This document discusses bacterial corneal ulcers. The cornea is prone to infection due to its exposure, but is normally protected by tears. A bacterial corneal ulcer can develop if the protective mechanisms are compromised, there is a predisposing eye condition, immunity is lowered, or the organism is very virulent. Clinical signs of a bacterial corneal ulcer include pain, watering, photophobia, blurred vision, redness, swollen lids, blepharospasm, conjunctival congestion, and a well-established ulcer with yellowish-white color, overhanging margins, necrotic floor, and surrounding edema.

1. BACTERIAL CORNEAL ULCER.
PATHOGENES
IS
PATHOLOGY.
CLINICAL
FEATURES.
BY:-
DR.AYESHA SARWAR.

2. BEING THE MOST ANTERIOR PART OF THE EYEBALL,
THE CORNEA IS EXPOSED TO ATMOSPHERE AND HENCE
PRONE TO GET INFECTED EASILY.
AT THE SAME TIME CORNEA IS PROTECTED FROM DAY-
TO-DAY MINOR INFECTIONS BY NORMAL DEFENCE
MECHANISMS PRESENT IN THE TEARS (Present in the
form of lysozyme and other proteins)
THERFORE, INFECTIVE BACTERIAL ULCER MAY
DEVELOP WHEN:-
Either the local defence mechanism is jeopardised.
Presence of local ocular predisposing disease.
Host’s immunity is compromised.
The causative organism is very virulent.

3. PATHOGENESIS.....

4. PATHOLOGY OF BACTERIAL
CORNEAL ULCER.....

5. Stages of corneal ulcer
(Pathology)
Regressive
 Progressive
Cicatrization
Leucocytic infiltration
PMN leucocytic infiltration
vascularisation

6. CLINICAL PICTURE (SIGNS AND SYMPTOMS)....
A 50year OLD MAN COMES WITH A HISTORY OF........
PAIN AND FOREIGN BODY SENSATION
WATERING FROM THE EYE
PHOTOPHOBIA
BLURRED VISION
REDNESS OF EYES.
SWOLLEN LIDS.
MARKED BLEPHAROSPASM.
CHEMOSED CONJUCTIVA.
A WELL ESTABLISHED CORNEAL ULCER (characteried by):-
Yellowish white area of ulcer...may be oval/irregular.
Margins of ulcer oval and overhanging.
Floor of the ulcer covered by necrotic material.
Stromal oedema present surrounding the ulcer area.