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DYSPHAGIA
Kabilan. S
Karthigalakshmi. S
OBJECTIVES
• Anatomy of pharynx and esophagus
• Physiology of swallowing
• Types of dysphagia
• Causes of dysphagia
• Approach to dysphagia
• Management
PHYSIOLOGY OF DEGLUTITION
• GIT motility
Neural : - Parasympathetic nerve fibres
- Sympathetic nerve fibres
ORAL PHASE
PHARYNGEAL PHASE
• Reflex process
• Receptors present at the posterior pharyngeal wall
• UES relaxes
• Contraction of Superior constrictor
• Persistent elevation of soft palate and
tongue
• Vocal cords approximated
• Epiglottis closes the inlet
• Larynx pulled upward and forward
• Relaxation of UES
• Peristaltic wave passes downward
ESOPHAGEAL PHASE
• Primary peristaltic wave
- Contraction of superior constrictor
- 5 to 10 s
• Secondary peristaltic wave
• Tertiary peristatic wave
What is dysphagia?
Difficulty in swallowing, problems with the transit of food or
liquid from mouth to hypopharynx or through esophagus
TYPES
• Based on location : - Oropharyngeal
- Esophageal - Extraluminal
- In the wall of esophagus
- in the lumen
• Based on circumstances : - Structural
- Propulsive
• Based on onset : - Acute
- Chronic
• Based on progression : - Progressive
- Intermittent
OROPHARYNGEAL DYSPHAGIA
STRUCTURAL
ZENKER’S DIVERTICULUM
• Pharyngeal mucosa herniates through Kilian’s
dehiscence
• Due to incoordinated contractions, spasm
• Clinical features : - Dysphagia
- Regurgitation
- Halitosis
NEOPLASM
• Carcinoma of posterior 1/3 of tongue
- Dysphagia
- Bleeding from mouth
- Hot potato voice
- Referred pain in ear
• Carcinoma tonsils / tonsillar fossa
• Carcinoma of posterior and lateral pharyngeal
wall
PROPULSIVE
NEUROGENIC
• Cerebrovascular accident
• Amyotropic lateral sclerosis
• Guillain Barre syndrome
• Parkinson’s disease
MYOGENIC
• Myasthenia gravis
• Poliomyelitis
• Myotonic dystrophy
ESOPHAGEAL DYSPHAGIA
EXTRALUMINAL
• AORTIC ANEURYSM
• THYROID ENLARGEMENT (Malignancy)
• DYSPHAGIA LUSORIA
- Due to aberrant right subclavian artery
- C/f : dysphagia, chest pain, stridor, wheeze
• ROLLING HIATUS HERNIA
- Herniation of stomach fundus/colon/spleen through esophageal opening
- c/f : Abdominal, chest pain
Dysphagia
Palpitations
Shortness of breath
• MEDIASTINAL SWELLINGS
- Primary tumors
- Nodal mass : Lymphoma or Tuberculosis
CAUSES IN THE WALL OF ESOPHAGUS
• CARCINOMA ESOPHAGUS
- 2/3 of lumen should be occluded
- Substernal/abdominal pain
- Anorexia
• CORROSIVE STRICTURE OF ESOPHAGUS
ingestion of alkali
liquefaction, saponification, thrombosis of vessels
fibrosis and stricture
• GASTRO ESOPHAGEAL REFLEX DISEASES (GERD)
- Pathological reflex from the stomach into esophagus
- C/f : Chest pain , pyrosis
Dysphagia
Regurgitation
• ACHALASIA CARDIA
- Dysphagia, regurgitation, weight loss
- Heart burn
• PLUMMER VINSON SYNDROME
- Dysphagia
- Iron deficiency anemia
- Esophageal webs
- Glossitis
- SCHATZKI’S RINGS
• TRACHEO ESOPHAGEAL FISTULA
CAUSES IN THE LUMEN
• Atresia
• Foreign bodies
OROPHARYNGEAL DYSPHAGIA
STRUCTURAL PROPULSIVE
- Zenker’s diverticulum
- Neoplasm
NEUROGENIC MYOGENIC
- CVA
- Amyotropic Lateral Sclerosis
- GBS
- Parkinson’s
- Myasthenia gravis
- Myotonic dystrophy
- Poliomyelitis
ESOPHAGEAL DYSPHAGIA
EXTRALUMINAL IN THE LUMENIN THE WALL
- Aortic aneurysm
- Thyroid enlargement
- Dysphagia Lusoria
- Rolling hiatus hernia
- Mediastinal swelling
- CA esophagus
- Strictures
- GERD
- Achalasia cardia
- PV syndrome
- Congenital anomalies
- Atresia
- Foreign bodies
APPROACH TO DYSPHAGIA
HISTORY
• Age, sex
• Onset
• Progression
• Pain
• Cough
• Past history
EXAMINATION
• General examination
• Mouth and pharynx
• Neck
• Cranial nerves, motor system
INVESTIGATION AND
TREATMENT
Evaluation of a patient with dysphagia
• Proper history
• Hematocrit
• Chest x ray often shows mediastinal mass lesion/foreign body
• Oesophagoscopy:-
