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Diagnosis of pregnancy




 DR: MANAL BEHERY
Zagazig University , Egypt
Principles of diagnosis

In the majority of women, the diagnosis of
 pregnancy is usually straightforward based on a
 history of amenorrhea and a positive pregnancy test.

women with irregular periods or irregular vaginal
 bleeding , the diagnosis of pregnancy is more
 complex.
 Other symptoms of pregnancy may alert the
 clinician to the possibility of pregnancy.
Symptoms of pregnancy:

Amenorrhoea:            HOWEVER
Pregnancy may occur during period of lactation
 amenorrhea.
Slight bleeding early in pregnancy (threatened
 abortion) may be considered by the patient as menses .

Hartman's symptoms: slight bleeding occurs at time of
 menstruation
Symptoms of pregnancy:

Morning sickness: nausea, rarely vomiting
 confined to morning
Increased frequency of micturition.
Enlargement of the breast and sensation of
 heaviness.
Easy fatiguability and tendency to sleep.
Emotional changes e.g. change of the
 appetite:
In the second and third trimesters


1-Abdominal enlargement
2-Quickening
 -1st perception (sensation) of fetal movements by
 the lady

-PG (18-20 weeks), MP (16-18 weeks)
Signs of pregnancy
Chloasma gravidarum


Butterfly face
pigmentation
Breast signs


Increased pigmentation of the nipple and lry areola.
Appearance of Montgomery tubercle in
              the areola




dilated sebaceous glands
Abdominal stria
Linea nigra
- Abdominal signs
   Inspection:-
2- Palpation:
Auscultation:

 Auscultation of FHS as early as 10-12 weeks by
 sonicade
Auscultation of FHS as early as 20-24 weeks by
 Pinard stethoscope
Auscultation of umbilical souffle as early as 20-24
 weeks.
Auscultation of uterine souffl
Pregnancy tests:
                  Principle:
Detection of
HCG in the
 urine or
serum .
1- Urinary pregnancy test:


Classically it becomes +Ve 7- 10 day after 1st missed
 period

 Commercial testing kits are available that are
 sensitive to 25 iu/L in urine.

By the time the mother has missed her first
 menstrual period, her hCG levels are around 100
 iu/L.
Serum pregnancy test:

Classically it becomes +Ve 5- 7 days before 1 st
 missed period

A quantitative serum HCG assay level of > 5 iu/L
 will usually denote a pregnancy.

With a normal intrauterine pregnancy, the hCG
 level doubles approximately every 36-48 hours.
Tran abdominal US
Transvaginal ultrasound ( TVS):
12 WEEKS GESTATION

CROWN RUMP
 LENGTH(CRL)
2ND TRIMESTER
Sure signs of pregnancy:

Inspection of fetal parts as early as 20th week.
 -Inspection of fetal movements as early as 20th
 week.
Palpation of fetal movements as early as 20th week.
 -Palpation of fetal parts as early as 20th week.
Sure signs of pregnancy

-Auscultation of FHS at 10-12 weeks by sonicade


 Investigations: Visualization of fetal parts by
 ultrasound
ANTENATAL CARE
Definition

Antenatal care refers to the care that is
 given to an expected mother from time
 of conception is confirmed until the
 beginning of labor

It is a preventative cost effective
 service
GOALS

1-Ensure mother health.


2- Ensure delivery of a healthy infant.


3-Anticipate problem


4- Diagnose problem early.
Objectives

1-Early detection and if possible, prevention of
complications of pregnancy.



2-Educate women on danger and emergency signs &
symptoms.

3-Prepare the woman and her family for childbirth

4- Give education & counseling on
family planning
Schedual of antenatal care:

  Medical check up every four weeks up to 28
  weeks gestation,

  Every 2 weeks until 36 weeks of gestation

  Every week until delivery

  An average 7-11 antenatal visits/pregnancy

  More frequent visits may be required if
  complications arise.
On first antenatal visit

1-First : Confirm pregnancy by
 pregnancy test or US.

