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ECG Criterias for 
Chamber Enlargement
Left Ventricular Hypertrophy
Pressure overload pattern
Volume overload pattern
• Sokolow-Lyon voltages 
• SV1 + R V5,6 > 3.5 mV 
Sensitivity 22% 
Specificity 100 % 
• R aVL > 1.1 mV 
• R V5,6 > 2.6 mV
• Romhilt-Estes point score system 
– Any limb lead R wave or S wave > 2.0 mV (3 points) 
or SV1 or SV2 ≥ 3.0 mV (3 points) 
or RV5 to RV6 ≥ 3.0 mV (3 points) 
– ST-T wave abnormality, no digitalis (3 points) 
ST-T wave abnormality, digitalis therapy (1 point) 
– Left atrial abnormality (3 points) 
– Left axis deviation ≥ −30 degrees (2 points) 
– QRS duration ≥ 90 msec (1 point) 
– Intrinsicoid deflection in V5 or V6 ≥ 50 msec (1 point) 
• Probable =4, Definite > = 5 
• Sn 35-55 %, Specificity 85-95 %
• Cornel Voltage criteria 
–SV3 + R aVL ≥ 2.8 mV (for men) 
–SV3 + R aVL >2.0 mV ( women) 
–Sensitivity 42% 
–Specificity 96%
• Cornell voltage duration measurement 
– QRS duration X Cornell voltage > 2,436 mm-sec 
( + 8mm if female ) 
– QRS duration X sum of voltages in all leads > 1,742 
mm-sec 
– Sn 51 % and specificity of 95 % 
– Accurate in obese
• Cornell Regression equation 
– Risk of LVH = 1/(1+ e−exp) 
– For subjects in sinus rhythm, 
– exp = 4.558 − 0.092 (SV3 + RaVL) − 0.306 TV1 − 
0.212 QRS − 0.278 PTFV1 − 0.559 (gender) 
– PTF is the area under the P terminal force in lead 
V1 (in mm-sec) 
– gender = 1 for men and 2 for women. 
– LVH is diagnosed present if exp < −1.55
• LVH : total QRS voltage in all 12 leads > 175 
mm 
• LVH : R in V6 = > V5 
• Gertsch index : S III + max ( R+S) in any 
precardial lead > 3.0 mV . valid even if LAFB 
• Lewis score: R I + S III > 17 mm
More sensitive : LVH in HTN : sum of the QRS voltage of 12 ECG 
leads >120 mm
90 % of LBBB have LVH 
A left atrial P-wave abnormality 
QRS duration > 155 ms 
SOURCE: Hurst 12/e Kafka, Burggraf, Milliken
SOURCE : hurst 12/e Gertsch, Theler, Foglia
RBBB and LVH 
• RBBB decreases sensitivity of precardial voltage criteria 
• LAA can be useful 
• Point score system can be useful 96 % specific
Right Ventricular 
hypertrophy
R’ > 15 mm in RBBB 
Cabrera index > 0.5 
R in V1/(R v1 + s v1)
Sokolow Lyon criteria for RVH: 
– R V1 + S V5, V6 > 10.5 mm 
– R V1 > 7 mm 
– R in aVR > 5mm 
– S V1 < 2mm
• Butler leggett formula : 
RVH : Anterior (R or R’ in v1 or v2) + Right 
(deepest S in I or v6) – Posterolateral 
( S in V1) => 0.7mV ( Sn 34% and Sp 95%)
RVH Morphology 
1. Precardial Voltage changes 
2. ST T changes over RV 
3. Delayed onset of intrinsicoid deflection 
4. normal QRS duration 
5. RAD
CHOU Types of RVH 
• Type A: Typical RVH 
tall R in V1 , Prominent S in V5, V6 
• Type B: Incomplete RBBB pattern( ASD, RHD ) 
R in V1 >0.5 mV with R/S >1, Normal 
QRS in V5, V6 
• Type C: Chronic Lung Disease 
(rS V1, V2 and RS in V5, V6 precardial 
leads) 
– ECG changes due to both RVH + anatomical shift 
of heart
• RAD and Clockwise rotation is very common 
in Type A RVH compared to B & C
The signs of acute RV overload : 
• Change in the ÂQRS (>30° to the right) 
• Transient negative T waves 
• SI, QIII TIII pattern (McGinn-White pattern) in 
the frontal plane and an RS or rS pattern in V6 
• Appearance of a complete right bundle-branch 
block morphology often with ST-segment 
elevation 
• S1Q3T3 pattern occurs in only about 10% PE 
PPV 23- 69%
Chronic Obstructive Pulmonary Disease 
• reduced amplitude of the QRS complex 
• right axis deviation in the frontal plane 
• delayed transition in the precordial leads 
• Evidence of true RVH 
– (1) RAD > 110 degrees 
– (2) deep S waves in the lateral precordial leads 
– (3) an S1Q3T3 pattern
Biventricular hypertrophy 
• Diagnostic voltage criteria for both ventricles 
