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Global Agtech Investors Network
      Cultivating Innovation
Cultivating innovation
                   •  Strategic partnerships and affiliations
                      –  BRDG Park, Danforth Plant Science Center,
                         Canadian Consulate, iBIO, MHIN, Missouri
                         Technology Corporation NVCA, RCGA, St.
                         Louis Economic Council,
                   •  Meetings and networking forums
GAIN cultivates    •  Member-exclusive resources:
innovation and         –  GAIN Innovation Cache™
Promotes capital
                       –  Ag Explorer™
formation for
Agtech             •  Other public resources
                       –  GAIN 50 Stock Market Index
                       –  GAIN Insight™
Mega-Trends in Agriculture

                  • Increasing demand                                         • Increasing demand
                   for food                                                    for biofuels and
                  • Decreasing amount                                          renewable energy
                   of land per capita



                                                             Increasing
                                          Growing           need for alt.
                                           world               energy
Future                                   population         feedstock's
investments in
agriculture
will largely be                            Growing
                                            wealth
                                                               Weather
                                                              variability
driven by four
trends            • Increasing meat
                   consumption, need
                   for feed
                                                                              •  Yield losses due to
                                                                               adverse weather
                                                                              • Requirement to
                  • Decreasing stocks                                          reduce greenhouse
                                                                               gases




                                        Meta analysis, Crop America, Elanco, WJS, other readings
Global Challenges – Population Growth


           By 2050, population will grow by 37%, reaching more than 9 billion
Billions                        or … three more Chinas




                                               More Developed Regions




                                                                                       .
   United Nations, World Population Prospects: The 2004 Revision (medium scenario), 2005
Global Income Growth Per Capita

                                                                                                                          2000-­‐2030F	
  Growth	
  Shares	
  
                                                                                                                                       Africa	
   India	
  
                                                                                                                                        2%	
   3%	
  
                                                                                                               South	
  America	
                                                    Middle	
  East	
  
                                                                                                                    7%	
                                      Eastern	
  
                                                                                                                                                                                        9%	
  
                                                                                                                                                              Europe/
                                                                                                                                                               Russia	
  
                                                                                                                                                                11%	
  
                                                     12	
  
Thousand	
  real	
  2005	
  US$	
  Per	
  Year	
  




                                                                                                                                China	
  
                                                                                                                                 14%	
  
                                                     10	
  
                                                                                                5.00	
                                                                            EU-­‐27	
  
                                                       8	
                                                                                                                         23%	
  
                                                                                                                                      North	
  America	
  
                                                       6	
                   -­‐0.05	
                                                     27%	
  

                                                       4	
  
                                                               6.37	
                                                                                                       Other	
  Asia	
  
                                                       2	
                                                                                                                     4%	
  

                                                       0	
  
                                                               1970	
     1970-­‐2000	
     2000-­‐2030F	
  


                                                                                                                             Source: IHS Global Insights, Agriculture Division
Revenue Growth
                                 Sub Segments




CAGR of 37% 2003-08
Expected to continue at 21%
2009-13 (to revenue of $90B)




                                                Capgemini
The Demand - Supply Gap
                  Area of land under cultivation



M’s hectares




                                             USDA



                          Year
The Demand - Supply Gap
    Cultivated land per capita




                                 USDA
The Demand - Supply Gap

70% of this food must
come from efficiency -
Improving technology
                         Food
                         Demand
                         2050
               2X


  Food                     Biomass
  Demand
  Today
                  Plus


                                  U.N. FAO
Population and Income
                               Drive Food Demand
                  180
                  160
                  140
                  120
                  100                                                                   Grain
                                                                                        Vegetables
                    80
                                                                                        Meat
                    60
                                                                                        Milk
                    40
                    20
                       0
                             1975 1980 1985 1990 1995

Taiwan Council of Agriculture, China Statistical Yearbook and Nomura Global Economics
•  New Challenges
                                   –  Variable stringency of legislation
                                      in various countries
                                   –  Changing and possibly divergent
                                      perception of GMO’s and
                                      agrichemicals
Challenges                         –  The need for product
In addition to the traditional        differentiation between
challenges in agriculture such        expanding markets
as weather and prevailing
economic conditions,
                                   –  Shifts from product to service
agriculture in the future will        based offerings
face new and increasingly
complex hurdles.
•  Success will require….
                                   –  Capacity to be flexible
                                      •  Adjust from measurable plans
                                   –  Planning methods that allow for
                                      multiple outcomes
                                   –  Working with all stakeholders
Meeting Challenges                    including political decision
Companies must be able to             makers, retailers, consumers and
adapt to their increasingly           importantly growers
complex environment and
capitalize in established and      –  And……
emerging markets.
                                          INNOVATION!!!!!!
Venture Capital Investment in Agriculture