2-History


3-Physical examination


4-investigation
History
Personal history


Menstrual history
Obstetrical history
Family history
Medical and surgical history
History of present pregnancy
Menstrual history

- Ask about
- 1-Last menstrual period (LMP).


- 2-Regularity and frequency of menstrual cycle.
- 3-Contraception method used .
- 4-Calculate expected date of delivery (EDD)
   as
1st day of LMP −3 months +7 days, and change the
   year.
Obstetric History

  Gravidity? Parity? abortion, and living
  children.
 Weight of infant at birth & length of
  gestation.
 Type of delivery, location of birth, and
  type of anesthesia.
 Maternal or infant complications.
Medical and surgical history:

1-Chronic conditions : as diabetes mellitus,
  hypertension, and renal disease ,cardiac disease.

2-Prior operation: as cesarean section, genital
 repair, and cervical cerclag.
3-Allergies, and medications.

4-Accidents involving injury of the bony pelvis
History of present pregnancy

   History suggesting e.g. Diabetes,
    hypertension and ante partum hemorrhage.

   Ask about episodes of fever or chills

 Ask about pain or burning sensation on
  urination.
 Abnormal vaginal discharge, itching at the
  vulva or if partner has a urinary problem.
Emergency symptoms
Vaginal bleeding
Severe abdominal ,epigastric, or pelvic pain
Severe headache with visual disturbance
Persistent vomiting
Unconscious/Convulsion
Severe difficulty in breathing
Fever, chills , dysurea
Absent fetal movement
Assessment and physical examination
Weight measurement

Maternal height and weight
 measurements to determine body mass
 index(BMI).

Maternal weight should be
 measured at each
antenatal visit




Check for pallor or anemia.


1-Look for palmar pallor.

2-Look for conjunctival
   pallor

3-Count respiratory rate in
   one minute.
Blood pressure measurement

    Measure BP in sitting position.

    If diastolic BP is 90 mm Hg or
    higher repeat measurement
    after 6 hour rest.

    If diastolic BP is still 90 mm
    Hg or higher ask the woman if
    she has:
•     Severe headache
•     Blurred vision
•     Epigastric pain

    Check urine for protein.
Investigations

Get baseline on the first or following the first
   visit.
      Hemoglobin, blood type
      Urine analysis
      VDRL or RPR to screen for
      syphilis
      Hepatitis B surface antigen To
      detect carrier status or active
      disease
At each visit
At each visit
1-Questions about fetal movement


2-Ask for danger signs during this pregnancy


3-Ask patient if she has any other concerns
Symphysis Fundal hieght

                 • LMP plus 280 days

                 • Add 7 days, subtract
                  3 months
                 • MacDonald's Rule
                  (cm = weeks)
At third trimester


Do
Leopold’s exam
Provide advice on


1.Diet and weight gain
2.Medication
3.Avoid Radiation exposure
4.Self-care during pregnancy
5.Minor complaints.
6. Family planning Breastfeeding
7.Birth place preparation and anticipation of
   complication& Emergency situations.
Diet in pregnancy:

 
Total caloric intake increase to 300 kcal /day due to 
 15% increase in BMR .
Diet show contain 20%Protein(better from animal 
 source), 30% fat ,and 50% carbohydrates .

Sufficient fluids should be available.
Supplementation

1-Folic acid 0.4 mg tab daily 
2- iron (ferrous sulphate or gluconate )300 mg/daily
 3- Ca 1200mg /daily 
4-


• -Those with a normal balanced diet 
• probably don’t need extra vitamins
Weight gain in pregnancy:

There is a slight loss of pounds during early 
    pregnancy if the patient experiences much nausea 
    and vomiting. 

Weight gain of 2 to 4 lbs(0,5-1 kg) by the end of the 
    first trimester. 

Gain of 1 lb(0.5)/ per wk is expected during the 
    second and third trimesters.
 
