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N.B IV !
By
Ahmed Alsherbeny
MD, CABOphth, MRCSEd Ophth, FRCS Ophth (Glasg), FICO
Topiramate is used in the treatment of
migraine and may result in acute angle
closure secondary to swelling of the
ciliary body.
Systemic alpha-blockers (e.g. tamsulosin)
are the main cause of intraocular floppy
iris syndrome when undertaking
phacoemulsification
Monoclonal antibody treatment
(adalimumab/infliximab) has improved the
prognosis in patients with vision-
threatening chronic uveitis
Long-term use of oral aciclovir reduces the
recurrence rate of epithelial and stromal
herpes keratitis. Generalized seizers,
hemiparesis or hemianopia
In a patient with a linear corneal
abrasion, search for a small foreign body
on the tarsal surface of the upper lid.
In a patient with a small lid wound who
has been working with tools, always lift
the lids to check for a small penetrating
injury in the sclera.
Investigate any asymptomatic middle-
aged individual with a prominent episcleral
(sentinel) vessel, as this can be a subtle
sign of ciliary body melanoma
Migraine is the commonest cause of visual
aura with and without headache
Children with intermittent exotropia tend
to close an eye when exposed to bright
light
In a patient with proliferative diabetic
retinopathy and macular oedema, first
treat the oedema then undertake
panretinal photocoagulation
Toxoplasmosis is the most common
identifiable cause for focal retinitis,
which typically causes inflammation
adjacent to a chorioretinal scar
A transient hypopyon in a relatively
white eye is typical of Behçet disease
and JIA-associated uveitis
Pseudoexfoliation glaucoma progresses
more rapidly than primary open-angle
glaucoma and is more likely to result in
significant visual loss
In the event of vitreous loss in cataract
surgery and raised IOP, avoid
prostaglandin drops as this increases the
risk of cystoid macular oedema.
To achieve accurate preoperative
biometry, contact lenses should not be
worn for 1–2 weeks before the
measurements are taken.
In a patient with acute corneal graft
rejection, early intensive treatment greatly
improves the likelihood of reversing the
episode of rejection.
Peripheral ulcerative keratitis is caused by
an infection until proven otherwise. In the
absence of an infection investigate for
systemic autoimmune disease
Vesicles involving the tip or side of
the nose precede the development of
ophthalmic herpes zoster (Hutchinson
sign).
Acanthamoeba infection of the cornea
results in pain that is often severe and
disproportionate to the clinical signs
Herpes simplex is the commonest infectious
cause of corneal disease in developed
countries
Topical drug and preservative toxicity may
cause a failure of corneal re-
epithelialization, which can be confused
with persistent infection
Fluoroquinolone eyedrops have limited
effectivity against Gram-positive organisms
(particularly Streptococcus).
Check thyroid function in patients with
superior limbic keratoconjunctivitis.
In a patient with adult chlamydial
conjunctivitis, other sexually transmitted
infections should be excluded
In dry eye syndrome lissamine green
solution is preferable to 1% rose Bengal
solution as it stains in a similar fashion,
but causes less irritation.
Visual acuity, pupillary responses and
ocular motility are unimpaired, and
proptosis is absent in preseptal cellulitis.
Surgical orbital decompression should be
considered when there is sight-threatening
compressive optic neuropathy in thyroid
eye disease.
To reduce the risk of endophthalmitis
postpone intraocular surgery if there are
any signs of lacrimal drainage system
infection
Chronic canaliculitis should be suspected
in a patient with unilateral mucopurulent
conjunctivitis that is refractory to
conventional treatment.
A congenital dacryocoele should not be
confused with an encephalocoele, which is
characterized by a pulsatile swelling above
the medial canthal ligament.
Involutional ptosis may be confused with
ocular myasthenia gravis because it
frequently gets worse towards the end of
the day.
A capillary haemangioma can be easily and
successfully treated by regular application
of a topical beta-blocker to the affected
lesion.
In a patient with a corneal graft, broken
or loose sutures should be removed as this
reduces the risk of localized
vascularization and graft rejection.
The organisms involved in fistula-related
endopthalmitis tend to be more virulent
than after cataract surgery. Vitreous and
aqueous samples should be obtained
immediately on presentation
Thank You

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N.B IV

  • 1. N.B IV ! By Ahmed Alsherbeny MD, CABOphth, MRCSEd Ophth, FRCS Ophth (Glasg), FICO
  • 2. Topiramate is used in the treatment of migraine and may result in acute angle closure secondary to swelling of the ciliary body.
