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CONSANGUINEOUS ATOPY, GENETIC NURSING, BY MR. DINABANDHU BARAD

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Consanguinous marriage

  1. 1. CONSANGUINEOUS ATOPY BY: Mr. Dinabandhu Barad MSc Tutor, SNC,SOA,DTU
  2. 2. DEFINITION In clinical genetics, a consanguineous marriage is defined as a union between two individuals who are related as second cousins or closer.
  3. 3. DEGREE OF COUSINHOOD
  4. 4. DEGREE OF COUSINHOOD
  5. 5. DEGREE OF COUSINHOOD
  6. 6. DEGREE OF COUSINHOOD
  7. 7. REASONS FOR CHOOSING TO MARRY A COUSIN • Consanguinity is a deeply rooted cultural trend in certain communities. • More favourable for the women`s status. The wife would have better relationship with her in-laws and could be protected by them in time of need. • There is a general belief that marrying within the family reduces the possibilities of hidden health and financial uncertainties.
  8. 8. REASONS FOR CHOOSING TO MARRY A COUSIN • Premarital negotiations regarding financial matters of marriage are more easily conducted, keeping the money and property within the family. • Strengthens family ties, and enforces family solidarity.
  9. 9. FACTORS AFFECTING CONSANGUINITY RATES • Consanguinity rates are higher in rural than urban settings of a certain community. • Higher female education reduces the rate of first cousin marriages. • First cousin marriages are more common when the parents of the couple are consanguineous.
  10. 10. FACTORS AFFECTING CONSANGUINITY RATES • In the same community, consanguinity rates are higher among Muslims than among Christians, for example in Lebanon, Jordan, South India.
  11. 11. FACTORS MAY DECREASE CONSANGUINITY RATE • Higher female education • Higher age at marriage • Low fertility • More mobility from rural to urban • Better economic status of families
  12. 12. EFFECT OF CONSANGUINITY • Stillbirth rates are either similar or slightly higher among consanguineous couples than the non-related couples. • There is a positive association between parental consanguinity and increased infant and childhood mortality. • Many studies have shown a positive association between parental consanguinity and congenital heart defects. • The association of consanguinity with cleft lip and palate, and neural tube defects is not clear.
  13. 13. EFFECT OF CONSANGUINITY • Among genetic disorders, only autosomal recessive disorders are strongly associated with consanguinity. • The association of NCD’s ( such as diabetes, hypertension) with parental consanguinity is still not clear.
  14. 14. COUNSELLING • Genetic counselling is the process by which clients or their relatives, at risk of an inherited disorder, are advised to prevent, avoid or ameliorate the disorder. • They are advised on • the consequences and nature of the disorder, • the probabilities of developing or transmitting it, • the choices open to them in management and planning of their families.
  15. 15. COUNSELLING Genetic counsellors provide useful information and support to families who may be at risk of inherited disorders. • They are involved • in identification of families at risk • investigation of problems presented by the family • interpretation of information about the disorder • analysis of inheritance patterns and • evaluation of risks of recurrence • reviewing testing options available to the family.

CONSANGUINEOUS ATOPY, GENETIC NURSING, BY MR. DINABANDHU BARAD

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