Monitoring of weight gain should be done in 
    conjunction with close monitoring of BP. 
Medications During Pregnancy
          • Antibiotics - some OK, some not

          • Local anesthetics - OK

          • Local with epinephrine - not OK

          • Aspirin - not OK

          • Immunizations - some are OK, 
           some are not
          • Antimalarial - some OK, some are 
           not
          • Narcotics - OK except for addiction 
           issue
Case Study 
Case Study 

A 35-year-old G2 P1+0 woman is seen for her first 
 prenatal visit. 
Based on her LMP, she is at 15 weeks’ gestation. 
She has no complaints, and no significant medical 
 history.
 She denies dysuria or urinary urgency.
Her surgical history is remarkable
Her last delivery was a vaginal delivery and was 
 uncomplicated
 On examination

Her blood pressure (BP) is 100/65 mm Hg


heart rate (HR)90 (bpm),


 respiratory rate (RR) 12,temperature 98°F (36.6°C), 
weight 70KG.


general physical examination is normal
Abdominal examination

 Her abdomen is non tender 
Fundal height is at the level ofthe umbilicus.
 Fetal heart tones are 140 bpm. 
Her extremities are without edema.
Prenatal laboratories

CBC: Hgb 10.0 g/dL ,Plt 150,000 WBC 8,000
Rubella: nonimmune 
Hepatitis B surface antigen: positive
Blood type: O, Rh negative 
UC&S: 10,000 cfu/mL of group Bstreptococcus
Gonorrhea assay: negative Chlamydia assay: 
 negative
Questions
➤ What items should be listed on the problems list?


➤ What is your next step for the problems listed?


➤ What other testing should be recommended to the 
 patient?
Problem List:

Advanced maternal age 35 Y or greater at EDD
fundal height at umbilicus corresponds to 20 weeks)
 Mild microcytic anemia (Hgb < 10.5)
 Hepatitis B surface antigen (HBsAg) positive
 Rh-negative blood type
 Urine culture with GBS 10,000 cfu/mL,
Rubella nonimmune
Next Steps:

1. AMA—genetic counseling


2. Size/dates—fetal ultrasound to assess GA, 
 multiple gestation
3. Anemia—therapeutic trial of iron


4. HBsAg positive—check liver function tests, and 
 hepatitis B serology toassess for active hepatitis 
 versus chronic carrier status
Next step

5. Rh negative Rhogam at 28 weeks and at delivery if 
 the baby proves to be Rh positive

6. Urine culture with GBS—treat with ampicillin and 
 re-culture urine, peni-cillin IV prophylaxis in labor

7. Rubella status—vaccinate postpartum
Other tests recommended to patient

consider early diabetic screen
Thank you 

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Diagnosis of pregnancy &antenatal care for undergraduate

Editor's Notes

  1. to detect problems that might affect the woman&apos;s pregnancy and require additional care - routinely screen for anemia, hypertension, HIV, syphilis and diabetes mellitus. Recognize other problems that may complicate pregnancy: malnutrition and tuberculosis, vaginal bleeding, vaginal discharge, fetal distress and abnormal fetal position after 36 weeks Danger and emergency signs: Fever, vaginal bleeding, headache and blurring of vision, severe abdominal pain, convulsion, severe difficulty of breathing Birth and emergency plan
  2. The World Health Organization (WHO) recommends giving ferrous sulfate 320 milligrams (60 mg of elemental iron) twice a day to all pregnant women. If the woman’s hemoglobin is 8 gm or less at any visit, increase her iron supplementation to three times a day for the entire pregnancy. If ferrous sulfate is not available, give an equal amount of elemental iron in another iron preparation.
  3. Distinguish chronic hypertension, pre-eclampsia and severe pre-eclampsia. These patients should be referred to the doctor
  4. Nutrition – what food to eat and what foods to avoid during pregnancy. Self-care during pregnancy – the importance of hygiene Discuss breastfeeding and benefits during the prenatal consultation. Explain the danger signs and the signs of labor.