• Delayed intrinsicoid delection over both 
ventricles 
• Repolarization changes over both 
• LVH with RAD of QRS 
• LVH with RAE 
• Deep S in LVH 
• LVH with clock wise rotation of precardial 
morphology
Biventricular hypertrophy 
• LAD with counterclockwise rotation in RVH 
• Large equiphasic QRS in midprecardial leads 
>6mm( Katz wachtel sign) 
• Tall R in Left precardial leads + small s in V1 or 
inverted t waves in right precardial leads
Atrial Enlargement
RAA 
• Q waves (especially qR patterns) in the right 
precordial leads (100 % specific) 
• low-amplitude QRS complexes (<0.6 mV) in 
lead V1 with a threefold or greater increase in 
lead V2 (90 % specific) 
• Severe RAE  prominent terminal negativity 
in V1 ( Pseudo LAE pattern ) 
• Early terminal negativity of P V1 (< 0.03 s)
AF – LAE present if f wave > 1mm in V1
LAE Criteria Sensitivity specificity 
Prolonged P wave duration > 120 msec in lead II 33 88 
Prominent notching of P wave, usually most obvious in 
lead II, with interval between notches of 0.40 msec (P 
mitrale) 
15 100 
Ratio between the duration of the P wave in lead II and 
duration of the PR segment > 1.6 Macruz index 
31 64 
Increased duration and depth of terminal- negative 
portion of P wave in lead V1 (P terminal force) so that 
area subtended by it > 0.04 mm-sec Morris index 
69 93 
Terminal negative deflection in V1 > 0.1 mV 60 93 
duration > 0.04 s 83 80 
Leftward shift of mean P wave axis to between −30 and 
−45 degrees
Biatrial Enlargement
ECG diagnosis of  chamber enlargement

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ECG diagnosis of chamber enlargement

  • 1. ECG Criterias for Chamber Enlargement
  • 5.
  • 6. • Sokolow-Lyon voltages • SV1 + R V5,6 > 3.5 mV Sensitivity 22% Specificity 100 % • R aVL > 1.1 mV • R V5,6 > 2.6 mV
  • 7. • Romhilt-Estes point score system – Any limb lead R wave or S wave > 2.0 mV (3 points) or SV1 or SV2 ≥ 3.0 mV (3 points) or RV5 to RV6 ≥ 3.0 mV (3 points) – ST-T wave abnormality, no digitalis (3 points) ST-T wave abnormality, digitalis therapy (1 point) – Left atrial abnormality (3 points) – Left axis deviation ≥ −30 degrees (2 points) – QRS duration ≥ 90 msec (1 point) – Intrinsicoid deflection in V5 or V6 ≥ 50 msec (1 point) • Probable =4, Definite > = 5 • Sn 35-55 %, Specificity 85-95 %
  • 8. • Cornel Voltage criteria –SV3 + R aVL ≥ 2.8 mV (for men) –SV3 + R aVL >2.0 mV ( women) –Sensitivity 42% –Specificity 96%
  • 9. • Cornell voltage duration measurement – QRS duration X Cornell voltage > 2,436 mm-sec ( + 8mm if female ) – QRS duration X sum of voltages in all leads > 1,742 mm-sec – Sn 51 % and specificity of 95 % – Accurate in obese
  • 10. • Cornell Regression equation – Risk of LVH = 1/(1+ e−exp) – For subjects in sinus rhythm, – exp = 4.558 − 0.092 (SV3 + RaVL) − 0.306 TV1 − 0.212 QRS − 0.278 PTFV1 − 0.559 (gender) – PTF is the area under the P terminal force in lead V1 (in mm-sec) – gender = 1 for men and 2 for women. – LVH is diagnosed present if exp < −1.55
  • 11. • LVH : total QRS voltage in all 12 leads > 175 mm • LVH : R in V6 = > V5 • Gertsch index : S III + max ( R+S) in any precardial lead > 3.0 mV . valid even if LAFB • Lewis score: R I + S III > 17 mm
  • 12. More sensitive : LVH in HTN : sum of the QRS voltage of 12 ECG leads >120 mm
  • 13. 90 % of LBBB have LVH A left atrial P-wave abnormality QRS duration > 155 ms SOURCE: Hurst 12/e Kafka, Burggraf, Milliken
  • 14. SOURCE : hurst 12/e Gertsch, Theler, Foglia
  • 15. RBBB and LVH • RBBB decreases sensitivity of precardial voltage criteria • LAA can be useful • Point score system can be useful 96 % specific
  • 17. R’ > 15 mm in RBBB Cabrera index > 0.5 R in V1/(R v1 + s v1)
  • 18.
