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Solway Pharma
Hamid Mukhtar
 Cerebrum
 Cerebellum
 Limbic System
 Brain Stem
 Weighs ~3 pounds
Made of:
• 100 billion Neurons – process and transmit
information
• 1-5 trillion Glial Cells – provides support
1. Adaptability (plasticity) – the brain changes constantly
and grows new neurons potentially at all ages. It is
influenced by our actions, experiences, and the
environment.
2. Integration – brain structures compete and cooperate, the
limbic system can be a gate keeper to learning.
3. Sophistication – the brain is highly complex.
 IMPORTANAT
 Complementary and alternative medicine
(CAM) is defined by the National Center for
Complementary and Alternative Medicine
(NCCAM) as a group of diverse medical
and health care systems, practices, and
products that are not generally considered
part of conventional medicine as practiced
in the west (e.g. the United States).
 Pharmaceuticals 2010, 3, 1426-1445 ISSN 1424-8247
 www.mdpi.com/journal/pharmaceuticals
 NeuroSafe™ Drops have synergetic
effects in different neurological
disease states due to its repertoire of
activity. NeuroSafe™ Drops directly
act upon the Neurotransmitters &
Neurons e.g., GABA so improve the
cognition better.
 NeuroSafe™ Drops has the
following combination of
ingredients:
 Valerian Extract
 Lavandulla Angustifolia
 Moschus (Musk)
 Crocus Sativus
◦ A possible mechanism by which a valerian extract may
cause sedation is by increasing the amount of gamma
aminobutyric acid (GABA, an inhibitory neurotransmitter)
available in the synaptic cleft.
◦ of valerian's historical use as a sedative, anti-convulsant,
migraine treatment and pain reliever, most basic science
research has been directed at the interaction of valerian
constituents with the GABA neurotransmitter receptor
system (Trauner et al. 2008). Valerian extracts and some of
its constituents, mainly valerenic acid, appear to have some
affinity for the GABA receptor. Benke et al. (2009) have
described a specific binding site on GABA receptors with
nM affinity for valerenic acid and valerenol, common
constituents of valerian. Both agents enhanced the response
to GABA at multiple types of recombinant GABA
receptors.
◦ Several animal and human investigations
suggest anxiolytic, mood stabilizer, sedative,
analgesic, and anticonvulsive and
neuroprotective properties for lavender.
These studies raised the possibility of revival
of lavender therapeutic efficacy in
neurological disorders.
◦ lavender extracts inhibits glutamate-induced
neurotoxicity and promotes anti-AchE activity
enhancing the level of Ach in brain.
◦ Lavender also is a strengthens of nervous
system.
 Moschus
◦ Musk has been tested in drug trials on healthy
persons (Jörg, 1825; Leeser, 1961 and Müller, 1995) and
is believed to affect the nervous system, blood
circulation and sex organs, and to have effects on
psychic, sensory and motor functions.
◦ Crocus sativus (Saffron)
recent studies indicate Saffron’s potential as an anti-
cancer agent and memory enhancer.
In a randomized, double blind study, 30 mg of
saffron extract (in capsules) given for 6 weeks
resulted in significant alleviation of depression
compared to those on placebo, and did so without
evident side effects.
 Epilepsy
 C.P. Children
 ADHD (Attention Deficit Hyperactivity Disorder)
 Post Stroke Functional Recovery
 Facial Palsy
 Migraine
 Dementia
 Alzheimer’s Disease
 Depression
 Anxiety
 Insomnia
 Weakness of Memory

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Drops NeuroSafe

  • 2.  Cerebrum  Cerebellum  Limbic System  Brain Stem
  • 3.  Weighs ~3 pounds Made of: • 100 billion Neurons – process and transmit information • 1-5 trillion Glial Cells – provides support 1. Adaptability (plasticity) – the brain changes constantly and grows new neurons potentially at all ages. It is influenced by our actions, experiences, and the environment. 2. Integration – brain structures compete and cooperate, the limbic system can be a gate keeper to learning. 3. Sophistication – the brain is highly complex.
  • 4.
  • 5.
  • 6.
  • 7.
  • 8.  IMPORTANAT  Complementary and alternative medicine (CAM) is defined by the National Center for Complementary and Alternative Medicine (NCCAM) as a group of diverse medical and health care systems, practices, and products that are not generally considered part of conventional medicine as practiced in the west (e.g. the United States).  Pharmaceuticals 2010, 3, 1426-1445 ISSN 1424-8247  www.mdpi.com/journal/pharmaceuticals
  • 9.  NeuroSafe™ Drops have synergetic effects in different neurological disease states due to its repertoire of activity. NeuroSafe™ Drops directly act upon the Neurotransmitters & Neurons e.g., GABA so improve the cognition better.
  • 10.  NeuroSafe™ Drops has the following combination of ingredients:  Valerian Extract  Lavandulla Angustifolia  Moschus (Musk)  Crocus Sativus
  • 11. ◦ A possible mechanism by which a valerian extract may cause sedation is by increasing the amount of gamma aminobutyric acid (GABA, an inhibitory neurotransmitter) available in the synaptic cleft. ◦ of valerian's historical use as a sedative, anti-convulsant, migraine treatment and pain reliever, most basic science research has been directed at the interaction of valerian constituents with the GABA neurotransmitter receptor system (Trauner et al. 2008). Valerian extracts and some of its constituents, mainly valerenic acid, appear to have some affinity for the GABA receptor. Benke et al. (2009) have described a specific binding site on GABA receptors with nM affinity for valerenic acid and valerenol, common constituents of valerian. Both agents enhanced the response to GABA at multiple types of recombinant GABA receptors.
  • 12. ◦ Several animal and human investigations suggest anxiolytic, mood stabilizer, sedative, analgesic, and anticonvulsive and neuroprotective properties for lavender. These studies raised the possibility of revival of lavender therapeutic efficacy in neurological disorders. ◦ lavender extracts inhibits glutamate-induced neurotoxicity and promotes anti-AchE activity enhancing the level of Ach in brain. ◦ Lavender also is a strengthens of nervous system.
  • 13.  Moschus ◦ Musk has been tested in drug trials on healthy persons (Jörg, 1825; Leeser, 1961 and Müller, 1995) and is believed to affect the nervous system, blood circulation and sex organs, and to have effects on psychic, sensory and motor functions. ◦ Crocus sativus (Saffron) recent studies indicate Saffron’s potential as an anti- cancer agent and memory enhancer. In a randomized, double blind study, 30 mg of saffron extract (in capsules) given for 6 weeks resulted in significant alleviation of depression compared to those on placebo, and did so without evident side effects.
  • 14.  Epilepsy  C.P. Children  ADHD (Attention Deficit Hyperactivity Disorder)  Post Stroke Functional Recovery  Facial Palsy  Migraine  Dementia  Alzheimer’s Disease  Depression  Anxiety  Insomnia  Weakness of Memory