We are into manufacturing of bulk Drug Intermediates and Active Pharmaceutical Ingredients (API). Our core competence is to satisfy our clients who are looking for manufacturers committed to quality and delivery with focus on cost reduction of products. We have recently developed many intermediates and APIs in-house to cater to existing and new customers. Our commitment to quality and customer delight has been a key strength contributing to our growth and success.
2. PROFILE
Started in 1996 as inorganic chemicals manufacturer, we came a long way into manufacturing of high
quality intermediates and APIs. Our commitment to Quality and customer delight has been the strength of
our success and continued growth. We believe in long term relationship with our customers and see our
growth in the growth of our customers. This has made us a tremendously reliable supplier for our customers
looking for great quality, lower cost and on-time delivery.
INFRASTRUCTURE REACTION STRENGTHS
4 Grignard Reaction
UNIT-1 4 Hydrogenation
4 Alkylation
4 Location: Jeedimetla, Hyderabad
4 Halogenation
4 Two Production blocks including a dedicated 4 Hoffmann Reaction
Hydrogenation Block 4 Oxidations
4 20 Reactors (15 SSR and 5 GLR) 4 Reductions
4 Condensation
4 Reactor capacities of 250 L to 3000 L, suitable for 4 Chlorination
both commercial as well as pilot scale activities
4 Dehydrogenation
4 Total capacity of 35 KL 4 Allylic Bromination
4 Manufacturing of advanced intermediates
QUALITY MANAGEMENT SYSTEM
4 Adherence to ICH Q7 guidelines
UNIT-2 4 SOPs
• Change control
4 Location: Ramky Pharma City, Parawada,
• Process validation
Visakapatnam, Andhra Pradesh, India
• Cleaning validation and procedures
4 Ramky Pharma City is a modern industrial estate • Calibration
with common effluent treatment plant and solid • Equipment qualification
waste disposal facility • Deviation and OOS handling
4 Total Area: 12000 sqm • Training
• Self Inspection, etc.,
4 Three Production blocks including a dedicated
Hydrogenation Block
RESEARCH AND DEVELOPMENT
4 Sizes ranging from 500 L to 5000 L
4 Team of 12 scientists undertaking
4 33 Reactors (23 SSR and 10 GLR) • New product development
• Cost reduction
4 Clean room built as per Class 100000 (ISO Class
8) available • Custom synthesis
4 Total reactor capacity: 80 KL.
4 Drug license available. Future plans include
obtaining a WHO GMP and USFDA certification
for this plant.
4 Manufacturing of advanced intermediates and
APIs
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3. TM TM
ISO 9001:2008 CERTIFIED COMPANY
A.R. Life Sciences Pvt. Ltd. ISO 9001:2008 CERTIFIED COMPANY
A.R. Life Sciences Pvt. Ltd.
List of API's LIST OF INTERMEDIATES
THERAPEUTIC S.No. INTERMEDIATE CAS No. Specification API/ END USE
S.No. GENERIC NAME CAS No. SPECIFICATION
USAGE
2-[3-(Cyano-Dimethyl-methyl)-5-methyl-
1 Olanzapine 132539-06-1 IP,USP Anti Psychotic 1 120511-72-0 Purity : NLT 98.00% Anastrozole
phenyl]-2-methyl propionitrile
2 Ondansetron 99614-02-5 USP Anti Emetic
2 4-(2,3-Epoxy propaneoxy)-Carbazole 51997-51-4 Purity : NLT 98.00% Carvedilol
3 Carvedilol 72956-09-3 EP Anti Hypertensive
4 Racecadotril 81110-73-8 EP Anti Diarrhea 3-(N-Methyl-N-Pentyl amino) Purity : NLT 99.00% Ibandronate
3 625120-81-2
propionic acid HCl Assay: 98.00 - 102.00% sodium
5 Oxatomide 60607-34-3 IHS Anti histamine
N-(2-Methyl-5-nitrophenyl)-4-(3-pyridyl)
4 152460-09-8 Purity : NLT 98.00% Imatinib mesylate
-2-pyrimidine Amine
UNDER DEVELOPMENT
N-(5-Amino-2-Methylphenyl)-4-
5 152460-10-1 Purity : NLT 98.00% Imatinib mesylate
(3-pyridyl)-2-pyrimidineamine
1 Risedronate Sodium 105462-24-6 EP Anti Osteoporosis
4-(4-Methyl piperazine-1-yl)methyl Purity : NLT 99.00%
2 Ibandronate Sodium 114084-78-5 IHS Anti Osteoporosis 106261-49-8 Imatinib mesylate
6 benzoic acid di HCl Un-known impurity:
NMT 0.10%
3 Montelukast sodium 158966-92-8 IP,USP Anti asthmatic
4-(4-Methyl piperazine-1-yl)methyl Purity: NLT 99.00%
7 106261-64-7 Imatinib mesylate
benzoyl chloride di HCl
1,2,3,9-Tetrahydro-9-methyl-4
8 27387-31-1 Purity : NLT 98.00% Ondansetron
(H)-Carbazol-4-One
3-[(Dimethylamino)methyl]-1,2,3,9-
Purity : NLT 98.50%
9 tetrahydro-9-methyl-4H- 119812-29-2 Ondansetron
Assay: 96.00-101.00%
carbazol-4-one HCl
2-Amino-5-Methylthiophene- Purity : NLT 99.00% Olanzapine
10 138564-58-6
3-carbonitrile
2-(2-Nitroanilino)-5-methylthiophene 138564-59-7 Olanzapine
11 Purity : NLT 99.90%
-3-carbonitrile (Grade-2)
Purity :NLT 99.00%
4-Amino-2-methyl-10H-thieno-[2,3-b][1,5]- 138564-60-0
12 Un-known impurity: NMT 0.30% Olanzapine
benzodiazepine hydrochloride
Assay: 98.00 - 102.00%
Note: All Transactions are carried out in conformity with patent laws applicable in the buyer's country. Note: All Transactions are carried out in conformity with patent laws applicable in the buyer's country.
