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CHOICE OF GUIDING CATHETERS:
TRANS-FEMORAL AND
TRANS-RADIAL APPROACH
Satyam Rajvanshi
• Guide catheters are essential tools for Pecutaneous
Coronary Intervention
• Understanding construction, design & performance
characteristics facilitate their appropriate selection
• Selection of Guide catheters seems elementary but
makes the difference between a successful and failed
PCI procedure
Functions of a Guide
• Vehicle for contrast injection
• Measurement of Pressure
• Conduit for wire and device transport
• Support for device advancement
Guiding vs. Diagnostic catheters
A Guide has
– Stiffer shaft
– Re-enforced construction (3 vs. 2 layers)
– Larger internal diameter (ID)
– Shorter & more angulated, non tapering atraumatic tip
Guide: 3 basic components
Hub or ‘Handle’
Shaft – Braided polyurethane or polyethylene. Softens from
proximal to distal tip
Tip – Soft and atraumatic, varying shapes and sizes
Length – usually 100 cms
Many catheters have tertiary curve
Cross section of catheter
Strength
Support
Flexibility
Curve retention
Kink resistance
Polyurethanene or
Polyethylene
1:1 Torque transmission
Kink resistance
Radiopacity
Stainless steel/ Kevlar
Large lumen for Device
compatibility
Lubricious material for smooth
device delivery
Atraumatic and radiopaque tip
PTFE (Teflon)/Silicone
DECISIONS IN GUIDE SELECTION
Upto 250 shapes available!
Factors to consider
Goal Factors to consider
Co-axial
alignment
• Coronary or graft anatomy – ostium location; vessel orientation
• Access site – Femoral/Radial, Left/Right
• Aortic arch configuration, Aortic root size
• Body habitus
Support • Lesion – Simple / Complex (Long/calcified/Tortuous/Bifurcation/CTO)
• Device – type, size, trackeability
3 basic attributes
Size
Shape
Support
Larger Guiding
Higher bleeding risk
but
Greater coronary opacification
Better torque transmission
More passive support
More complex PCI possible
Smaller Guiding
Lower bleeding risk
but
Less coronary opacification
Poorer torque transmission
Less passive support
Less complex PCI possible
Guide size and PCI device
Guide size PCI device (s)
5 Fr
(1.42-1.50 mm I.D.)
POBA
Drug coated balloon
Scoreflex balloon
Most coronary stents
Rotablator burr size 1.25 mm
Some IVUS catheters
Kissing with small profile balloons and
.010” wire
6 Fr
(1.73-1.80 mm I.D.)
Standard angioplasty and stenting
Some bifurcation PCI, Kissing with
small profile balloons
Flextome Cutting balloon
6 Fr Thrombuster/Export catheter
Rotablator burr size 1.5 mm
IVUS catheters
7 Fr
(1.98-2.06 mm I.D.)
Simultaneous 2 rapid exchange
balloons
Simultaneous 2 stent deployment
Simultaneous 2 microcatheters
7 Fr Thrombuster
Rotablator burr size 1.75 and 2 mm
8 Fr
(2.24-2.30 mm I.D.)
Simultaneous 2 OTW balloons
Rotablator burr size 2.25 mm
Factors determining Support
• Catheter size – Larger catheter, more support
• Co-axial alignment
• Catheter support point
– Maximum support when angle between point of
immediate support and proximal coronary artery is 0
degree – directly opposite the ostia
– Larger contact area at support point – more support
• Deep Intubation into vessel (‘Active support’)
• Physical characteristics of catheter
Passive Support
• Relies on properties of the
shaft and tip to maintain
position in the ostium
• Support provided by either
vascular anatomy or
catheter composition/curve
shape
• Minimal manipulation of
the guide is required
Active Support
• Uses aortic root to form
desired curve shape and
provide backup support
• Relies on active
manipulation of guiding
catheter to
– Obtain stable position
– Seat coaxially
– Deep seating into the
vessel: ostia should be
disease-free
– Pre-select LAD or LCX
Aortic Width
Aortic Width: determines curve length
Coronary Anatomy Ostial Origins
• Left Main – usually antero-inferior and leftward from LCS
• LAD - usually anterio-superior from the left main
• LCX – usually postero-inferior from the left main