Innovation
The need for innovation in
agriculture requires capital
which can come from
corporations, venture capital
and of increasing importance
angel investors



                                                        PWC Moneytree, NVCA
Animal Health as a Component
                                     of Agriculture
                             •  Animal health is of growing importance to the
                                world
                                   –  Meat and dairy production to double by 2050
                                        •  Meat consumption in China doubled from
                                           1985 (44lb/person) to 2000 (90lb) and is
                                           expected to dbl again by 2030
                                   –  Concern over Zoonotic diseases!
                                        •  Not well publicized, but a huge threat
                                        •  80% of animal pathogens are multihost*
                                        •  Ex. The next smallpox (cowpox)
                                   –  Food safety, “farm to fork” tracking, new
                                      handling and packaging,
                             •    NVCA – industry tracking spotty at best, fragmented
*Michigan State University
                                  investor segmentation, reporting incomplete or
                                  inaccurate
Animal Health as a Component
                                 of Agriculture
                         •  $13B spent on animal health products
                             –  40% companion, 60% production
                         •  Animal health product FDA submissions and
                            approvals are down.
                             –  2007 – 12 of 18 submissions were approved
                             –  2010 – only 2 of 6 approved
                         •  R&D lacking, large companies cutting back,
                            looking to start-ups for innovation
                         •  Structural changes in industry include
                            emergence of generics, changes in distribution,
                            the internet
Brakke Consulting, FDA
•  Examples of innovations
                                  impact on food production and
                                  agriculture
                                  –  Milk production now requires
                                     65% less water and 90% land
                                     than in 1944
Innovations Importance to
Animal Health/Production          –  76% less manure is being
Innovation has been                  produced/gallon of milk
important to the production       –  Genetic selection and
of meat and dairy for
centuries, however, over the         improvements in nutrition has
last 70 years huge advances          increased the slaughter weight of
have been made and need to           chickens 4-6x since ‘57
continue.


                                                         Elanco report
•  Companion animal industry is changing
                                    rapidly
                                    –  Vet practices trends 2001 -2009
                                        •  # of clients/vet down 17% (1299 –
                                           1070)
                                        •  # of patients seen/week decreased 12%
                                           (75 – 66)
                                        •  Decreases cause vets to increase fees to
Market Change                              cover fixed costs

There is a lot of change going
                                    –  30% of pet owners use internet to self
on in both companion and               diagnose pets symptoms
feed stock animal health.                •  Vets are seeing much sicker animals
These changes should                     •  Owners get “sticker shock” at the cost
represent opportunity for                   of care
innovators and investors            –  Internet medical supply/pharmaceutical
                                       providers impacting business
•  Food animal market changes
                                 –  Food shortages (high prices) and dry
                                    conditions are causing cattle and calves
                                    to be slaughtered at record numbers
                                     •  Short term supply issues, husbandry
                                        opportunities
                                     •  Meat prices projected to remain high
                                     •  Stress on herds increases disease and
Food Animal Changes                     infection

