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NUTRACEUTICALS
BY-
NITESH KUMAR
B.PHARM 7th SEM
JAIPUR COLLEGE OF PHARMACY
JAIPUR, RAJASTHAN
NUTRACEUTICALS
 The term was coined in 1989 by Dr. Stephen De
Felice ( Chairman of the Foundation for innovation
in Medicine ).
DEFINITION
 A nutraceuticals is a substance that is food or a part
of food treatment of diseases.
 Nutraceuticals can be defined as a food or a part of
food or a nutrient, which in addition to its nutrient
values provides health benefits including promotion
of health and prevention of diseases.
OBJECTIVES
 To increase Nutritional factor of food.
 Activates immunity.
 Increase feed consumption
 Induce maturation
 Anti- microbial capability
 No negative environment impact or hazardous
problems.
Nutraceuticals also known as
 Phytoceuticals
 Phytochemicals
 Phytonutrients
 Phytofoods
 Functional foods
GLOBAL MARKET OVERVIEW AND GROWTH OF
NUTRACEUTICALS SEGMENT
 The market is predicted to record a revenue of USD
671.30 billion by 2024.
 The demand for nutraceuticals is expected to rise in
developing countries which have high prevalence of
non-communicable diseases.
 Nutraceuticals are also gaining global importance
and have become a part of daily diet due to
increased risk of diseases due to improper lifestyle..
 Nutraceuticals have become an opportunity for
economic growth of many developing countries
which have a rich source of medicinal herbs and
traditional knowledge of such plants, especially
India, china and south American countries.
 The gradually increasing healthcare expenses are
also stimulating the demand for nutraceuticals.
 Nutraceuticals strengthens the body defence
mechanisms and improves the body’s immunity
towards the disease.
SCOPE OF NUTRACEUTICALS
 Nutraceuticals are expected to deliver promising
outcomes in the prevention and occurrence of
various diseases due to improper lifestyle and food
habits.
 Various constituents of plants like catechins,
cartenoids, lycopene, polyphenols, PUFA. etc..
Have been very effective in the prevention and
occurrence of various diseases like CVS, arthritis,
cancer, GIT disorder etc.
CLASSIFICATION
1. Natural sources
2. Pharmacological condition
3. Chemical constituents
Classification : Based on their sources
1. Plant :- Tomato, garlic, Momordica
2. Animal :- Shark, liver oil, cod liver oil
3. Minerals :- calcium, Magnesium, Phosphorus
4. Microorganism :- Bifidobacterium, Lactobacilli.
Classification based on their chemical groupings
1. Inorganic mineral supplements :- Minerals like
calcium, magnesium, manganese, boron,
copper, zinc.
2. Probiotics :- E. coli, Bacillus species, species of
lactobacillus.
3. Prebiotics :- Digestive enzymes.
4. Dietary fibers :- Structural carbohydrates of plants.
5. Antioxidants :- Natural antioxidants.
6. Phytochemicals :- fatty acids, lipids.
7. Digestive enzymes :- Enzymes.
ROLE OF NUTRACEUTICALS IN DISEASES
1. DIABETES
 Lipolic acid - Universal anti-oxidant for treatment of
Neuropathy.
 Dietary fibres – Posses reduction in weight by
glucose and lipid control.
2. CVS SYSTEM
 Nutraceuticals in the form of antioxidant, dietary
fibers, vitamins, minerals are used with physical
exercise for prevention and treatment of CVS
disorder.
 Polyphenol present in grape wine reduce arterial
disease.
 Flavonoids are widely distributed in onion, black
grapes, red wine, apple, cherries.
 Flavonoids protect vascular and capillaries that
supply oxygen and nutrients.
3. CANCER
 Nutraceuticals have ability to control and regulate
the DNA damaging factor in cancer cells.
 It has proven to be potential to interfere even at
late stage cancer and alter the metastatic spread of
cancer by increasing the phytochemicals.
By utilizing daily diet of nutraceuticals specific sides to
entire gene combination found in particular form of
cancer.
4. IRRITABLE BOWEL SYNDROME
 Dietary supplements such as fish oil, curcumin oil,
aloe Vera treat bowel syndrome.
