The global market of bioprocessing companies is highly competitive today, and many manufacturing companies are thinking of revamping their manufacturing strategies. On the other hand, the industry has seen great emergence of novel manufacturing technologies, hence the adaption of such technologies is on the rise. The decision of whether to migrate from centralized manufacturing to decentralized manufacturing or not has become the vital part of strategy for industry driven manufacturing companies. We have compared these two manufacturing processes and for better understanding, we fetched out benefits of both.