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Current and future plans
for ELIXIR
Niklas Blomberg, ELIXIR Director
18 December 2013
European Life Sciences Infrastructure for Biological Information
www.elixir-europe.org
ELIXIR’s mission
To build a sustainable
European infrastructure for
biological information,
supporting life science
research and its
translation to:

medicine
environment

bioindustries
society
2
The Challenge in Life Sciences
•
•
•
•
•
•

3

Data
Standards
Tools
Compute
Training
Industry
The Challenge in Life Sciences
•
•
•
•
•
•

4

Data
Standards
Tools
Compute
Training
Industry
A distributed infrastructure to scale with the
challenge
ELIXIR data infrastructure
for Europe’s life science
research sector
ELIXIR Nodes build local
bioinformatics capacity
throughout Europe
ELIXIR Nodes build on
national strengths and
priorities

5
ELIXIR Status
MoU signed:
ECA signed:

Announcing today:
Belgium
6
New building for ELIXIR Hub now open

7
ELIXIR Pilot: Identifying new drug targets

Interoperability of high-resolution protein
data at EMBL-EBI and HPA, Sweden
The Human Protein Atlas portal is a publicly available database with millions of high-resolution images
showing the spatial distribution of proteins in 46 different normal human tissues and 20 different cancer
types, as well as 47 different human cell lines. http://www.proteinatlas.org
8
Acceleration towards sustained operations

• Key objectives:
• In 2014: Build on success of Interim Phase, formal establishment of
Nodes
• In 2015: Start delivering ELIXIR services, sustain BioMedBridges
services
• From 2016 onwards: sustained operations across ELIXIR

9
Industry and Innovation
• Challenge to access and
understand services
• EU wide engagement
programme - Build on
strong local interactions
through Nodes!

• Small companies – Big
Data
• ELIXIR Cloud for SMEs

• EFPIA and IMI

10
ELIXIR Programme

11
A Life-science infrastructure of interoperable and
integrated data-services
Will the improvement we see in an
LPS-challenged mouse translate to
a measurable clinical benefit?

Data interoperability, vocabulary and ontology services

Europe PMC

EGA

Expression Atlas

HPA

Gene Ontology

UniProt

user data

12
BioMedBridges
Ten new biomedical sciences research infrastructures
stronger through common links
• Computational ‘data and service’
bridges between the BMS RIs
• Interoperability between data
and services in the biological,
medical, translational and
clinical domains
• Link basic biological research
data with clinical research and
associated data

13
Future challenges for life-science data services

Distributed infrastructure with >1M users

Scale and
Sustain
funding
Algorithms to data – clouds, research environments…

14
ELIXIR
Safeguarding the results of life science
research in Europe

European Life Sciences Infrastructure for Biological Information
www.elixir-europe.org
17

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Current and future plans for ELIXIR presentation given by Niklas Blomberg, ELIXIR Director at ELIXIR Launch event, 18th December 2013

  • 1. Current and future plans for ELIXIR Niklas Blomberg, ELIXIR Director 18 December 2013 European Life Sciences Infrastructure for Biological Information www.elixir-europe.org
  • 2. ELIXIR’s mission To build a sustainable European infrastructure for biological information, supporting life science research and its translation to: medicine environment bioindustries society 2
  • 3. The Challenge in Life Sciences • • • • • • 3 Data Standards Tools Compute Training Industry
  • 4. The Challenge in Life Sciences • • • • • • 4 Data Standards Tools Compute Training Industry
  • 5. A distributed infrastructure to scale with the challenge ELIXIR data infrastructure for Europe’s life science research sector ELIXIR Nodes build local bioinformatics capacity throughout Europe ELIXIR Nodes build on national strengths and priorities 5
  • 6. ELIXIR Status MoU signed: ECA signed: Announcing today: Belgium 6
  • 7. New building for ELIXIR Hub now open 7
  • 8. ELIXIR Pilot: Identifying new drug targets Interoperability of high-resolution protein data at EMBL-EBI and HPA, Sweden The Human Protein Atlas portal is a publicly available database with millions of high-resolution images showing the spatial distribution of proteins in 46 different normal human tissues and 20 different cancer types, as well as 47 different human cell lines. http://www.proteinatlas.org 8
  • 9. Acceleration towards sustained operations • Key objectives: • In 2014: Build on success of Interim Phase, formal establishment of Nodes • In 2015: Start delivering ELIXIR services, sustain BioMedBridges services • From 2016 onwards: sustained operations across ELIXIR 9
  • 10. Industry and Innovation • Challenge to access and understand services • EU wide engagement programme - Build on strong local interactions through Nodes! • Small companies – Big Data • ELIXIR Cloud for SMEs • EFPIA and IMI 10
  • 12. A Life-science infrastructure of interoperable and integrated data-services Will the improvement we see in an LPS-challenged mouse translate to a measurable clinical benefit? Data interoperability, vocabulary and ontology services Europe PMC EGA Expression Atlas HPA Gene Ontology UniProt user data 12
  • 13. BioMedBridges Ten new biomedical sciences research infrastructures stronger through common links • Computational ‘data and service’ bridges between the BMS RIs • Interoperability between data and services in the biological, medical, translational and clinical domains • Link basic biological research data with clinical research and associated data 13
  • 14. Future challenges for life-science data services Distributed infrastructure with >1M users Scale and Sustain funding Algorithms to data – clouds, research environments… 14
  • 15. ELIXIR Safeguarding the results of life science research in Europe European Life Sciences Infrastructure for Biological Information www.elixir-europe.org
  • 16. 17