• RCA – usually anterior from RCS
• SVGs – usually anterior
Coronary Anatomy Ostial Variations
• Coronary ostial location:
– High
– Low
– Anterior
– Posterior
• Coronary ostial orientation:
– Horizontal
– Inferior
– Superior
Coronary Anatomy Ostial Variations
• Coronary ostial location:
– High
– Low
– Anterior
– Posterior
• Coronary ostial orientation:
– Horizontal
– Inferior
– Superior
– Shepherd’s crook (RCA only)
GUIDE CATHETERS FOR
TRANSFEMORAL INTERVENTION
• Most common catheters
– Judkins
– Amplatz
– Extra Backup support – EBU (Medtronic)
XB (Cordis)
Voda, Qcurve (Boston)
• Catheters with niche use
– Multipurpose – RCA graft, High LM takeoff
– IMA cath – LIMA, Superior takeoff RCA or RCA graft
– LCB, RCB cath – SVG
Judkins catheters
• JL – primary (35°) Secondary
(180°) and tertiary (35°)
curve fitting aortic root
anatomy – engages LMCA
ostium without much
manipulation
• JR – requires clockwise
rotation to engage RCA
35°
180°
35°
Judkins catheters
• Aortic width and ostial
anatomy determines the
curve length
JL JR
Normal habitus
and aortic root size
4.0 4.0
Small habitus and
aortic root size
3.5, 3.0 4.0, 3.5
Large habitus and
dilated aortic root
5.0, 6.0 4.0, 4.5,
5.0
Superior takeoff
RCA
3.0, 3.5
Separate ostia –
LAD, LCX
Smaller
JL for
LAD,
Larger
for LCX
Judkins catheters
• Short LM
selective hooking of
LAD/LCX
• Toward the LAD -
Counter-clockwise rotation
• Toward the LCX -
Clockwise rotation
Limitations of Judkins Guide
• As 1° curve is fixed - may not be co-axial with
the artery
• May be difficult to pass balloons - as catheter
makes an angle of 90° with ostium
• JL - point of contact on ascending aorta - very
high & narrow- ↑ chance of prolapse &
dislodgement
• JR - no point of contact on Asc Aorta -
extremely poor support
The Amplatz Guide
• Secondary curve rest against the
noncoronary posterior aortic cusp
• Offers firm platform for
advancement of device
• Best in the case of a short LM, with
downgoing left circumflex artery
(LCX)
• Tip points slightly downward -
higher danger of ostial injury
causing dissection
Amplatz Guide
• Selection of the proper size for
an Amplatz guide is essential
– Size 1 is for the smallest
aortic root
– size 2 for normal
– size 3 for large roots
• Attempts to force engagement
of a preformed Amplatz guide
that does not conform to a
particular aortic root increase
risk of complication
• If tip does not reach the ostium and keep lying below it -
guide is too small
• If tip lies above the ostium - guide is too large
• When RCA ostium is very high - left Amplatz guide may be
used to engage the right ostium
Withdrawal of an Amplatz Guide
• Must be carefully disengaged from the coronary artery
• A simple withdrawal from the vessel can cause the tip to
advance farther into the vessel and cause dissection
• To disengage - first advance guide slightly to prolapse the tip
out of the ostium
• Then rotate the guide so that tip is totally out of the ostium
before withdrawing it
Long tip catheters (Extra Support)
• Voda, XB, EBU
• Advantages
– coaxial intubation
– better support & stability due
to large area of contact
between catheter &
contralateral aortic wall
– precise control and
manipulation
– lack of bends - improve
advancement of devices,
decrease the loss of supportive
forces
– safety
Voda EBU
Extra-Back-Up Guide
• Long tip forms a fairly straight line
with the LM axis or the proximal
ostial RCA
• Long secondary curve - abut the
opposite aortic wall
• So tip in the coronary artery is not
easily displaced
Multipurpose Guide
• Straight with a single minor bend at the tip
• For RCA bypass graft or a high left main (LM) takeoff
Other catheters
• 3 DRC - Three dimensional right curve - for tortuous, bent
anatomy and posterior or superior take off of RCA
• Arani
 Double angle 90° curve sits on ascending aorta in S
configuration and is therefore useful for RCA with horizontal
take-off & shepherd crook RCA