once lesion is detected, it is treated accordingly. Biopsy from
lesion, endotheraphy if needed carried out (like foreign body removal,
stricture dilatation, sclerotheraphy)
DIAGNOSTIC PROCEDURES
• Barium swallow:-It may show irregular filling defect or extrinsic
compression
CONTRAST STUDY OF OESOPHAGUS
1.Barium swallow using barium suphate
2.Using water soluble contrast like GASTROGRAFIN
• Indications:-
1.Barium swallow
-Dysphagia due to motility disorder like achalasia cardia, diffuse
esophageal spasm
-Dysphagia due to mechanical causes like carcinoma, benign strictures
and neoplasms, external compression
-Pharyngeal pouch and other diverticula.
-Gastro esophageal reflux disease
• Important findings in barium swallow:-
Achalasia cardia-BIRD BEAK appearance as the esophagus is
dilated above an apparent narrowing at the cardia.
In long standing cases-SIGMOID OESOPHAGUS
• Diffuse oesophageal spasm-CORCKSCREW appearance
• GORD-Shows reflux when done in Trendelenburg's position
• Esophageal carcinoma-irregular steno sing lesion with
shouldering(‘RAT TAIL’) is fluoroscopic finding
• Pharyngeal pouch-demonstration of the pouch
• External compression-indentation of barium column by superior or
posterior mediastinal mass, enlarged left atria as in mitral stenosis
• 2.Water –soluble contrast radiograph
-in suspected pharyngeal perforation
-leaking esophageal anastomosis
• CT scan:- It is very useful to identify the anatomical lesion of the
cause(nodes/tumor/aorta/cardiac cause/congenital).
Extent,spread,nodal status,size and operabilityof tumor also cn be
assessed.
• Oesophageal manometry:
-It is used to measure the function of the lower oesophageal
sphincter(the valve prevents the reflux of gastric acid into oesophagus)
and the muscle of the oesophagus.
-This test will tell your doctor if the oesophagus is able to move
food to your stomach normally.
-It is useful to rule out achalasia cardia/GERD
• 24 hours monitoring:-
-It is ideal and most accurate for GERD
Procedure:-
-small pH probe(transnasal catheter) is passed into oesophagus 5cm
proximal to lower oesophageal sphincter
-probe is connected to digital recorder worn by the patient for 24 hrs
-record is analysed using a computer
If pH<4 more than 4% of total 24 hrs period
Pathological reflux
-It is often assessed by scoring system
-Radio-telemetry pH probes ae used now without any nasal tube
-It is placed and passed on the oesophageal wall using endoscope
• Endosonography:-
-Endoscopic sonography
-can assess site ,layers of the oesophagus,nodes,spread etc
-Different layers are seen as alternating hyperechoic bands and
hypoechoic bands.
Endoscopy is combined with ultrasound to obtain images of the
internal organs(insertion of probe into hollow organ)
-It is performed with the patient sedated
-The endoscope is passed through the mouth and advance through the
oesophagus
-useful method of finding and assessing involvement
or pathology of different layers of esophagus especially in carcinoma
• -It shows all layers clearly and distinctly and so invasion can be
better made Staining using is labelled iodine
• Normal mucosal cells contain glycogen which takes up iodine and so
stains brown
• Carcinoma cells will not take up iodine and so mucosa appears pale
• Ultrasound Abdomen to see abdominal nodes/liver/ascites.
• MRI study
• Oesophagoscopy
Indications:-
Diagnostic
1.To identify the lesion and to take biopsy in carcinoma oesophagus
2.for diagnosing other oesophageal conditions
Therapeutic:-
1.To remove foreign body
2.To dilate stricture
3.To place endostents for inoperable carcinoma oesophagus
4.To inject sclerosants for varices
• TYPES:-
• Rigid osophagascope(Negus type)
-It is done under anesthesia
-Head is extended and head end of the table is tilted upwards,
scope is passed behind the epiglottis and cricoid through the
cricopharyngeal opening.