Responsibility with respect to third parties' patent rights in a specific country lies exclusively with the buyer. Responsibility with respect to third parties' patent rights in a specific country lies exclusively with the buyer.
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4. TM TM
ISO 9001:2008 CERTIFIED COMPANY
A.R. Life Sciences Pvt. Ltd. ISO 9001:2008 CERTIFIED COMPANY
A.R. Life Sciences Pvt. Ltd.
LIST OF INTERMEDIATES LIST OF INTERMEDIATES
S.No. INTERMEDIATE CAS No. Specification API/ END USE S.No. INTERMEDIATE CAS No. Specification API/ END USE
2-(2-Aminophenylamino)-5- 4-(6-Fluoro-1,2-benzisoxazole-3yl)- Purity : NLT 99.00%
13 873895-41-1 Purity : NLT98.00% Olanzapine 25 84163-13-3 Un-known impurity: NMT 0.10% Risperidone
Methylthiophene-3-Carbonitrile piperidine HCl (Grade-1)
Assay: 98.00- 102.00%
2-(2-Nitroanilino)-5-methylthiophene (+/-)-1-Phenyl-1,2,3,4-Tetrahydro Purity : NLT 99.00% Solifenacin
14 138564-59-7 Purity : NLT 98.00% Olanzapine 26 22990-19-8
-3-carbonitrile (Grade-1) Isoquinoline Assay: 98.00 - 101.00% Succinate
1-(3-chloro propyl)-1,3-dihydro-2H- (S)-1-Phenyl-1,2,3,4-Tetrahydro Purity : NLT 99.00% Solifenacin
15 62780-89-6 Purity : NLT 95.00% Oxatomide 27 118864-75-8
benzimidazol-2-one Isoquinoline (Grade-2) (R)-Isomer :NMT 1.00% Succinate
Purity : NLT 99.00%
9-(Benzyloxy)-3-(2-Chloroethyl)-2- (S)-1-Phenyl-1,2,3,4-Tetrahydro Un-known impurity: NMT 0.10% Solifenacin
Paliperidone 28 118864-75-8
16 147687-17-0 Purity : NLT 98.00% Isoquinoline (Grade-1) (R)-Isomer :NMT 1.00% Succinate
Methyl-4H-Pyrido[1,2-A]Pyrimidin-4-one
3-(2-chloroethyl)-9-hydroxy-2-methyl-6,7,8,9- 29 R-9-(2-Hydroxy Propyl)adenine 14047-28-0 Purity : NLT 97.00% Tenofovir
17 130049-82-0 Purity : NLT 97.00% Paliperidone
tetrahydropyrido[1,2-a] pyrimidin-4-one
Imidazole-1yl-acetic acid Zoledronic
30 87266-37-3 Assay: NLT 98.00%
18 2-Benzyl acrylic acid 5669-19-2 Purity : NLT 98.00% Racecadotril Hydrochloride Acid
UNDER DEVELOPMENT
19 Benzyl glycinate p-toluene sulfonate 1738-76-7 Purity : NLT 97.00% Racecadotril 2,2-(5-bromo methyl-1,3-phenylene)
1 120511-84-4 Under development Anastrozole
di(2-methyl propionitrile)
(1-Hydroxy-2-(3-pyridinyl)ethylidine)-1,
20 105462-24-6 Purity : NLT 99.50% Risedronate sodium 1-(4-(3-chloropropoxy)-3-methoxy
1-bisphosphonic acid 2 58113-30-7 Under development Iloperidone
phenyl)ethanone
Risperidone
21 N-Formyl IsoNipecotic Acid 84163-42-8 Purity : NLT 98.00% Paliperidone N-(4-methylAminobenzoyl)-L-glutamic
Iloperidone 3 2378-95-2 Purity : NLT 98.50% Methotrexate
acid diethyl ester
Risperidone
2,4-Difluoro phenyl (4-Piperidinyl) 2,4-Diamino-6-(hydroxymethyl)-pteridine
22 135634-18-3 Purity : NLT 98.00% Paliperidone 4 73978-41-3 Under development Methotrexate
Methanone Oxime HCl Iloperidone hydrochloride
Purity : NLT 99.00% Risperidone
6-Fluoro-3-(4-piperadinyl)-1,2- Solifenacin
23 84163-77-9 Paliperidone 5 (R)-(-)-3-Quinuclidinol hydrochloride 42437-96-7 Under development
benzisoxazole Assay: 99.00 - 101.00% Iloperidone succinate
4-(6-Fluoro-1,2-benzisoxazole-3yl)- Purity : NLT 99.00% 9-[(R)-2-(Phosphonomethoxy) Propyl]
24 84163-13-3 Risperidone 6 206184-49-8 Under development Tenofovir
piperidine HCl (Grade-2) Assay: 98.00- 102.00% adenine Monohydrate
Note: All Transactions are carried out in conformity with patent laws applicable in the buyer's country. Note: All Transactions are carried out in conformity with patent laws applicable in the buyer's country.
Responsibility with respect to third parties' patent rights in a specific country lies exclusively with the buyer. Responsibility with respect to third parties' patent rights in a specific country lies exclusively with the buyer.
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