 Primary and secondary curve provides two contact points on
the opposite side of aorta thus providing tremendous back-up
• XBR and XBRCA - new catheters developed specifically for the
inferior and superior take off of RCA respectively
• El Gamal (EGB) - pre-shaped catheter with improved distal
end-portion for accessing bypass grafts and more precise
access of RCA
• LCB - for left coronary venous bypass grafts. Its tip has 90 º
bend with 70º secondary bend
• RCB - for right coronary venous bypass grafts, its tip and
secondary bends approximate 120º - like a JR catheter with a
shallower tip bend
Guiding Catheter Selection - LCA
Aortic root
•Normal
•Dilated
•Narrow
•JL4
•JL ≥ 5, AL ≥ 2, VL ≥ 4, , XB ≥ 4, EBU ≥ 4
•JL3.5, VL3.5, XB3.0, EBU3.5
Orientation*
•Normal, Anterior
•Posterior
•Superior
•JL, AL, VL, XB, EBU
•AL, VL, XB, EBU
•JL, VL, XB, EBU
Guiding Catheter Selection - RCA
Aortic root
•Normal
•Dilated
•Narrow
•JR4, AL1, AR1
•JR ≥ 5, AL ≥ 2, AR ≥ 2
•JR 3, AL ≤ 0.75
Orientation*
•Normal
•Anterior, Superior
•Inferior
•Shepherd Crook
•Horizontal
•JR, AL, AR
•AL, HS, MP
•MP, AR, JR
•AL, VR, VRSC, ELG, HS, IMA, Champ
•JR, HS, AR, VR
Guiding Catheter Selection - SVG
• RCA graft usual location : Primary – MP
Alternate – JR, AL, RCB, HS, EGB
• RCA graft anterior location : Primary – AL
Alternate – JR, MP, HS
• LCA graft : Primary – JR, HS
Alternate : AL, LCB, MP, EGB (El Gamal)
• LCA graft ant location : Primary – AL, HS
Alternate : JR, LCB, MP
GUIDE CATHETERS FOR
TRANSRADIAL INTERVENTION
Radial vs Femoral Cath course
Choice of Catheters for TR-PCI
• Left coronary artery: down size JL by 0.5
– Judkins left, Amplatz left, Multipurpose, EBU
– Ikari left, El Gamal
• Right coronary artery
– Judkins right, Amplatz right, Amplatz left, Multipurpose, EBU-R
– Ikari right, El Gamal
• Single catheter strategy
– Ikari left, Kimny, Barbeau, Fadajet
TR-PCI of the left coronary artery
TR-PCI of the right coronary artery
Sheathless TRI
Eaucath GC – Asahi, Japan
Virtual 3F - Medikit,Japan
Anchor wire/balloon technique
Guide Extension
Guidezilla catheter
(Boston scientific)
Guideliner catheter
(Vascular solutions)
Summary & Conclusion
• Choice of suitable Guiding Catheters is based on
various patient characteristics & procedural
complexities.
• It is useful to understand the basic principle in
designing various guides for specific requirement
of the case.
• Increasing popularity of TRI is leading to new
technological development in this area.

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Choice of guiding catheters in PCI

  • 1. CHOICE OF GUIDING CATHETERS: TRANS-FEMORAL AND TRANS-RADIAL APPROACH Satyam Rajvanshi
  • 2. • Guide catheters are essential tools for Pecutaneous Coronary Intervention • Understanding construction, design & performance characteristics facilitate their appropriate selection • Selection of Guide catheters seems elementary but makes the difference between a successful and failed PCI procedure
  • 3. Functions of a Guide • Vehicle for contrast injection • Measurement of Pressure • Conduit for wire and device transport • Support for device advancement
  • 4. Guiding vs. Diagnostic catheters A Guide has – Stiffer shaft – Re-enforced construction (3 vs. 2 layers) – Larger internal diameter (ID) – Shorter & more angulated, non tapering atraumatic tip
  • 5. Guide: 3 basic components Hub or ‘Handle’ Shaft – Braided polyurethane or polyethylene. Softens from proximal to distal tip Tip – Soft and atraumatic, varying shapes and sizes Length – usually 100 cms Many catheters have tertiary curve
  • 6. Cross section of catheter Strength Support Flexibility Curve retention Kink resistance Polyurethanene or Polyethylene 1:1 Torque transmission Kink resistance Radiopacity Stainless steel/ Kevlar Large lumen for Device compatibility Lubricious material for smooth device delivery Atraumatic and radiopaque tip PTFE (Teflon)/Silicone
  • 7. DECISIONS IN GUIDE SELECTION
  • 8. Upto 250 shapes available!