-this is the most difficult part in oesophagoscopy
-after that negotiating through the oesophagus is easier
-The lesion is identified and biopsy is taken if required.
COMPLICATION:- perforation (at the level of cricopharyngeus is most
common) and bleeding
• Fibreoptic flexible oesophagoscopy
-It can be under local anesthesia
-Reflux and hiatus are well identified
-Stomach also can be visualized
-easy to pass and perforation is unlikely
Drawbacks:
-Tissue taken for biopsy is smaller
-Removal of foreign body is also difficult
• Third space endoscopy:-
-It is a newer method wherein submucosal and intramural spe which
is called as 3rd space(1st being luminal space and 2nd being peritoneal
space)
TREATMENT
Depend on cause –modified heller’s myotomy:-
it is a surgical procedure in which muscles of the cardia(lower
oesophageal sphincter are cut, allowing food and liquids to pass the
stomach.
used to treat achalasia cardia
• Procedure
The patient is put under anesthesia
5or6 small incision are made in the abdominal wall and laparoscopic
instruments are inserted
The myotomy is lengthwise cut along the oesophagus, starting above
the LES and extending down onto the stomach a little way
the oesophagus is made of several layers and the myotomy only cuts
through the outside muscle layers which are squeezing it shut, leaving
the inner mucosal layer intact.
Small risk of perforation is there during myotomy
• OESOPHAGEAL RESECTION:-
it is the surgical removal of oesophagus, nearby lymph nodes and
sometimes a portion of the stomach
TYPES:-
ESOPHAGECTOMY:- it is the surgical removal of oesophagus or
cancerous portion of the esophagus and nearby lymph nodes
ESOPHAGOGASTRETOMY:-It is the removal of lower esophagus and the
upper part of stomach that connects to the esophagus
• OESOPHAGEAL DILATATION:-
Therapeutic endoscopic procedure that enlarges the lumen of the oesophagus.
Types:-
Mercury-weighted bougies
Bougie over guidewire dilators
Pneumatic dilation or balloon dilatation
COMPLICATIONS:-
-Hematemesis
-oesophageal perforation
-Mediastinitis
THANK YOU

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Dysphagia (Surgery) - causes, Types and Approach

  • 2. OBJECTIVES • Anatomy of pharynx and esophagus • Physiology of swallowing • Types of dysphagia • Causes of dysphagia • Approach to dysphagia • Management
  • 3.
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  • 6. PHYSIOLOGY OF DEGLUTITION • GIT motility Neural : - Parasympathetic nerve fibres - Sympathetic nerve fibres
  • 8. PHARYNGEAL PHASE • Reflex process • Receptors present at the posterior pharyngeal wall • UES relaxes • Contraction of Superior constrictor • Persistent elevation of soft palate and tongue • Vocal cords approximated • Epiglottis closes the inlet • Larynx pulled upward and forward • Relaxation of UES • Peristaltic wave passes downward
  • 9.
  • 10. ESOPHAGEAL PHASE • Primary peristaltic wave - Contraction of superior constrictor - 5 to 10 s • Secondary peristaltic wave • Tertiary peristatic wave
  • 11. What is dysphagia? Difficulty in swallowing, problems with the transit of food or liquid from mouth to hypopharynx or through esophagus
  • 12. TYPES • Based on location : - Oropharyngeal - Esophageal - Extraluminal - In the wall of esophagus - in the lumen • Based on circumstances : - Structural - Propulsive • Based on onset : - Acute - Chronic • Based on progression : - Progressive - Intermittent
  • 14. STRUCTURAL ZENKER’S DIVERTICULUM • Pharyngeal mucosa herniates through Kilian’s dehiscence • Due to incoordinated contractions, spasm • Clinical features : - Dysphagia - Regurgitation - Halitosis
  • 15. NEOPLASM • Carcinoma of posterior 1/3 of tongue - Dysphagia - Bleeding from mouth - Hot potato voice - Referred pain in ear • Carcinoma tonsils / tonsillar fossa • Carcinoma of posterior and lateral pharyngeal wall
