What is Thalassemia and Types of Thalassemia? Thalassemia is an inherited blood disorder characterised by low haemoglobin (Haemoglobin is an iron rich protein present within the Red Blood Cells of the body. Haemoglobin is responsible for carrying oxygen to all parts of the body). http://www.bmthospitalindia.com/Pediatric-Thalassemia.html

1. What is Thalassemia
Thalassemia is an inherited blood disorder characterised by
low haemoglobin (Haemoglobin is an iron rich protein
present within the Red Blood Cells of the body.

2. Types of Thalassemia
 Thalassemia Major
 Thalassemia Minor or Thalassemia Trait.
 Thalassemia Intermedia

3. What are the Symptoms of
Thalassemia Major?
The symptoms appear between 3-7 years age. The
child starts becoming listless, irritable and pale. The
parents often visit the doctor several times before
this is detected.

4. What are the Symptoms of
Thalassemia Intermedia?
This depends on the severity of the affection of
globin gene production. In more severe form, the
age of onset and symptoms are similar to
Thalassemia Major.

5. What are the Symptoms of
Thalassemia Trait?
This does not produce any symptom and is often
detected on routine blood tests. The red cell
morphology bears all the features of iron
deficiency, although serum iron levels are high in
these patients.

6. How do we Diagnose Thalassemia?
 Complete Blood Count
 Hemoglobin Electrophoresis
 Genetic Tests
Detail : http://www.bmthospitalindia.com/Pediatric-Thalassemia.html

7. How do we treat Thalassemia
Major?
 There are two approaches to the treatment of
Thalassemia major
› Transfusion and Chelation (Removal of iron from body)
› Bone Marrow Transplantation (BMT)

8. What is the best age for patients
with Thalassemia to undergo
Bone Marrow Transplantation?
 Best age is between 2 to 5 years.
 However, successful BMT has been carried out in
older children and young adults.

9. Who can be the donor?
 Matched Family donor is the best option.
 A person who has Thalassemia trait can be a donor
for a patient with Thalassemia major.
 Results with Matched Unrelated Donor are
improving.
 Recent studies have shown that HAPLOIDENTICAL
(Half Matched) FAMILY DONOR might be a viable
option for these patients.

10. Contact Us
Website : http://www.bmthospitalindia.com/Pediatric-
Thalassemia.html
Phone : +91-8130000120, 011-43066353
Email : info@bmthospitalindia.com

11. Thank You