  • 3. Systemic alpha-blockers (e.g. tamsulosin) are the main cause of intraocular floppy iris syndrome when undertaking phacoemulsification
  • 4. Monoclonal antibody treatment (adalimumab/infliximab) has improved the prognosis in patients with vision- threatening chronic uveitis
  • 5. Long-term use of oral aciclovir reduces the recurrence rate of epithelial and stromal herpes keratitis. Generalized seizers, hemiparesis or hemianopia
  • 6. In a patient with a linear corneal abrasion, search for a small foreign body on the tarsal surface of the upper lid.
  • 7. In a patient with a small lid wound who has been working with tools, always lift the lids to check for a small penetrating injury in the sclera.
  • 8. Investigate any asymptomatic middle- aged individual with a prominent episcleral (sentinel) vessel, as this can be a subtle sign of ciliary body melanoma
  • 9. Migraine is the commonest cause of visual aura with and without headache
  • 10. Children with intermittent exotropia tend to close an eye when exposed to bright light
  • 11. In a patient with proliferative diabetic retinopathy and macular oedema, first treat the oedema then undertake panretinal photocoagulation
  • 12. Toxoplasmosis is the most common identifiable cause for focal retinitis, which typically causes inflammation adjacent to a chorioretinal scar
  • 13. A transient hypopyon in a relatively white eye is typical of Behçet disease and JIA-associated uveitis
  • 14. Pseudoexfoliation glaucoma progresses more rapidly than primary open-angle glaucoma and is more likely to result in significant visual loss
  • 15. In the event of vitreous loss in cataract surgery and raised IOP, avoid prostaglandin drops as this increases the risk of cystoid macular oedema.
  • 16. To achieve accurate preoperative biometry, contact lenses should not be worn for 1–2 weeks before the measurements are taken.
  • 17. In a patient with acute corneal graft rejection, early intensive treatment greatly improves the likelihood of reversing the episode of rejection.
  • 18. Peripheral ulcerative keratitis is caused by an infection until proven otherwise. In the absence of an infection investigate for systemic autoimmune disease
  • 19. Vesicles involving the tip or side of the nose precede the development of ophthalmic herpes zoster (Hutchinson sign).
  • 20. Acanthamoeba infection of the cornea results in pain that is often severe and disproportionate to the clinical signs
  • 21. Herpes simplex is the commonest infectious cause of corneal disease in developed countries
  • 22. Topical drug and preservative toxicity may cause a failure of corneal re- epithelialization, which can be confused with persistent infection
  • 23. Fluoroquinolone eyedrops have limited effectivity against Gram-positive organisms (particularly Streptococcus).
  • 24. Check thyroid function in patients with superior limbic keratoconjunctivitis.
  • 25. In a patient with adult chlamydial conjunctivitis, other sexually transmitted infections should be excluded
  • 26. In dry eye syndrome lissamine green solution is preferable to 1% rose Bengal solution as it stains in a similar fashion, but causes less irritation.
  • 27. Visual acuity, pupillary responses and ocular motility are unimpaired, and proptosis is absent in preseptal cellulitis.
  • 28. Surgical orbital decompression should be considered when there is sight-threatening compressive optic neuropathy in thyroid eye disease.
  • 29. To reduce the risk of endophthalmitis postpone intraocular surgery if there are any signs of lacrimal drainage system infection
  • 30. Chronic canaliculitis should be suspected in a patient with unilateral mucopurulent conjunctivitis that is refractory to conventional treatment.
  • 31. A congenital dacryocoele should not be confused with an encephalocoele, which is characterized by a pulsatile swelling above the medial canthal ligament.
  • 32. Involutional ptosis may be confused with ocular myasthenia gravis because it frequently gets worse towards the end of the day.
  • 33. A capillary haemangioma can be easily and successfully treated by regular application of a topical beta-blocker to the affected lesion.
  • 34. In a patient with a corneal graft, broken or loose sutures should be removed as this reduces the risk of localized vascularization and graft rejection.
  • 35. The organisms involved in fistula-related endopthalmitis tend to be more virulent than after cataract surgery. Vitreous and aqueous samples should be obtained immediately on presentation