  • 9. Factors to consider Goal Factors to consider Co-axial alignment • Coronary or graft anatomy – ostium location; vessel orientation • Access site – Femoral/Radial, Left/Right • Aortic arch configuration, Aortic root size • Body habitus Support • Lesion – Simple / Complex (Long/calcified/Tortuous/Bifurcation/CTO) • Device – type, size, trackeability
  • 11. Larger Guiding Higher bleeding risk but Greater coronary opacification Better torque transmission More passive support More complex PCI possible Smaller Guiding Lower bleeding risk but Less coronary opacification Poorer torque transmission Less passive support Less complex PCI possible
  • 12. Guide size and PCI device Guide size PCI device (s) 5 Fr (1.42-1.50 mm I.D.) POBA Drug coated balloon Scoreflex balloon Most coronary stents Rotablator burr size 1.25 mm Some IVUS catheters Kissing with small profile balloons and .010” wire 6 Fr (1.73-1.80 mm I.D.) Standard angioplasty and stenting Some bifurcation PCI, Kissing with small profile balloons Flextome Cutting balloon 6 Fr Thrombuster/Export catheter Rotablator burr size 1.5 mm IVUS catheters 7 Fr (1.98-2.06 mm I.D.) Simultaneous 2 rapid exchange balloons Simultaneous 2 stent deployment Simultaneous 2 microcatheters 7 Fr Thrombuster Rotablator burr size 1.75 and 2 mm 8 Fr (2.24-2.30 mm I.D.) Simultaneous 2 OTW balloons Rotablator burr size 2.25 mm
  • 13. Factors determining Support • Catheter size – Larger catheter, more support • Co-axial alignment • Catheter support point – Maximum support when angle between point of immediate support and proximal coronary artery is 0 degree – directly opposite the ostia – Larger contact area at support point – more support • Deep Intubation into vessel (‘Active support’) • Physical characteristics of catheter
  • 14. Passive Support • Relies on properties of the shaft and tip to maintain position in the ostium • Support provided by either vascular anatomy or catheter composition/curve shape • Minimal manipulation of the guide is required Active Support • Uses aortic root to form desired curve shape and provide backup support • Relies on active manipulation of guiding catheter to – Obtain stable position – Seat coaxially – Deep seating into the vessel: ostia should be disease-free – Pre-select LAD or LCX
  • 16. Aortic Width: determines curve length
  • 17. Coronary Anatomy Ostial Origins • Left Main – usually antero-inferior and leftward from LCS • LAD - usually anterio-superior from the left main • LCX – usually postero-inferior from the left main • RCA – usually anterior from RCS • SVGs – usually anterior
  • 18. Coronary Anatomy Ostial Variations • Coronary ostial location: – High – Low – Anterior – Posterior • Coronary ostial orientation: – Horizontal – Inferior – Superior
  • 19. Coronary Anatomy Ostial Variations • Coronary ostial location: – High – Low – Anterior – Posterior • Coronary ostial orientation: – Horizontal – Inferior – Superior – Shepherd’s crook (RCA only)
  • 21. • Most common catheters – Judkins – Amplatz – Extra Backup support – EBU (Medtronic) XB (Cordis) Voda, Qcurve (Boston) • Catheters with niche use – Multipurpose – RCA graft, High LM takeoff – IMA cath – LIMA, Superior takeoff RCA or RCA graft – LCB, RCB cath – SVG
  • 22. Judkins catheters • JL – primary (35°) Secondary (180°) and tertiary (35°) curve fitting aortic root anatomy – engages LMCA ostium without much manipulation • JR – requires clockwise rotation to engage RCA 35° 180° 35°
  • 23. Judkins catheters • Aortic width and ostial anatomy determines the curve length JL JR Normal habitus and aortic root size 4.0 4.0 Small habitus and aortic root size 3.5, 3.0 4.0, 3.5 Large habitus and dilated aortic root 5.0, 6.0 4.0, 4.5, 5.0 Superior takeoff RCA 3.0, 3.5 Separate ostia – LAD, LCX Smaller JL for LAD, Larger for LCX
  • 24. Judkins catheters • Short LM selective hooking of LAD/LCX • Toward the LAD - Counter-clockwise rotation • Toward the LCX - Clockwise rotation
  • 25. Limitations of Judkins Guide • As 1° curve is fixed - may not be co-axial with the artery • May be difficult to pass balloons - as catheter makes an angle of 90° with ostium • JL - point of contact on ascending aorta - very high & narrow- ↑ chance of prolapse & dislodgement • JR - no point of contact on Asc Aorta - extremely poor support
  • 26. The Amplatz Guide • Secondary curve rest against the noncoronary posterior aortic cusp • Offers firm platform for advancement of device • Best in the case of a short LM, with downgoing left circumflex artery (LCX) • Tip points slightly downward - higher danger of ostial injury causing dissection
