application of nanaocarriers in delivery of biotechnologicals.

1. Application of Nanocarriers in
Delivery of Biotechnologicals
Presented by,
Mr. MEHETRE AKSHAY DILIPRAO
F.Y. M.Pharm (Sem-II)
2016-2017
Shri Bhagwan College of
Pharmacy ,Aurangabad

2.  DEFINATION:-
Nanocarriers are colloidal particulate
system with size between 10-1000nm.
They have been successfully utililzed in
the diagnosis,treatment and monitoring of
various diseases.
NANOCARRIERS

3.  NANOCAPSULE
 NANOPARTICLES
 NANOEMULSION
 NANOSOMES
 DENDRIMERS
 NANOTUBES
 NANOSUSPENSION
classification

4.  DEFINATION:-
Nanocapsule is a nano-
vesicular systems that exhibit a typical
core-shell structure in which the drug is
confined to a reservoir or within a cavity
surrounded by a polymer membrane or
coating.
NANOCAPSULE

5. Fig. 1. Different nanocapsular structures: (a) liquid core, (b) polymer
matrix and (c) active substance in molecular dispersion

6.  In cancer
 Food usage
 Nutraceuticals
 Ethyl alcohol absorption
 Self healing materials
Applications OF NANOCAPSULE

7.  Nanoparticle – any particle that is sized between 1 and 100
nanometers (in terms of diameter)
 The use of nanoparticles
allows one to change the
pharmacokinetic properties
of the drug without
changing the active
compound.
nanoparticles

8.  Nanoparticles for oral delivery of peptides and
proteins-
 Nanoparticles for occular application
 Nanoparticles for pulmonary treatment
 Nanoparticles in treatment of vascular
thrombosis
Applications of nanoparticles

9.  Nanoemulsion is a heterogeneous system and it
consist of two immisible phase, one phase is oil
phase ,other is aqueous phase, while the droplet
is of sub micron size range of 5-200nm.
 Nanoemulsions are submicron sized emulsion
that is under extensive investigation as drug
carriers for improving the delivery of
therapeutic agents
nanoemulsion

10.  Use in Cosmetic
 Use as anti-microbial agent
 Parenteral delivery
 Oral delivery
 Ocular & pulmonary delivery
 Nanoemulsion in cancer therapy
Applications of nanoemulsion

11.  It is a very small liposomes.
 It is a so small, in the Nanometer range
 Defination:-
Nanodevices existing symbiotically inside
biological cells, doing mechanosynthesis &
disassembly for it and replicating with the cell
similar to nanochondria.
NANOSOMES

12.  Phospholipids- lecithin, water soluble & oil soluble
ingredients
 Vitamin-C,vit-E ,sod.citrate, pot.malate.
Some examples of nanosomes.

13.  In cosmetics- In skin care ,hair care
 Targeting
 Diagnosis
 Therapy
APPLICATIONS OF NANOSOMES

14.  It is a tree like ,highly branched,
polymeric compounds.
 It is a polymer than branches “a tiny
molecular structure that interacts with
cells enabling scientists to probe,
diagnose, cure or manipulate them on a
nanoscale”.
dendrimers

15.  In delivery of drug
 Useful in therapetic agents in the prevention of
bacterial & viral infections.
 As coating agents
 Gene therapy
Applications of dendrimers

16.  Carbon nanotubes are allotropes of carbon
with a cylindrical nano stucture
 Nanotubes can be single walled carbon
nanotubes or multiwalled carbon nanotubes
in concentric fashion.
 These are tubular structure like a sheet of
graphite rolled in to a cylinder capped at one/
both ends by a bulky ball
NANOTUBES

17.  Gene therapy
 Cancer therapy
 Vaccine production
Applications of nanotubes

18.  These are very finely colloid, biphasic,
dispersed, solid drug particles in an
aqueous vehicle.
 Size below 1 meter
Nanosuspension

19.  Oral drug delivery
 Parental drug delivery
 Pulmonary drug delivery
 Ocular drug delivery
Applications of nanosuspension

20.  Pharmaceutical Applications of Nanoparticulate Drug-
delivery systems by “ Deepak Thassu” Page no.185-203
 Theory & practice in Novel drug delivery system by
“S.P Vyas”
A review article” Pharmacie Globle” International
journal of comprehensive pharmacy
www.google.com
REFERENCES

21. THANK YOU