Diagnosis and Management of Malaria

1. MANAGEMENT OF
MALARIA

2. DIAGNOSIS OF MALARIA
1. Microscopy – GOLD STANDARD, Demonstration of asexual forms of
parasite in PBS
a.Thick blood film
b.Thin blood film
2. PfHRP2 dipstick or card test
3. Plasmodium LDH dipstick or card test
4. Microtube concentration methods with acridine orange staining
5. Other laboratory findings

4. LABORATORY FINDINGS
Blood –
Normocytic , Normochromic anemia
increase in ESR, CRP, and other acute phase proteins
Thrombocytopenia (~10*5/microlitre )

5. UNCOMPLICATED MALARIA
Nonspecific;
the lack of a sense of wellbeing, headache, fatigue, abdominal discomfort,
and muscle aches followed by fever .
The classic malarial paroxysms, in which fever spikes, chills, and
rigors occur at regular intervals, are relatively unusual and suggest
infection with P. vivax or P. ovale. The fever is usually irregular at
first (that of falciparum malaria may never become regular); the
temperature of nonimmune individuals and children often rises
above 40°C (104°F)

6. SEVERE FALCIPARUM MALARIA
MAJOR SIGNS-
 Unarousable coma/cerebral malaria
 Acidemia/acidosis
 Severe normochromic, normocytic anemia
 Renal failure
 Pulmonary edema/adult respiratory distress syndrome
 Hypoglycemia
 Hypotension/shock
 Bleeding/disseminated intravascular coagulation
 Convulsions
OTHERS –
Hemoglobinuria , Extreme weakness Prostration, Hyperparasitemia, Jaundice

7. TREATMENT :
1. Uncomplicated malaria
2. Severe falciparum malaria
3. Treatment of various complications

8. UNCOMPLICATED MALARIA

11. SEVERE FALCIPARUM MALARIA

13. TREATMENT OF VARIOUS
COMPLICATIONS

15. MALARIA CONTROL
• Indoor residual spraying.
• Insecticide treated bed nets.
• Electronic mosquito repellants.
• Intermittent preventive therapy.

16. THANK YOU !!!