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PCWP - LVEDP Pulmonary capillary wedge pressure (PCWP) performs poorly in predicting left-ventricular end-diastolic pressure (LVEDP) Scott D. Halpern, M.D., Ph.D. Division of Pulmonary, Allergy, and Critical Care Medicine, Hospital of the University of Pennsylvania ,[object Object],[object Object],[object Object],Mean Bias: -3.9  Limits of Agreement: -15.8 to 8.0 Average of PCWP & LVEDP Bland – Altman Plot ,[object Object],[object Object],[object Object],PCWP Discriminating LVEDP ≥ 15 vs. < 15 PCWP = 15 Sens 66%, Spec 91% PCWP = 10 Sens 91%, Spec 53% PCWP = 20 Sens 39%,  Spec 97% AUROC = 0.90 using LVEPD  ≥ 10 AUROC = 0.81 using LVEPD  ≥ 20 AUROC = 0.86 using LVEPD ≥ 15   ,[object Object],[object Object],[object Object],[object Object],Background ,[object Object],[object Object],Objectives ,[object Object],[object Object],[object Object],[object Object],Methods ,[object Object],[object Object],[object Object],Results ,[object Object],[object Object],[object Object],Conclusions Implications

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