VDI and RDS are both desktop virtualization platforms that allow remote access to desktops. With VDI, each user has a dedicated virtual desktop, while with RDS desktops are shared on a common virtual machine. VDI provides more flexibility and customization for each user, while RDS is more cost-effective for shared access since it uses a single virtual machine. Both solutions offer remote access and centralized management capabilities, but their suitability depends on business needs, infrastructure requirements, and number of desktops.