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Principles of Surgical Oncology
Chea Chan Hooi
Surgeon
Sibu Hospital
Content
• Definition
• Introduction
• Epidemiology
• Multidisciplinary effort
• Classification
– Role
– Intent
– Timing
• Q&A
Definition
• The application of surgery in the management
of cancer patients
Introduction
• Increasing incidence of cancer worldwide
• Better patient outcomes in highly-specialised
cancer centers
• Various treatment modalities nowadays
• Various surgical techniques
• Multidisciplinary, multifactorial management
Multidisciplinary effort
Roles
• Diagnostic
• Staging
• Prognosticate
• Curative
• Restorative
• Palliative
• Prophylactic
Diagnostic
• Biopsy
– FNAC
– Core needle
– Surgery
• Excision
• Incision
• Mode of surgery
– Open
– Laparoscopic
Staging
• Determine the extent of tumour invasion, either
local or distant
• Broadly classified into early, locally-advanced and
metastatic
• Assists in determining optimal managing
strategies
• Directly correlates with prognosis
• Examples
– TNM staging system
– Duke staging sytem
• Examples of surgical staging
– Staging laparoscopy for locally advanced GI
malignancy
– Axillary surgery for breast carcinoma
• Sentinel lymph node biopsy
• Axillary sampling Level 1
• Axillary dissection Level 2
• Axillary clearance Level 3
Prognosticate
• Correlates with staging
Curative
• Total excision of all tumour cells (in reality almost
impossible)
• Adequacy of resection
– Margin
• R0 Microscopically negative
• R1 Microscopically involved
• R2 Grossly involved
– LN
• Preserve restorative options as much as possible
Palliative
• To overcome some symptom-producing
consequence of the tumour in a patient
deemed incurable
• Limited to patients whom are relatively fit
with expected survival > 6 weeks
• Either resect or by-pass
Restorative
• To return the organ or system to its
original/anatomic/functional state as much as
possible
• Example
– Reconstruction post maxillofacial tumour resections
– Various methods of reconstruction post gastrectomy
– Closure of covering ileostomy post ULAR
– Breast reconstruction post mastectomy
Intent
• Curative
– To achieve clearance of all cancer cells, hence cure
• Palliative
– To reduce, control or minimise cancer cells with
the aim to reduce rate of cancer growth, thus
prolonging meaningful patient survival
Timing
• Neoadjuvant
– Surgical resection after other treatment modality had
been initiated
– Reduce the bulk of large tumour (down-staging)
• To improve likelihood of successful resection (R0)
• To allow less destructive surgeries
– AKA “sandwich therapy” in UGI carcinoma
management
• Adjuvant
– Surgical resection prior to other treatment modalities
TQ!
Q&A?

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Principles of surgical oncology

  • 1. Principles of Surgical Oncology Chea Chan Hooi Surgeon Sibu Hospital
  • 2. Content • Definition • Introduction • Epidemiology • Multidisciplinary effort • Classification – Role – Intent – Timing • Q&A
  • 3. Definition • The application of surgery in the management of cancer patients
  • 4. Introduction • Increasing incidence of cancer worldwide • Better patient outcomes in highly-specialised cancer centers • Various treatment modalities nowadays • Various surgical techniques • Multidisciplinary, multifactorial management
  • 5.
  • 6.
  • 7.
  • 9. Roles • Diagnostic • Staging • Prognosticate • Curative • Restorative • Palliative • Prophylactic
  • 10. Diagnostic • Biopsy – FNAC – Core needle – Surgery • Excision • Incision • Mode of surgery – Open – Laparoscopic
  • 11.
  • 12.
  • 13. Staging • Determine the extent of tumour invasion, either local or distant • Broadly classified into early, locally-advanced and metastatic • Assists in determining optimal managing strategies • Directly correlates with prognosis • Examples – TNM staging system – Duke staging sytem
  • 14. • Examples of surgical staging – Staging laparoscopy for locally advanced GI malignancy – Axillary surgery for breast carcinoma • Sentinel lymph node biopsy • Axillary sampling Level 1 • Axillary dissection Level 2 • Axillary clearance Level 3
  • 15.
  • 16.
  • 17.
  • 18.
  • 20. Curative • Total excision of all tumour cells (in reality almost impossible) • Adequacy of resection – Margin • R0 Microscopically negative • R1 Microscopically involved • R2 Grossly involved – LN • Preserve restorative options as much as possible
  • 21. Palliative • To overcome some symptom-producing consequence of the tumour in a patient deemed incurable • Limited to patients whom are relatively fit with expected survival > 6 weeks • Either resect or by-pass
  • 22. Restorative • To return the organ or system to its original/anatomic/functional state as much as possible • Example – Reconstruction post maxillofacial tumour resections – Various methods of reconstruction post gastrectomy – Closure of covering ileostomy post ULAR – Breast reconstruction post mastectomy
  • 23. Intent • Curative – To achieve clearance of all cancer cells, hence cure • Palliative – To reduce, control or minimise cancer cells with the aim to reduce rate of cancer growth, thus prolonging meaningful patient survival
  • 24. Timing • Neoadjuvant – Surgical resection after other treatment modality had been initiated – Reduce the bulk of large tumour (down-staging) • To improve likelihood of successful resection (R0) • To allow less destructive surgeries – AKA “sandwich therapy” in UGI carcinoma management • Adjuvant – Surgical resection prior to other treatment modalities