KBC Securities Entrepeneurial Summit 2015, presentatie van Prof. Dr. Ir. Esat-Stadius KU Leuven over succesvolle start-ups aan de KUL.

1. How to start-up @KU Leuven ?
Bart De Moor

2. – Academic education
– Scientific research
– Service to the community
= knowledge and technology transfer
• to society
• to industry

3. KU Leuven - 4000 researchers & 1500 faculty, 800 MEUR
Gasthuisberg – 1300 researchers, 800 MEUR
LERU (League of 22 European Research Intensive Universities) –
coordination centre
Thomson-Reuters ranking of most innovative universities:
- Ranked 16th worldwide
- Ranked 2nd Europe

4. Funding
Type of research (basic to applied)
Sizeofproject(smalltolarge)
FWO
FP7
IOF
Kennisplatformen
Hefboomprojecten
Mandaten
Innovation-project
EU
IDEAS
PEOPLE COOPERATION
SMEs
CIP
OT
IDO
GOA IWT – O&O
IWT - OZM
IWT - SBO
IWT – SBO
voortraject (m. f.)

6. Computational Biology
• Genomic data fusion
• NGS data analysis
• Graphical models & kernels
Applications
• Diagnosis of genetic disorders
• Disease gene discovery
• Disease management
Methodology
• Matrix/tensor algebra
• Classification and survival
• Multimodal Signal Processing
& Analysis
• Optimization in engineering
• Support vector machines
& kernel methods
• Advanced process control
• Datamining, information retrieval
& knowledge discovery
• Complex networks & nonlinear systems
• Numerical linear algebra
Bioinformatics/Computational Biology Biomedical Data Processing
Digital Signal Processing for Audio & Telecom
Audio Speech processing
• Speech Communications
• Public Address Systems
• Hearing Aids/Cochlear Implants
Digital Communications
• Wireline ADSL/VDSL
• Wireless
Systems, Models & Control

7. IWT Projects: SBO: 2;
Proeftuin:1
Fundamental Strategic Demand-driven
N.A. N.A.
N.A.N.A.
Projects: 13
Research
BELSPO IUAP: 2 ; VLIR: 2
Fellowships: PhD: 4; Postdoc: 6
IWT Fellowships phd: 10 IMEC: fellowships: 1
iMinds Medical IT 2014
SBO: 1
BOF
N.A.
FOD Kankerplan: 1
N.A.
FLANDERS
CARE
FL. Care Demo Project: 1
IWT Baekeland: 1
IWT innovation postdoc: 1
KU Leuven centra
IOF
Projects: 2: 2KP
Hercules collaborations: 3
KU Leuven
topfacilitiesGenomics Core
SyBioMA
LICT, LMTC
LBioSCENTer
IWT Projects: TBM: 4; O&O: 2;
Eurostars: 1
iMinds Medical IT ICON: 3;
Fallrisk , Nxt Sleep, b-SLIM
Projects: EU:5; ERC:3 ; MC ITN:3 ;
EFRO Interreg:1 ; COST: 2;
ERASMUS:1
DYSCO
Projects 8: GOA: 2; PF: 2;
BIL: 2; VES:1
Fellowships: DBOF PDM:2 CoE/PF
GOA
MaNet
http://www.esat.kuleuven.be/
bioinformatics/software.php
http://homes.esat.kuleuven.be/
~biomed/software.php
software
VLK: 1
VSC: TIER1:2
Industry: 1
BESTCOM

8. – Academic education
– Scientific research
– Service to the community
= knowledge and technology transfer
• to society
• to industry

9. Research
collaboration
(22)
• advice
• contract R&D
• projects with
government
support (IWT, EC,
etc.)
Intellectual
property rights
(10)
• intellectual
property rights
• licensing
Spin-off &
innovation
(10)
• spin-off creation
& growth
• networks &
regional dev.
• KU Leuven
Association
Finance, HR &
logistics
(39)
• financial
administration
• HRM
administration
Management (2)

10. IPTEC Award
2006 Stanford
2007 Tsinghua
2008 Leuven

11. Booming business
• 114 million euro income from research collaboration
• 1,774 new agreements (2014)
0
200
400
600
800
1000
1200
1400
1600
1800
2005 2006 2007 2008
2009
2010
2011
2012
2013
2014
463
598
812
981 1051
1263 1301
1724
1563
1774

12. Patents & Intellectual property
• 129 patent applications in 2014
– 586 active patent families
– 42 PCTs
• 87 million euro license-income
• Granted patent is often the basis for setting up a
spin-off company
In numbers 2014
Reported findings 177
Priority submissions 129
New patents 52

13. Examples of technology transfer

14. Basic
Research
Strategic
Valorisation
Patents
Licenses
BOF
IOF FP6/7
SME
Direct Contract
Research
KUL
Research
group
spinoff
NV
FFF BA/VC
founders employees
Fase 1
Creating a spin-off company
Fase 2

15. • Gemma Frisius Fund KU Leuven (GFF)
o Seed capital for spin-off companies
o GFF founded in 1997 & GFF II in 2002
• At the end of 2009 GFF and GFF II merged into one single fund
o Partners:
• KU Leuven (20% of capital)
• Two banks: KBC Private Equity (40%) and BNP Paribas Fortis Private
Equity (40%)
o Combination between:
• Knowledge and technology transfer expertise
(university)
• Financial expertise (financial partners)
o Not restricted to one technology domain
o 27 million euro invested in 42 spin-off
companies
Seed money

16. Leverage

17. 0
20
40
60
80
100
120
1981 1983 1985 1987 1989 1991 1993 1995 1997 1999 2001 2003 2005 2007 2009 2011 2013
Cumulative number of spin-offs created
Total no. of active spin-offs
Total no. of spin-offs
• 105 spin-off companies started, 87 still active; together
+/- 4,100 employees (numbers 2014)
• 760 million euro external capital (2005-2014 only)
• 7 successful flotations (IPOs)
Impact of spin-offs

18. • Engineering
• Micro-electronics & ICT
Our jewels

19. • Consultancy
• Biomedical
Our jewels (c’ted)

21. Yesterday’s closing dinner Cartagenia:
Founders & investors

22. Student entrepreneurs
Leuven
Community
for innovation
Driven
Entrepreneurship

23. LRD
GFF
Leuven.Inc
Science
Parks
KU Leuven
Industry
RegionFinancial
world
The Leuven biotope

24. • Critical mass of high quality research & projects
• Multidisciplinary team & high value support
• Favourable entrepreneurial climate within the university
• Clear incentives to encourage researchers
• Instruments and networks that support technology
transfer & entrepreneurship
• Legal context in Flanders
• The Leuven eco-system & biotope: Leuven MINDGATE
Succes factors

25. Leuven MINDGATE