 Curcumin and green tea supplementation cause
reduction in IBD.
5. GIT
 The GIT disorder refers to any condition or
disease within the GI tract. This also includes liver,
Pancreas, Gall bladder.
IMPORTANT HERB AS HEALTH FOOD
ALFAALFA
 Family – fabaceae / leguminosae
 Species – medicago sativa
 Active constituents – carotenoids, triterpenoids,
saponin, isoflavonoid
 Part used – Herb
 Herbal uses – Arthritis, high cholesterol, diabetic,
peptic ulcer.
CHICORY
 Synonym – kaasani
 Biological source – Dried leaves and roots of
chichorium intybus.
 Family – Compositae
 Active constituents – Flavonoids, tannins,
triterpenoids, umbeliferon,
scopoletin.
 Herbal uses – Jaundice, liver problems, Diabetes,
intestinal worms.
GINGER
 Biological source – Zingibar officinalis
 Family – Zingiberaceae
 Active constituents – Gingerol, shagol,
Zingiberin,
Starch, Zingeberol
 Herbal uses – Boost digestion, control Nausea,
Reduce arthritis, Increase blood
flow,
FENUGREEK
 Synonym – Medhika, methi
 B.S. – Dried ripe seeds of Trigonella foenum
 Family – Leguminoseae
 Active constituents – Fenugreekine, trigonellin,
Diosgenin.
 Herbal uses – Diabetes, Hyperlipidemia,
Hypercholesterol, ulcer, upper
respiratory tract infection, Arthritis.
GARLIC
 Synonym – Lasun
 B.S. – Dried bulbs of Allium sativum
 Family – Lilliaceae
 Active constituents – Allicin, Allyl propyl
disulphide, selenium, scordinins.
 Active constituents – Allicin, Allyl propyl
disulphide, selenium, scordinins.
 Herbal uses – Hypertension, Diabetes,
Hypercholesterol, Hyperlipidaemia,
flatulence, spasm.
HONEY
 Synonym – Madhu
 B.S. – Sugar secretion deposited in honey comb by
bees
Apis mellifera, Apis dorsata
 Family – Apidae
 Active constituents – Glucose, Fructose, Dextrin,
Maltose, Formic acid, Acetic
acid.
AMLA
 Synonym – Amalaki, Indian gooseberry
 B.S. – Dried ripe fruits of phyllanthus embilica
 Family – Euphorbiaceae
 Active constituents – Gallic acid, Ellagic acid,
Vit. C,
Amino acid, Phyllembin
 Herbal use – Powerful antioxidant, accelerates
the cell
regeneration, Building the body’s
immune
system.
GINSENG
 Synonym – ninjin
 B.S. – Dried roots of Panax ginseng
 Active constituents – Oleanic acid, panaxidol,
panaxotriol,
Dammarol
 Herbal uses – Stress, Fatigue, Erectile
dysfunction,
Hyperglycemia, Aging, CVS,
Menopausal
symptoms.
ASHWAGANDHA
 Synonym – Withania
 B.S. – Dried roots of Withania somnifera
 Family – Solanaceae
 Active constituents – Tricontane,
Dihydroxystigmasterol,
Withamine, Somnine, Amino
acid,
Withanolides, withaferine A
SPIRULINA
 B.S. – Blue green algae, Spirulina platensis &
Spirulina
maxima
 Family – Oscillatoriaceae
 Active constituents – Beta carotene, Protenous
nitrogen, lipid, vitamin F, Fatty
acid, Phycobiliprotein,
glycogen,
rhamnose.
 Herbal uses – Immunostimulatory, Hypolipidemic
antiviral, Anti-inflammatory and anti-
cancer effects.
TYPES OF NUTRACEUTICALS PRODUCTS
AVAILABLE
IN MARKET
1. FUNCTIONAL FOOD -- Cereals, Bakery,
Confectionary, Dairy, Snacks, Functional fat, oil,
Baby food.
2. FUNCTIONAL BEVERAGES – Energy drink,
Sports drink, Fortified juice, Dairy beverages,
Tea, coffee.