  • 19. Sokolow Lyon criteria for RVH: – R V1 + S V5, V6 > 10.5 mm – R V1 > 7 mm – R in aVR > 5mm – S V1 < 2mm
  • 20. • Butler leggett formula : RVH : Anterior (R or R’ in v1 or v2) + Right (deepest S in I or v6) – Posterolateral ( S in V1) => 0.7mV ( Sn 34% and Sp 95%)
  • 21. RVH Morphology 1. Precardial Voltage changes 2. ST T changes over RV 3. Delayed onset of intrinsicoid deflection 4. normal QRS duration 5. RAD
  • 22. CHOU Types of RVH • Type A: Typical RVH tall R in V1 , Prominent S in V5, V6 • Type B: Incomplete RBBB pattern( ASD, RHD ) R in V1 >0.5 mV with R/S >1, Normal QRS in V5, V6 • Type C: Chronic Lung Disease (rS V1, V2 and RS in V5, V6 precardial leads) – ECG changes due to both RVH + anatomical shift of heart
  • 23. • RAD and Clockwise rotation is very common in Type A RVH compared to B & C
  • 24. The signs of acute RV overload : • Change in the ÂQRS (>30° to the right) • Transient negative T waves • SI, QIII TIII pattern (McGinn-White pattern) in the frontal plane and an RS or rS pattern in V6 • Appearance of a complete right bundle-branch block morphology often with ST-segment elevation • S1Q3T3 pattern occurs in only about 10% PE PPV 23- 69%
  • 25. Chronic Obstructive Pulmonary Disease • reduced amplitude of the QRS complex • right axis deviation in the frontal plane • delayed transition in the precordial leads • Evidence of true RVH – (1) RAD > 110 degrees – (2) deep S waves in the lateral precordial leads – (3) an S1Q3T3 pattern
  • 26. Biventricular hypertrophy • Diagnostic voltage criteria for both ventricles • Delayed intrinsicoid delection over both ventricles • Repolarization changes over both • LVH with RAD of QRS • LVH with RAE • Deep S in LVH • LVH with clock wise rotation of precardial morphology
  • 27. Biventricular hypertrophy • LAD with counterclockwise rotation in RVH • Large equiphasic QRS in midprecardial leads >6mm( Katz wachtel sign) • Tall R in Left precardial leads + small s in V1 or inverted t waves in right precardial leads
  • 29.
  • 30.
  • 31. RAA • Q waves (especially qR patterns) in the right precordial leads (100 % specific) • low-amplitude QRS complexes (<0.6 mV) in lead V1 with a threefold or greater increase in lead V2 (90 % specific) • Severe RAE  prominent terminal negativity in V1 ( Pseudo LAE pattern ) • Early terminal negativity of P V1 (< 0.03 s)
  • 32. AF – LAE present if f wave > 1mm in V1
  • 33. LAE Criteria Sensitivity specificity Prolonged P wave duration > 120 msec in lead II 33 88 Prominent notching of P wave, usually most obvious in lead II, with interval between notches of 0.40 msec (P mitrale) 15 100 Ratio between the duration of the P wave in lead II and duration of the PR segment > 1.6 Macruz index 31 64 Increased duration and depth of terminal- negative portion of P wave in lead V1 (P terminal force) so that area subtended by it > 0.04 mm-sec Morris index 69 93 Terminal negative deflection in V1 > 0.1 mV 60 93 duration > 0.04 s 83 80 Leftward shift of mean P wave axis to between −30 and −45 degrees