  • 16. PROPULSIVE NEUROGENIC • Cerebrovascular accident • Amyotropic lateral sclerosis • Guillain Barre syndrome • Parkinson’s disease
  • 17. MYOGENIC • Myasthenia gravis • Poliomyelitis • Myotonic dystrophy
  • 19. EXTRALUMINAL • AORTIC ANEURYSM • THYROID ENLARGEMENT (Malignancy) • DYSPHAGIA LUSORIA - Due to aberrant right subclavian artery - C/f : dysphagia, chest pain, stridor, wheeze
  • 20. • ROLLING HIATUS HERNIA - Herniation of stomach fundus/colon/spleen through esophageal opening - c/f : Abdominal, chest pain Dysphagia Palpitations Shortness of breath
  • 21. • MEDIASTINAL SWELLINGS - Primary tumors - Nodal mass : Lymphoma or Tuberculosis
  • 22. CAUSES IN THE WALL OF ESOPHAGUS • CARCINOMA ESOPHAGUS - 2/3 of lumen should be occluded - Substernal/abdominal pain - Anorexia
  • 23. • CORROSIVE STRICTURE OF ESOPHAGUS ingestion of alkali liquefaction, saponification, thrombosis of vessels fibrosis and stricture
  • 24. • GASTRO ESOPHAGEAL REFLEX DISEASES (GERD) - Pathological reflex from the stomach into esophagus - C/f : Chest pain , pyrosis Dysphagia Regurgitation
  • 25. • ACHALASIA CARDIA - Dysphagia, regurgitation, weight loss - Heart burn
  • 26. • PLUMMER VINSON SYNDROME - Dysphagia - Iron deficiency anemia - Esophageal webs - Glossitis - SCHATZKI’S RINGS
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  • 29. CAUSES IN THE LUMEN • Atresia • Foreign bodies
  • 30. OROPHARYNGEAL DYSPHAGIA STRUCTURAL PROPULSIVE - Zenker’s diverticulum - Neoplasm NEUROGENIC MYOGENIC - CVA - Amyotropic Lateral Sclerosis - GBS - Parkinson’s - Myasthenia gravis - Myotonic dystrophy - Poliomyelitis
  • 31. ESOPHAGEAL DYSPHAGIA EXTRALUMINAL IN THE LUMENIN THE WALL - Aortic aneurysm - Thyroid enlargement - Dysphagia Lusoria - Rolling hiatus hernia - Mediastinal swelling - CA esophagus - Strictures - GERD - Achalasia cardia - PV syndrome - Congenital anomalies - Atresia - Foreign bodies
  • 33. HISTORY • Age, sex • Onset • Progression • Pain • Cough • Past history
  • 34. EXAMINATION • General examination • Mouth and pharynx • Neck • Cranial nerves, motor system
  • 36. Evaluation of a patient with dysphagia • Proper history • Hematocrit • Chest x ray often shows mediastinal mass lesion/foreign body • Oesophagoscopy:- once lesion is detected, it is treated accordingly. Biopsy from lesion, endotheraphy if needed carried out (like foreign body removal, stricture dilatation, sclerotheraphy)
  • 37. DIAGNOSTIC PROCEDURES • Barium swallow:-It may show irregular filling defect or extrinsic compression CONTRAST STUDY OF OESOPHAGUS 1.Barium swallow using barium suphate 2.Using water soluble contrast like GASTROGRAFIN
  • 38. • Indications:- 1.Barium swallow -Dysphagia due to motility disorder like achalasia cardia, diffuse esophageal spasm -Dysphagia due to mechanical causes like carcinoma, benign strictures and neoplasms, external compression -Pharyngeal pouch and other diverticula. -Gastro esophageal reflux disease
  • 39. • Important findings in barium swallow:- Achalasia cardia-BIRD BEAK appearance as the esophagus is dilated above an apparent narrowing at the cardia. In long standing cases-SIGMOID OESOPHAGUS
  • 40. • Diffuse oesophageal spasm-CORCKSCREW appearance
  • 41. • GORD-Shows reflux when done in Trendelenburg's position
  • 42. • Esophageal carcinoma-irregular steno sing lesion with shouldering(‘RAT TAIL’) is fluoroscopic finding
  • 43. • Pharyngeal pouch-demonstration of the pouch • External compression-indentation of barium column by superior or posterior mediastinal mass, enlarged left atria as in mitral stenosis
  • 44. • 2.Water –soluble contrast radiograph -in suspected pharyngeal perforation -leaking esophageal anastomosis
  • 45. • CT scan:- It is very useful to identify the anatomical lesion of the cause(nodes/tumor/aorta/cardiac cause/congenital). Extent,spread,nodal status,size and operabilityof tumor also cn be assessed.
