Successfully reported this slideshow.
We use your LinkedIn profile and activity data to personalize ads and to show you more relevant ads. You can change your ad preferences anytime.

Related Books

Free with a 30 day trial from Scribd

See all

N A N O M E D I C I N E 2 K7

  1. 2. NANO MEDICINE : PROMISE OF THE FUTURE IN DISEASE MANAGEMENT Co-ordinator : Mrs. Pavani , M.pharm Author : Srinivas Dinakar.N
  2. 3. <ul><li>Introduction </li></ul><ul><li>Nano medicine is the medical use of molecular sized particles to deliver drugs, of heat, light or other substances to specific cells in the human body </li></ul><ul><li>The applications of nano medicine in the fields of cancer therapy, disease diagnosing, drug delivery etc makes up just the tip of the ice berg of what nano medicine is going to offer us </li></ul>
  3. 4. <ul><li>Scopes in disease management </li></ul><ul><li>Every thing is made so simple </li></ul><ul><li>through nano medicine </li></ul><ul><li>First cancer cells that may have </li></ul><ul><li>transformed in to tumor poise to </li></ul><ul><li>kill us can be destroyed </li></ul><ul><li>Broken parts if cells can be removed or </li></ul><ul><li>replaced with miniature biological machines </li></ul><ul><li>Life saving drugs can be delivered with </li></ul><ul><li>assistance of miniature nano pumps </li></ul>
  4. 5. <ul><li>Applications of nano medicine </li></ul><ul><li>Nanostructure implants in drug </li></ul><ul><li>delivery ,nanostructure scaffolds </li></ul><ul><li>for tissue engineering </li></ul><ul><li>Nanostructure for cell expansion </li></ul><ul><li>Disease diagnosing by targeted </li></ul><ul><li>nano particles </li></ul><ul><li>Nanoparticle for efficient ,highly </li></ul><ul><li>sensitive, and high throughput bio </li></ul><ul><li>assays </li></ul><ul><li>Improve efficacy, reduction in dose </li></ul><ul><li>and side effects </li></ul>
  5. 6. <ul><li>Medical nano robots </li></ul><ul><li>Nano robots can patrol our body and </li></ul><ul><li>fight any foreign body that is likely </li></ul><ul><li>to infect </li></ul><ul><li>Medical nano devices injected which </li></ul><ul><li>would go to work in specific organ </li></ul><ul><li>or tissue mass </li></ul><ul><li>These are for parentral,oral,ocular, </li></ul><ul><li>transdermal applications as well as </li></ul><ul><li>used in cosmetics and hair care technologies </li></ul><ul><li>Typical size of blood born nano robot </li></ul><ul><li>will be 0.5 - 3µ </li></ul><ul><li>carbon would be primary element used to build </li></ul><ul><li>They are of greater importance in easy and </li></ul><ul><li>accurate correction of genetic defects </li></ul>
  6. 7. <ul><li>Nano particles </li></ul><ul><li>Nano spheres and nano capsules, </li></ul><ul><li>that can be either amorphous </li></ul><ul><li>or crystalline </li></ul><ul><li>They are specifically designed to </li></ul><ul><li>absorb or encapsulate a drug, </li></ul><ul><li>thereby protecting it against </li></ul><ul><li>chemical and enzymatic degradation </li></ul><ul><li>For targeting particular organs/tissues </li></ul><ul><li>and also as carriers of DNA in gene therapy, </li></ul><ul><li>to deliver proteins, peptides and genes by oral route. </li></ul>
  7. 8. <ul><li>Nano particle delivery systems </li></ul><ul><li>It focuses in the production </li></ul><ul><li>of nanoscale particles or </li></ul><ul><li>molecules to enhance the </li></ul><ul><li>bioavailability of a drug </li></ul><ul><li>It also focuses on maximizing </li></ul><ul><li>bioavailability and for </li></ul><ul><li>prolonged period of time </li></ul><ul><li>The advantage is that cells can take up the nano particles because of their incredibly small size ,avoidance of macrophage clearence,long resistant times </li></ul>