Increasing demand for meat    •  Pressure to reduce use of antibiotics
and dairy products is place      in feed and other ”un-natural”
new stresses on the market
which causes changes to          additives creates animal growth,
occur. Weather variability       food safety and market issues
also forces change
•  New animal uses for “old” human
                                  therapies
                                  –  Human pharma seems to be largely
                                     ignoring this opportunity
                               •  Conversion of well known and
                                  effective drugs to OTC
                               •  Technologies to help Vets analyze
                                  practice trends to maximize revenue
Companion Animal                  opportunities
Opportunities                     –  Most Vets do not analyze practice
Despite changes in the               trends and missed revenue
provision of care for                opportunities!
companion animals, many
opportunities for innovation   •  Nutritional products with another
and new products abound           function, such as….
                                  –  Joint, cardiovascular, ophthalmic and
                                     coat quality health
•  Genetically engineered meat
                                   animals
                                   –  Higher protein, vitamin content,
                                      other healthy components
                                •  Cloned animals
Food Animal                        –  FDA guidelines 2010
Opportunities
                                •  New packaging, convenience,
Increased demand for meat
and dairy are presenting both
                                   keep fresh
challenges and opportunities    •  Food safety
for growers, innovators and
investors                          –  Tracking, POP diagnostics
•  Agriculture is not an
                                  optional industry!!!
                                    –  Every person on earth must
                                       eat and drink, hopefully,
                                       clean water
                               •    Favorable demographics
Reasons to be bullish          •    Increasing wealth
There are many reasons to
be excited about the future    •    Innovation is required!
for investing in agriculture
                               •    Food prices increasing,
                                    more income to spend on
                                    innovation
Join GAIN
•  Become a member of the Global
   Agtech Investors Network.
•  Visit aginvestors.com/join-us.
OR
•  Contact Dan Broderick, president
   and founder, at
   dan@aginvestors.com.
Thank you
   Dan Broderick
dan@aginvestors.com