3. DIETARY SUPPLEMENTS – Vitamins, Minerals,
Botanicals, Enzymes, Fatty acid, Proteins,
Probiotics, Prebiotics.

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Nutraceuticals by nitesh

  • 1. NUTRACEUTICALS BY- NITESH KUMAR B.PHARM 7th SEM JAIPUR COLLEGE OF PHARMACY JAIPUR, RAJASTHAN
  • 2. NUTRACEUTICALS  The term was coined in 1989 by Dr. Stephen De Felice ( Chairman of the Foundation for innovation in Medicine ). DEFINITION  A nutraceuticals is a substance that is food or a part of food treatment of diseases.  Nutraceuticals can be defined as a food or a part of food or a nutrient, which in addition to its nutrient values provides health benefits including promotion of health and prevention of diseases.
  • 3. OBJECTIVES  To increase Nutritional factor of food.  Activates immunity.  Increase feed consumption  Induce maturation  Anti- microbial capability  No negative environment impact or hazardous problems. Nutraceuticals also known as  Phytoceuticals  Phytochemicals  Phytonutrients  Phytofoods  Functional foods
  • 4. GLOBAL MARKET OVERVIEW AND GROWTH OF NUTRACEUTICALS SEGMENT  The market is predicted to record a revenue of USD 671.30 billion by 2024.  The demand for nutraceuticals is expected to rise in developing countries which have high prevalence of non-communicable diseases.  Nutraceuticals are also gaining global importance and have become a part of daily diet due to increased risk of diseases due to improper lifestyle..  Nutraceuticals have become an opportunity for economic growth of many developing countries which have a rich source of medicinal herbs and traditional knowledge of such plants, especially India, china and south American countries.
  • 5.  The gradually increasing healthcare expenses are also stimulating the demand for nutraceuticals.  Nutraceuticals strengthens the body defence mechanisms and improves the body’s immunity towards the disease. SCOPE OF NUTRACEUTICALS  Nutraceuticals are expected to deliver promising outcomes in the prevention and occurrence of various diseases due to improper lifestyle and food habits.  Various constituents of plants like catechins, cartenoids, lycopene, polyphenols, PUFA. etc.. Have been very effective in the prevention and occurrence of various diseases like CVS, arthritis, cancer, GIT disorder etc.
  • 6. CLASSIFICATION 1. Natural sources 2. Pharmacological condition 3. Chemical constituents Classification : Based on their sources 1. Plant :- Tomato, garlic, Momordica 2. Animal :- Shark, liver oil, cod liver oil 3. Minerals :- calcium, Magnesium, Phosphorus 4. Microorganism :- Bifidobacterium, Lactobacilli. Classification based on their chemical groupings 1. Inorganic mineral supplements :- Minerals like calcium, magnesium, manganese, boron, copper, zinc.
  • 7. 2. Probiotics :- E. coli, Bacillus species, species of lactobacillus. 3. Prebiotics :- Digestive enzymes. 4. Dietary fibers :- Structural carbohydrates of plants. 5. Antioxidants :- Natural antioxidants. 6. Phytochemicals :- fatty acids, lipids. 7. Digestive enzymes :- Enzymes. ROLE OF NUTRACEUTICALS IN DISEASES 1. DIABETES  Lipolic acid - Universal anti-oxidant for treatment of Neuropathy.  Dietary fibres – Posses reduction in weight by glucose and lipid control.
  • 8. 2. CVS SYSTEM  Nutraceuticals in the form of antioxidant, dietary fibers, vitamins, minerals are used with physical exercise for prevention and treatment of CVS disorder.  Polyphenol present in grape wine reduce arterial disease.  Flavonoids are widely distributed in onion, black grapes, red wine, apple, cherries.  Flavonoids protect vascular and capillaries that supply oxygen and nutrients. 3. CANCER  Nutraceuticals have ability to control and regulate the DNA damaging factor in cancer cells.  It has proven to be potential to interfere even at late stage cancer and alter the metastatic spread of cancer by increasing the phytochemicals.
