31. The inner is microporous membrane, which is made up of cellulosic material containing some pore forming agents, covered by a semipermeable membrane.
65. Drugs administered orally would encounter a spectrum of pH ranging from 7 in the mouth, 1 - 4 in the stomach and 5 - 7 in the intestine.
66.
67.
68.
69. This leaves a microporous membrane of intestinal fluid insoluble polymer of Ethylcellulose, which controls the release of drug from the core tablet.
73. Principle A Cation exchange resin generally has Sulphonic and Carboxylic functional groups as an integral part of the resin and an equivalent amount of cationic drug molecules. An Anion exchange resin generally has quaternary ammonium groups and polyalkylamine functional groups as an integral part of the resin and an equivalent amount of anionic drug molecules.
83. General preparation of drug resinates Column process: A highly concentrated drug solution is eluted through a bed or column of the resin until equilibrium is established. Batch process: The resin particles are stirred with a large volume of concentrated drug solution.
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