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Mega-Trends in Agriculture

  • 1. Global Agtech Investors Network Cultivating Innovation
  • 2. Cultivating innovation •  Strategic partnerships and affiliations –  BRDG Park, Danforth Plant Science Center, Canadian Consulate, iBIO, MHIN, Missouri Technology Corporation NVCA, RCGA, St. Louis Economic Council, •  Meetings and networking forums GAIN cultivates •  Member-exclusive resources: innovation and –  GAIN Innovation Cache™ Promotes capital –  Ag Explorer™ formation for Agtech •  Other public resources –  GAIN 50 Stock Market Index –  GAIN Insight™
  • 3. Mega-Trends in Agriculture • Increasing demand • Increasing demand for food for biofuels and • Decreasing amount renewable energy of land per capita Increasing Growing need for alt. world energy Future population feedstock's investments in agriculture will largely be Growing wealth Weather variability driven by four trends • Increasing meat consumption, need for feed •  Yield losses due to adverse weather • Requirement to • Decreasing stocks reduce greenhouse gases Meta analysis, Crop America, Elanco, WJS, other readings
  • 4. Global Challenges – Population Growth By 2050, population will grow by 37%, reaching more than 9 billion Billions or … three more Chinas More Developed Regions . United Nations, World Population Prospects: The 2004 Revision (medium scenario), 2005
  • 5. Global Income Growth Per Capita 2000-­‐2030F  Growth  Shares   Africa   India   2%   3%   South  America   Middle  East   7%   Eastern   9%   Europe/ Russia   11%   12   Thousand  real  2005  US$  Per  Year   China   14%   10   5.00   EU-­‐27   8   23%   North  America   6   -­‐0.05   27%   4   6.37   Other  Asia   2   4%   0   1970   1970-­‐2000   2000-­‐2030F   Source: IHS Global Insights, Agriculture Division
  • 6. Revenue Growth Sub Segments CAGR of 37% 2003-08 Expected to continue at 21% 2009-13 (to revenue of $90B) Capgemini
  • 7. The Demand - Supply Gap Area of land under cultivation M’s hectares USDA Year
  • 8. The Demand - Supply Gap Cultivated land per capita USDA
  • 9. The Demand - Supply Gap 70% of this food must come from efficiency - Improving technology Food Demand 2050 2X Food Biomass Demand Today Plus U.N. FAO
  • 10. Population and Income Drive Food Demand 180 160 140 120 100 Grain Vegetables 80 Meat 60 Milk 40 20 0 1975 1980 1985 1990 1995 Taiwan Council of Agriculture, China Statistical Yearbook and Nomura Global Economics
  • 11. •  New Challenges –  Variable stringency of legislation in various countries –  Changing and possibly divergent perception of GMO’s and agrichemicals Challenges –  The need for product In addition to the traditional differentiation between challenges in agriculture such expanding markets as weather and prevailing economic conditions, –  Shifts from product to service agriculture in the future will based offerings face new and increasingly complex hurdles.
  • 12. •  Success will require…. –  Capacity to be flexible •  Adjust from measurable plans –  Planning methods that allow for multiple outcomes –  Working with all stakeholders Meeting Challenges including political decision Companies must be able to makers, retailers, consumers and adapt to their increasingly importantly growers complex environment and capitalize in established and –  And…… emerging markets. INNOVATION!!!!!!
  • 13. Venture Capital Investment in Agriculture Innovation The need for innovation in agriculture requires capital which can come from corporations, venture capital and of increasing importance angel investors PWC Moneytree, NVCA
  • 14. Animal Health as a Component of Agriculture •  Animal health is of growing importance to the world –  Meat and dairy production to double by 2050 •  Meat consumption in China doubled from 1985 (44lb/person) to 2000 (90lb) and is expected to dbl again by 2030 –  Concern over Zoonotic diseases! •  Not well publicized, but a huge threat •  80% of animal pathogens are multihost* •  Ex. The next smallpox (cowpox) –  Food safety, “farm to fork” tracking, new handling and packaging, •  NVCA – industry tracking spotty at best, fragmented *Michigan State University investor segmentation, reporting incomplete or inaccurate
  • 15. Animal Health as a Component of Agriculture •  $13B spent on animal health products –  40% companion, 60% production •  Animal health product FDA submissions and approvals are down. –  2007 – 12 of 18 submissions were approved –  2010 – only 2 of 6 approved •  R&D lacking, large companies cutting back, looking to start-ups for innovation •  Structural changes in industry include emergence of generics, changes in distribution, the internet Brakke Consulting, FDA
  • 16. •  Examples of innovations impact on food production and agriculture –  Milk production now requires 65% less water and 90% land than in 1944 Innovations Importance to Animal Health/Production –  76% less manure is being Innovation has been produced/gallon of milk important to the production –  Genetic selection and of meat and dairy for centuries, however, over the improvements in nutrition has last 70 years huge advances increased the slaughter weight of have been made and need to chickens 4-6x since ‘57 continue. Elanco report
  • 17. •  Companion animal industry is changing rapidly –  Vet practices trends 2001 -2009 •  # of clients/vet down 17% (1299 – 1070) •  # of patients seen/week decreased 12% (75 – 66) •  Decreases cause vets to increase fees to Market Change cover fixed costs There is a lot of change going –  30% of pet owners use internet to self on in both companion and diagnose pets symptoms feed stock animal health. •  Vets are seeing much sicker animals These changes should •  Owners get “sticker shock” at the cost represent opportunity for of care innovators and investors –  Internet medical supply/pharmaceutical providers impacting business
  • 18. •  Food animal market changes –  Food shortages (high prices) and dry conditions are causing cattle and calves to be slaughtered at record numbers •  Short term supply issues, husbandry opportunities •  Meat prices projected to remain high •  Stress on herds increases disease and Food Animal Changes infection Increasing demand for meat •  Pressure to reduce use of antibiotics and dairy products is place in feed and other ”un-natural” new stresses on the market which causes changes to additives creates animal growth, occur. Weather variability food safety and market issues also forces change
  • 19. •  New animal uses for “old” human therapies –  Human pharma seems to be largely ignoring this opportunity •  Conversion of well known and effective drugs to OTC •  Technologies to help Vets analyze practice trends to maximize revenue Companion Animal opportunities Opportunities –  Most Vets do not analyze practice Despite changes in the trends and missed revenue provision of care for opportunities! companion animals, many opportunities for innovation •  Nutritional products with another and new products abound function, such as…. –  Joint, cardiovascular, ophthalmic and coat quality health
  • 20. •  Genetically engineered meat animals –  Higher protein, vitamin content, other healthy components •  Cloned animals Food Animal –  FDA guidelines 2010 Opportunities •  New packaging, convenience, Increased demand for meat and dairy are presenting both keep fresh challenges and opportunities •  Food safety for growers, innovators and investors –  Tracking, POP diagnostics
  • 21. •  Agriculture is not an optional industry!!! –  Every person on earth must eat and drink, hopefully, clean water •  Favorable demographics Reasons to be bullish •  Increasing wealth There are many reasons to be excited about the future •  Innovation is required! for investing in agriculture •  Food prices increasing, more income to spend on innovation
  • 22. Join GAIN •  Become a member of the Global Agtech Investors Network. •  Visit aginvestors.com/join-us. OR •  Contact Dan Broderick, president and founder, at dan@aginvestors.com.
  • 23. Thank you Dan Broderick dan@aginvestors.com