  • 46. • Oesophageal manometry: -It is used to measure the function of the lower oesophageal sphincter(the valve prevents the reflux of gastric acid into oesophagus) and the muscle of the oesophagus. -This test will tell your doctor if the oesophagus is able to move food to your stomach normally. -It is useful to rule out achalasia cardia/GERD
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  • 48. • 24 hours monitoring:- -It is ideal and most accurate for GERD Procedure:- -small pH probe(transnasal catheter) is passed into oesophagus 5cm proximal to lower oesophageal sphincter -probe is connected to digital recorder worn by the patient for 24 hrs -record is analysed using a computer If pH<4 more than 4% of total 24 hrs period Pathological reflux
  • 49.
  • 50. -It is often assessed by scoring system -Radio-telemetry pH probes ae used now without any nasal tube -It is placed and passed on the oesophageal wall using endoscope
  • 51. • Endosonography:- -Endoscopic sonography -can assess site ,layers of the oesophagus,nodes,spread etc -Different layers are seen as alternating hyperechoic bands and hypoechoic bands. Endoscopy is combined with ultrasound to obtain images of the internal organs(insertion of probe into hollow organ) -It is performed with the patient sedated -The endoscope is passed through the mouth and advance through the oesophagus
  • 52. -useful method of finding and assessing involvement or pathology of different layers of esophagus especially in carcinoma • -It shows all layers clearly and distinctly and so invasion can be better made Staining using is labelled iodine • Normal mucosal cells contain glycogen which takes up iodine and so stains brown • Carcinoma cells will not take up iodine and so mucosa appears pale
  • 53. • Ultrasound Abdomen to see abdominal nodes/liver/ascites. • MRI study
  • 54. • Oesophagoscopy Indications:- Diagnostic 1.To identify the lesion and to take biopsy in carcinoma oesophagus 2.for diagnosing other oesophageal conditions Therapeutic:- 1.To remove foreign body 2.To dilate stricture 3.To place endostents for inoperable carcinoma oesophagus 4.To inject sclerosants for varices
  • 55. • TYPES:- • Rigid osophagascope(Negus type) -It is done under anesthesia -Head is extended and head end of the table is tilted upwards, scope is passed behind the epiglottis and cricoid through the cricopharyngeal opening. -this is the most difficult part in oesophagoscopy -after that negotiating through the oesophagus is easier -The lesion is identified and biopsy is taken if required. COMPLICATION:- perforation (at the level of cricopharyngeus is most common) and bleeding
  • 56.
  • 57. • Fibreoptic flexible oesophagoscopy -It can be under local anesthesia -Reflux and hiatus are well identified -Stomach also can be visualized -easy to pass and perforation is unlikely Drawbacks: -Tissue taken for biopsy is smaller -Removal of foreign body is also difficult
  • 58.
  • 59. • Third space endoscopy:- -It is a newer method wherein submucosal and intramural spe which is called as 3rd space(1st being luminal space and 2nd being peritoneal space)
  • 60. TREATMENT Depend on cause –modified heller’s myotomy:- it is a surgical procedure in which muscles of the cardia(lower oesophageal sphincter are cut, allowing food and liquids to pass the stomach. used to treat achalasia cardia
  • 61. • Procedure The patient is put under anesthesia 5or6 small incision are made in the abdominal wall and laparoscopic instruments are inserted The myotomy is lengthwise cut along the oesophagus, starting above the LES and extending down onto the stomach a little way the oesophagus is made of several layers and the myotomy only cuts through the outside muscle layers which are squeezing it shut, leaving the inner mucosal layer intact. Small risk of perforation is there during myotomy
  • 62. • OESOPHAGEAL RESECTION:- it is the surgical removal of oesophagus, nearby lymph nodes and sometimes a portion of the stomach TYPES:- ESOPHAGECTOMY:- it is the surgical removal of oesophagus or cancerous portion of the esophagus and nearby lymph nodes ESOPHAGOGASTRETOMY:-It is the removal of lower esophagus and the upper part of stomach that connects to the esophagus
  • 63.
  • 64. • OESOPHAGEAL DILATATION:- Therapeutic endoscopic procedure that enlarges the lumen of the oesophagus. Types:- Mercury-weighted bougies Bougie over guidewire dilators Pneumatic dilation or balloon dilatation COMPLICATIONS:- -Hematemesis -oesophageal perforation -Mediastinitis
  • 65.