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MULTIPLE ALLELES
( BLOOD GROUP)
WHAT ARE ALLELES ?
• Alleles are the gene which code for a pair of
contrasting traits.
• they are the slightly different forms of the
same gene.
MULTIPLE ALLELES
• If there are more than two allele i.e., three
alleles , governing the same character , then
it is called as multiple alleles.
• It is found only when population studies are
made.
ABO Blood Group
• ABO blood group are controlled by the gene
I.
• Gene has three allelic form: IA , IB , i
• Alleles IA and IB produce slightly different
form of the sugar while allele i does not
produce any sugar.
GENOTYPE PHENO
TYPE
TERMINAL
SUGAR OF
ANTIGEN
ANTIGEN
PRESENT
ANTIBODI
ES
PRESENT
RED CELL
TYPE
AGGLUTIN
ATION
TRANSFUS
IN
ACCEPTED
FORM
IAIA or IA i A A-
galactosamine
Antigen-A Anti-B B, AB A,O
IB IB OR IB i B B-
galactosamine
Antigen-B Anti-A A,AB B,O
IA IB AB A-
galactosamine
B-
galactosamine
Antigen-A
Antigen-B
None None A,B,AB
ii O None None Anti-A
Anti-B
A,B ,AB O
THANK YOU

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Multiple alleles

  • 2. WHAT ARE ALLELES ? • Alleles are the gene which code for a pair of contrasting traits. • they are the slightly different forms of the same gene.
  • 3. MULTIPLE ALLELES • If there are more than two allele i.e., three alleles , governing the same character , then it is called as multiple alleles. • It is found only when population studies are made.
  • 4. ABO Blood Group • ABO blood group are controlled by the gene I. • Gene has three allelic form: IA , IB , i • Alleles IA and IB produce slightly different form of the sugar while allele i does not produce any sugar.
  • 5. GENOTYPE PHENO TYPE TERMINAL SUGAR OF ANTIGEN ANTIGEN PRESENT ANTIBODI ES PRESENT RED CELL TYPE AGGLUTIN ATION TRANSFUS IN ACCEPTED FORM IAIA or IA i A A- galactosamine Antigen-A Anti-B B, AB A,O IB IB OR IB i B B- galactosamine Antigen-B Anti-A A,AB B,O IA IB AB A- galactosamine B- galactosamine Antigen-A Antigen-B None None A,B,AB ii O None None Anti-A Anti-B A,B ,AB O