  • 9. By utilizing daily diet of nutraceuticals specific sides to entire gene combination found in particular form of cancer. 4. IRRITABLE BOWEL SYNDROME  Dietary supplements such as fish oil, curcumin oil, aloe Vera treat bowel syndrome.  Curcumin and green tea supplementation cause reduction in IBD. 5. GIT  The GIT disorder refers to any condition or disease within the GI tract. This also includes liver, Pancreas, Gall bladder.
  • 10. IMPORTANT HERB AS HEALTH FOOD ALFAALFA  Family – fabaceae / leguminosae  Species – medicago sativa  Active constituents – carotenoids, triterpenoids, saponin, isoflavonoid  Part used – Herb  Herbal uses – Arthritis, high cholesterol, diabetic, peptic ulcer. CHICORY  Synonym – kaasani  Biological source – Dried leaves and roots of chichorium intybus.
  • 11.  Family – Compositae  Active constituents – Flavonoids, tannins, triterpenoids, umbeliferon, scopoletin.  Herbal uses – Jaundice, liver problems, Diabetes, intestinal worms. GINGER  Biological source – Zingibar officinalis  Family – Zingiberaceae  Active constituents – Gingerol, shagol, Zingiberin, Starch, Zingeberol  Herbal uses – Boost digestion, control Nausea, Reduce arthritis, Increase blood flow,
  • 12. FENUGREEK  Synonym – Medhika, methi  B.S. – Dried ripe seeds of Trigonella foenum  Family – Leguminoseae  Active constituents – Fenugreekine, trigonellin, Diosgenin.  Herbal uses – Diabetes, Hyperlipidemia, Hypercholesterol, ulcer, upper respiratory tract infection, Arthritis. GARLIC  Synonym – Lasun  B.S. – Dried bulbs of Allium sativum  Family – Lilliaceae  Active constituents – Allicin, Allyl propyl disulphide, selenium, scordinins.
  • 13.  Active constituents – Allicin, Allyl propyl disulphide, selenium, scordinins.  Herbal uses – Hypertension, Diabetes, Hypercholesterol, Hyperlipidaemia, flatulence, spasm. HONEY  Synonym – Madhu  B.S. – Sugar secretion deposited in honey comb by bees Apis mellifera, Apis dorsata  Family – Apidae  Active constituents – Glucose, Fructose, Dextrin, Maltose, Formic acid, Acetic acid.
  • 14. AMLA  Synonym – Amalaki, Indian gooseberry  B.S. – Dried ripe fruits of phyllanthus embilica  Family – Euphorbiaceae  Active constituents – Gallic acid, Ellagic acid, Vit. C, Amino acid, Phyllembin  Herbal use – Powerful antioxidant, accelerates the cell regeneration, Building the body’s immune system. GINSENG  Synonym – ninjin  B.S. – Dried roots of Panax ginseng
  • 15.  Active constituents – Oleanic acid, panaxidol, panaxotriol, Dammarol  Herbal uses – Stress, Fatigue, Erectile dysfunction, Hyperglycemia, Aging, CVS, Menopausal symptoms. ASHWAGANDHA  Synonym – Withania  B.S. – Dried roots of Withania somnifera  Family – Solanaceae  Active constituents – Tricontane, Dihydroxystigmasterol, Withamine, Somnine, Amino acid, Withanolides, withaferine A
  • 16. SPIRULINA  B.S. – Blue green algae, Spirulina platensis & Spirulina maxima  Family – Oscillatoriaceae  Active constituents – Beta carotene, Protenous nitrogen, lipid, vitamin F, Fatty acid, Phycobiliprotein, glycogen, rhamnose.  Herbal uses – Immunostimulatory, Hypolipidemic antiviral, Anti-inflammatory and anti- cancer effects.
  • 17. TYPES OF NUTRACEUTICALS PRODUCTS AVAILABLE IN MARKET 1. FUNCTIONAL FOOD -- Cereals, Bakery, Confectionary, Dairy, Snacks, Functional fat, oil, Baby food. 2. FUNCTIONAL BEVERAGES – Energy drink, Sports drink, Fortified juice, Dairy beverages, Tea, coffee. 3. DIETARY SUPPLEMENTS – Vitamins, Minerals, Botanicals, Enzymes, Fatty acid, Proteins, Probiotics, Prebiotics.