind man fights his way across
America in order to protect a sacred book that holds the secrets to saving
humankind.
Eli is also blinded like others by The Flash (Strong light due to nuclear
apocalypse), an event which occurred during the Last Great War.

36. Light injury to the eye
(Non-ionizingradiation)
• Microwave (> 12,000 nm):
Cataract
• Infrared (12,000–770 nm):
True exfoliation of lens (glassblower’s cataract)
• Visible light (760–400 nm): (photic damage)
• Mechanical (e.g. photodisruption)
• Thermal (e.g. photocoagulation)
• Photobiochemical (e.g. solar retinopathy, photic retinopathy)
• Ultraviolet (180–390 nm):
Surface epithelial disease, radiation keratitis (Photophthalmia),
pterygium, cataract, Spheroidal degeneration
Remember the importance of filters in all ophthalmic equipments for
safety of both patients and doctors especially laser filters

37. The story of a woman who is slowly losing her sight whilst trying to investigate the
mysterious death of her twin sister.
Julia, who has the same degenerative disease of her killed blind sister. Eye transplant
is performed but failed at the end of the movie
From a medical point of view , you can’t decide if it is a drug related toxicity of already
susceptible eye – not treated with keratoplasty for sure as in the movie – as in
alcohol/methanol/tobacco toxicity or it is just a corneal dystrophy / degeneration although
her cornea was clear all the time !!
Maybe the transplant received is sensor chip for retinal degenerative disease !!

38. A man with a fateful secret embarks on an extraordinary journey of
redemption by forever changing the lives of seven strangers.
In the movie, we meet Ezra who is blind in both eyes due to corneal
opacity and needs keratoplasty

39. Emma, a blind for 20 years due to corneal opacity who had recently undergone a
revolutionary surgery restore her vision in right eye first but initially cause
"vision flashes" that leave her uncertain about what she sees.
She joins with a police detective to track a serial killer after she was an
inadvertent witness to his latest crime.

40. Stromal dystrophies
Marilyn Monroe Always Gets Her Man in LA
City
Macular dystrophy
Mucopolysaccharide
Alcian blue
Granular Dystrophy
Hyaline material
Masson's Trichrome
Lattice Dystrophy
Amyloid
Congo Red

41. Congenital cloudy cornea
" STUMPED "
Sclerocornea
Tears in Descmet's membrane
Uterine infections
Metabolic conditions
Peter’s anomaly
Endothelial dystrophy
Dermoid

42. After being drugged and raped at a party, a young woman contracts what she
thinks is an STD; but, it's actually something much worse.
Due to her infection she developed a rash in her groin. Almost all the entire
movie we didn’t know the causative organism of the symptoms and signs she
was suffering from and a unknown virus was accused but from a medical point
of view , syphilis is likely to be the cause

43. N.B.
Syphilis is often known as the “Great
Imitator”. Ocular syphilis being
particularly challenging to diagnose as
it can mimic any form of uveitis

44. Syphilis must be suspected in any
case of intraocular inflammation
resistant to conventional therapy

45. A blind man since age 3 has an operation to regain his sight at the urging of his
girlfriend and must deal with the changes to his life.
Inspired by the true life story of Shirl Jennings was diagnosed with retinitis
pigmentosa. He visited Dr. Trevor Woodhams to investigate opportunities to
restore his sight. Woodhams suggested surgery to remove his dense cataracts
and to determine the true underlying condition of his retina.

46. Remember !

47. A blind young man (Pine) thinks he finds love with an Indian woman (Jay),
though their relationship is fraught with cultural differences.
Having been blind from birth, he volunteers for a risky experimental
procedure that may restore his sight, having a microchip installed in the
visual cortex of his brain that connects to a camera that would give
him only, at best, fuzzy black and white images.

48. A series of events tests the beliefs of a small isolated countryside village.
Ivy is blind since she was very young

49. Black comedy about a blind man since childhood , Martin, who takes
photographs as "proof" that the world really is as others describe it to
him.

50. A blind American writer with recent and permanent loss of his sight
living in London stumbles upon a criminal conspiracy involving kidnapping and
extortion.

51. Dave is deaf, and Wally is blind. They witness a murder, but it was Dave who was
looking at her, and Wally who was listening.

52. Jace Newfield has a problem. Besides being blind and being the new kid
at school, his problem is that the kids at his new school thinks he's a jerk.
Jace has to find a way to be accepted

53. A molecular biologist and his laboratory partner uncover evidence
that may fundamentally change society as we know it.
As they delve further into the mystery, they start to see data that
challenges the known fact that everyone's eyes / iris pattern are
unique.

54. Remember
All the muscles of the body derived from
mesoderm except Iris muscles delivered from
neural ectoderm

55. Desperate to help her ailing brother, a young woman unknowingly agrees to
compete in a deadly game of "Would You Rather," hosted by a sadistic aristocrat.
In the movie, Lucas' card forces him to slit open his own eye within 30
seconds; he does so and survives.

56. Eyelid reconstruction
Small defects involving less than one-third of the eyelid can usually be
closed directly, provided the surrounding tissue is sufficiently elastic to allow
approximation of the cut edges
Moderate size defects involving up to half of the eyelid may
require a flap (e.g. Tenzel semi-circular) for closure
Large defects involving over half of the eyelid may be closed by one of
the following techniques:
○ Posterior lamellar reconstruction may involve an upper lid free tarsal graft, buccal
mucous membrane or hard palate graft, or a Hughes tarsoconjunctival flap from the
upper lid, which is left attached for 4–6 weeks before transection
○ Anterior lamellar reconstruction may involve skin advancement

57. A city is ravaged by an epidemic of instant white blindness.
Agnosia was mentioned but the movie script denied this hypothesis for sure
From a medical point of view, there’s no such an infective epidemic disease
with sudden bilateral loss of vision in a form of a white blindness not black
then sudden recovery happens !!

58. Survivors of a suspension-bridge collapse (Final Destination 4) learn there's no
way you can cheat death.
the LASIK machine begins to malfunction, overheating, and the button to begin
surgery the laser slices her eye open.

59. After Cesar is drugged with morphine, the scene showed his pupil was dilating
constantly after injection !!! Where’s the pin point pupil ?!

60. Pin point pupil
Morphine & Narcotics
Hypertension medications such as clonidine
Heroin
Horner syndrome
Pontine hemorrhage
Organophosphorus poisoning
Remember: Antidoteof morphine poisoning is naloxone

61. While showing the security measures in the bank we discover that there’s
something called retinoscan which scan the retina of the bank manager to open
the safe, we discover as shown in the figure above that the bank manager has
stage IV macular hole !! 

62. Thank You