  • 27. Amplatz Guide • Selection of the proper size for an Amplatz guide is essential – Size 1 is for the smallest aortic root – size 2 for normal – size 3 for large roots • Attempts to force engagement of a preformed Amplatz guide that does not conform to a particular aortic root increase risk of complication
  • 28. • If tip does not reach the ostium and keep lying below it - guide is too small • If tip lies above the ostium - guide is too large • When RCA ostium is very high - left Amplatz guide may be used to engage the right ostium
  • 29. Withdrawal of an Amplatz Guide • Must be carefully disengaged from the coronary artery • A simple withdrawal from the vessel can cause the tip to advance farther into the vessel and cause dissection • To disengage - first advance guide slightly to prolapse the tip out of the ostium • Then rotate the guide so that tip is totally out of the ostium before withdrawing it
  • 30. Long tip catheters (Extra Support) • Voda, XB, EBU • Advantages – coaxial intubation – better support & stability due to large area of contact between catheter & contralateral aortic wall – precise control and manipulation – lack of bends - improve advancement of devices, decrease the loss of supportive forces – safety Voda EBU
  • 31. Extra-Back-Up Guide • Long tip forms a fairly straight line with the LM axis or the proximal ostial RCA • Long secondary curve - abut the opposite aortic wall • So tip in the coronary artery is not easily displaced
  • 32. Multipurpose Guide • Straight with a single minor bend at the tip • For RCA bypass graft or a high left main (LM) takeoff
  • 33. Other catheters • 3 DRC - Three dimensional right curve - for tortuous, bent anatomy and posterior or superior take off of RCA • Arani  Double angle 90° curve sits on ascending aorta in S configuration and is therefore useful for RCA with horizontal take-off & shepherd crook RCA  Primary and secondary curve provides two contact points on the opposite side of aorta thus providing tremendous back-up
  • 34. • XBR and XBRCA - new catheters developed specifically for the inferior and superior take off of RCA respectively • El Gamal (EGB) - pre-shaped catheter with improved distal end-portion for accessing bypass grafts and more precise access of RCA • LCB - for left coronary venous bypass grafts. Its tip has 90 º bend with 70º secondary bend • RCB - for right coronary venous bypass grafts, its tip and secondary bends approximate 120º - like a JR catheter with a shallower tip bend
  • 35. Guiding Catheter Selection - LCA Aortic root •Normal •Dilated •Narrow •JL4 •JL ≥ 5, AL ≥ 2, VL ≥ 4, , XB ≥ 4, EBU ≥ 4 •JL3.5, VL3.5, XB3.0, EBU3.5 Orientation* •Normal, Anterior •Posterior •Superior •JL, AL, VL, XB, EBU •AL, VL, XB, EBU •JL, VL, XB, EBU
  • 36. Guiding Catheter Selection - RCA Aortic root •Normal •Dilated •Narrow •JR4, AL1, AR1 •JR ≥ 5, AL ≥ 2, AR ≥ 2 •JR 3, AL ≤ 0.75 Orientation* •Normal •Anterior, Superior •Inferior •Shepherd Crook •Horizontal •JR, AL, AR •AL, HS, MP •MP, AR, JR •AL, VR, VRSC, ELG, HS, IMA, Champ •JR, HS, AR, VR
  • 37. Guiding Catheter Selection - SVG • RCA graft usual location : Primary – MP Alternate – JR, AL, RCB, HS, EGB • RCA graft anterior location : Primary – AL Alternate – JR, MP, HS • LCA graft : Primary – JR, HS Alternate : AL, LCB, MP, EGB (El Gamal) • LCA graft ant location : Primary – AL, HS Alternate : JR, LCB, MP
  • 39. Radial vs Femoral Cath course
  • 40. Choice of Catheters for TR-PCI • Left coronary artery: down size JL by 0.5 – Judkins left, Amplatz left, Multipurpose, EBU – Ikari left, El Gamal • Right coronary artery – Judkins right, Amplatz right, Amplatz left, Multipurpose, EBU-R – Ikari right, El Gamal • Single catheter strategy – Ikari left, Kimny, Barbeau, Fadajet
  • 41. TR-PCI of the left coronary artery
  • 42. TR-PCI of the right coronary artery
  • 43. Sheathless TRI Eaucath GC – Asahi, Japan Virtual 3F - Medikit,Japan
  • 46. Guidezilla catheter (Boston scientific) Guideliner catheter (Vascular solutions)
  • 47. Summary & Conclusion • Choice of suitable Guiding Catheters is based on various patient characteristics & procedural complexities. • It is useful to understand the basic principle in designing various guides for specific requirement of the case. • Increasing popularity of TRI is leading to new technological development in this area.

Editor's Notes

  1. Optimal Position Once the tip of the Amplatz is inside an LM or RCA ostium, the primary and secondary curves should form a closed loop With the tip coaxial to the ostial segment
  2. BL