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Wound and wound
infection
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 Wound – is injury with disruption of
skin or mucous membranes and
possible underlying tissues injuries
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Classification of wounds
 1. Depending on the cause
 - surgical (aseptic)
 - accidental (casual)
 - battle (wartime)
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 2. According to the character:
 - incised (knife, blade)
 - stab (bayonet, awl)
 - chopped (axe, sabre)
 - contused (blunt tools)
 - crushed (blunt tools)
 - lacerated (traction with sharp retractor)
 - bite (animals, human)
 gunshot (wound canal, primary traumatic
necrosis, concussion area)
 - poisoned (spiders, snakes)
 combined
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 3. Depending on the presence of infection:
 - aseptic
 - infected
 - purulent
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 4. In relation to the bodily cavities:
 - penetrating
 - non-penetrating
 5. Depending on the presence of
complications:
 - non-complicated
 - complicated
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Clinical manifestation
 Pain
 Bleeding
 Gaping
 Dysfunctions
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Complications of wounds
 Bleeding with hemorrhagic shock
 Injury of vital organs
 Infection
 Longterm consequences (contractures,
organs insufficiency etc)
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Healing of the wound:
 by primary intention
 by secondary intention
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Wound healing phases:
 Inflammatory phase
 Proliferative phase
 Remodeling phase
 Epithelialization
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Inflammatory phase
 In the inflammatory phase, bacteria and are
debris are phagocytosed and removed, and
factors are released that cause the
migration and division of cells involved in the
proliferative phase.
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Basic signs of inflammation
 Redness (rubor)
 Swelling (tumor)
 Pain (dolor)
 Increase in local temperature (calor)
 Functions disorder
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Proliferative phase
 The proliferative phase is characterized by
angiogenesis, collagen deposition,
granulation tissue formation,
epithelialization, and wound contraction.
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Remodeling phase
 In the maturation and remodeling phase,
collagen is remodeled and realigned along
tension lines and cells that are no longer
needed are removed by apoptosis.
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Epithelialization
 In epithelialization phase, epithelial
cells migrate across the tissue to form
a barrier between the wound and the
environment.
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Factors affecting wound healing
 A. General factors:
– age
– debilitation results in malnutrition
– diabetic patients
– jaundice, uremia
– cytotoxic drugs and malignancy
– generalized infection
– Corticosteroides
 B. Local factors:
– poor blood supply
– local infection
– haematoma
– faulty technique of wound closure
– tension while suturing
– oxygen
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First aid
 Haemostasis (temporary or definitive)
 Cleaning of surrounding skin with an
antiseptic solution
 Application of aseptic dressing on the
wound
 Transport immobilization
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Primary surgical wound debridement
 Early (within 24 hours)
 Delayed (within 24-48 hours)
 Late (more than 48 hours after injury)
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Primary surgical wound debridement
 Main purpose – prophylaxis of wound
infection development
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Primary surgical wound debridement
involves:
 Excision of wound edges, bases and walls
up to the intact tissues
 Removing all non-vital tissues, foreign
bodies, clots of blood
 Repair of blood vessels, nerves, muscles
 Suturing the wound
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Wound closure
or wound suturing:
 Primary suturing
 Wound excision and primary suturing of skin
 Wound excision and delayed primary suture
 Secondary suturing
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Secondary surgical wound
debridement:
 Main purpose – surgical treatment of
purulent wound
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Secondary surgical wound
debridement involves:
 Wide long incisions
 Opening all pockets in wound and combined
in one cavity
 Excision all necrotic tissues
 Insertion of drainage tubes, washing
systems for permanent cleaning the wound
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Treatment of purulent wounds
 1. In hydration phase:
 - removing pus
 - washing with antiseptic solutions (H2O2,
furacilin, KMnO4)
 - bandages with hypertonic solutions
 - proteolytic enzymes
 - laser, ultrasound cavitation
http://mbbshelp.com
Treatment of purulent wounds