  8. 9. <ul><li>Applications in cancer therapy </li></ul><ul><li>Novel nano medical anticancer therapies </li></ul><ul><li>with much lesser pain and side effects </li></ul><ul><li>are becoming ultimate solutions </li></ul><ul><li>Small size empowers them properties </li></ul><ul><li>that can be very useful in oncology , </li></ul><ul><li>particularly in imaging </li></ul><ul><li>This implies that use of fluorescent quantum dots </li></ul><ul><li>could produce a higher contrast image </li></ul><ul><li>Specialty is the higher surface area to volume ratio </li></ul><ul><li>empowers a large number of functional groups to </li></ul><ul><li>attach a single nano particle which bind to targeted </li></ul><ul><li>tumor cells </li></ul>
  9. 10. <ul><li>Novel cancer treatment methods </li></ul><ul><li>Kanizus radio frequency therapy is </li></ul><ul><li>promising cancer treatment method </li></ul><ul><li>The method has potential to replace </li></ul><ul><li>radiation and chemotherapy used today </li></ul><ul><li>Nanoparticles attach to cancer cells and </li></ul><ul><li>cooks the tumors literally with help of </li></ul><ul><li>radio frequency waves that heat only </li></ul><ul><li>the nanoparticle attached tumor cells </li></ul><ul><li>Destruction of cancer tumors in mice with the help of 120nm diameter nanoshells coated with gold was done </li></ul>
  10. 11. <ul><li>Nanoshells can be targeted to bond to </li></ul><ul><li>cancer tumor cells by conjugating </li></ul><ul><li>antibodies or peptides to the surface </li></ul><ul><li>of nanoshell </li></ul><ul><li>An anticancer nanocrystal was created </li></ul><ul><li>which has an outer shell that encloses </li></ul><ul><li>yolk consisting two metals gold and </li></ul><ul><li>platinum responsible for activity of </li></ul><ul><li>widely acclaimed anticancer drug </li></ul><ul><li>Cisplatin was used </li></ul><ul><li>Nanostructures can be coated with </li></ul><ul><li>antibodies that can specifically target </li></ul><ul><li>cancerous tissues </li></ul>
  11. 12. <ul><li>Nanovaccines </li></ul><ul><li>Nanovaccines are created which in </li></ul><ul><li>reality specialized nanoemulsions </li></ul><ul><li>made up of tiny Soya bean oil droplets </li></ul><ul><li>suspended in water and studded with </li></ul><ul><li>bits of pathogenic organisms </li></ul><ul><li>These can be ingested by swabbing in to the nose </li></ul><ul><li>Since they are swabbed they produce </li></ul><ul><li>immunity not only in the blood stream </li></ul><ul><li>but also in mucous lining making them </li></ul><ul><li>relevant for varied diseases </li></ul><ul><li>They have potential to change small pox </li></ul><ul><li>vaccination process </li></ul>
  12. 13. <ul><li>Nanotoxicology </li></ul><ul><li>Silver nanoparticles which are bacteriostatic , </li></ul><ul><li>may then destroy beneficial bacteria which </li></ul><ul><li>are important for breaking down organic matter </li></ul><ul><li>in waste treatment plants or farms </li></ul><ul><li>Nature nanomedicine suggests some forms of </li></ul><ul><li>carbon nanotubes could be as harmful as asbestos </li></ul><ul><li>if inhaled in sufficient quantities </li></ul><ul><li>Future in disease management </li></ul><ul><li>The approaches to nanomedicine range from the medical use of nanomaterials to nanoelectronic biosensors and even possible and even future applications of molecular nanotechnology </li></ul>
  13. 14. <ul><li>Conclusion </li></ul><ul><li>Nanomedicine is been put to the maximum use and benefits reach every sections of the society thereby alleviating the pains of millions of people around the world. </li></ul>