 2. In dehydration phase
 - ointments with antibiotics
 - ointments with substances, which stimulate
reparative processes in wound (solcoseril,
actovegin, metyluracil)
 - physiotherapy
 - secondary sutures
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Thank you for your attention
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Wound and wound infection

  • 2.  Wound – is injury with disruption of skin or mucous membranes and possible underlying tissues injuries http://mbbshelp.com
  • 3. Classification of wounds  1. Depending on the cause  - surgical (aseptic)  - accidental (casual)  - battle (wartime) http://mbbshelp.com
  • 4.  2. According to the character:  - incised (knife, blade)  - stab (bayonet, awl)  - chopped (axe, sabre)  - contused (blunt tools)  - crushed (blunt tools)  - lacerated (traction with sharp retractor)  - bite (animals, human)  gunshot (wound canal, primary traumatic necrosis, concussion area)  - poisoned (spiders, snakes)  combined http://mbbshelp.com
  • 5.  3. Depending on the presence of infection:  - aseptic  - infected  - purulent http://mbbshelp.com
  • 6.  4. In relation to the bodily cavities:  - penetrating  - non-penetrating  5. Depending on the presence of complications:  - non-complicated  - complicated http://mbbshelp.com
  • 7. Clinical manifestation  Pain  Bleeding  Gaping  Dysfunctions http://mbbshelp.com
  • 8. Complications of wounds  Bleeding with hemorrhagic shock  Injury of vital organs  Infection  Longterm consequences (contractures, organs insufficiency etc) http://mbbshelp.com
  • 9. Healing of the wound:  by primary intention  by secondary intention http://mbbshelp.com
  • 10. Wound healing phases:  Inflammatory phase  Proliferative phase  Remodeling phase  Epithelialization http://mbbshelp.com
  • 11. Inflammatory phase  In the inflammatory phase, bacteria and are debris are phagocytosed and removed, and factors are released that cause the migration and division of cells involved in the proliferative phase. http://mbbshelp.com
  • 12. Basic signs of inflammation  Redness (rubor)  Swelling (tumor)  Pain (dolor)  Increase in local temperature (calor)  Functions disorder http://mbbshelp.com
  • 13. Proliferative phase  The proliferative phase is characterized by angiogenesis, collagen deposition, granulation tissue formation, epithelialization, and wound contraction. http://mbbshelp.com
  • 14. Remodeling phase  In the maturation and remodeling phase, collagen is remodeled and realigned along tension lines and cells that are no longer needed are removed by apoptosis. http://mbbshelp.com
  • 15. Epithelialization  In epithelialization phase, epithelial cells migrate across the tissue to form a barrier between the wound and the environment. http://mbbshelp.com
  • 16. Factors affecting wound healing  A. General factors: – age – debilitation results in malnutrition – diabetic patients – jaundice, uremia – cytotoxic drugs and malignancy – generalized infection – Corticosteroides  B. Local factors: – poor blood supply – local infection – haematoma – faulty technique of wound closure – tension while suturing – oxygen http://mbbshelp.com
  • 17. First aid  Haemostasis (temporary or definitive)  Cleaning of surrounding skin with an antiseptic solution  Application of aseptic dressing on the wound  Transport immobilization http://mbbshelp.com
  • 18. Primary surgical wound debridement  Early (within 24 hours)  Delayed (within 24-48 hours)  Late (more than 48 hours after injury) http://mbbshelp.com
  • 19. Primary surgical wound debridement  Main purpose – prophylaxis of wound infection development http://mbbshelp.com
  • 20. Primary surgical wound debridement involves:  Excision of wound edges, bases and walls up to the intact tissues  Removing all non-vital tissues, foreign bodies, clots of blood  Repair of blood vessels, nerves, muscles  Suturing the wound http://mbbshelp.com
  • 21. Wound closure or wound suturing:  Primary suturing  Wound excision and primary suturing of skin  Wound excision and delayed primary suture  Secondary suturing http://mbbshelp.com
  • 22. Secondary surgical wound debridement:  Main purpose – surgical treatment of purulent wound http://mbbshelp.com
  • 23. Secondary surgical wound debridement involves:  Wide long incisions  Opening all pockets in wound and combined in one cavity  Excision all necrotic tissues  Insertion of drainage tubes, washing systems for permanent cleaning the wound http://mbbshelp.com
  • 24. Treatment of purulent wounds  1. In hydration phase:  - removing pus  - washing with antiseptic solutions (H2O2, furacilin, KMnO4)  - bandages with hypertonic solutions  - proteolytic enzymes  - laser, ultrasound cavitation http://mbbshelp.com
  • 25. Treatment of purulent wounds  2. In dehydration phase  - ointments with antibiotics  - ointments with substances, which stimulate reparative processes in wound (solcoseril, actovegin, metyluracil)  - physiotherapy  - secondary sutures http://mbbshelp.com
  • 26. Thank you for your attention http://mbbshelp.com