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By: Olla BaEissa
Types of immunoglobulins
Immunogloblin
heavy
chain
structure Function or roles note
IgG Gamma  Monomer o...
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Types of immunoglobulins

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Biochemestry _ BDS level 4 _ Types of immunoglobulins

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Types of immunoglobulins

  1. 1. By: Olla BaEissa Types of immunoglobulins Immunogloblin heavy chain structure Function or roles note IgG Gamma  Monomer only 1- have the ability to traverse the blood vessels to tissues 2- pass through the placenta to the fetus 3- important in the secondary response They are the most abundant of the circulating antibodies IgA Alpha  - monomer in serum (blood) - dimer in secretions as sweat, tears and saliva and in mucosal fluids - protect the walls of bronchi and small intestine. - high concentration in breast milk - help in transferring immunity to the new born infants IgM Mu  pentamer They are produced in the primary immune response 2- They are restricted to the blood stream due to high mass 3- important in the primary response Its subunits are held together by a glycoprotein called j-chain (joining chain). IgD Delta  monomer 1- present on the surface of B cells where they function as receptors for antigens 2-their function in serum is not yet defined present on the surface of B cells IgE Epsilon  monomer 1- important in protection against parasites 2- They are involved mainly in the development of allergic responses 3- the release of histamine, 4- which produces contraction of smooth muscles and 5 - stimulates secretion of mucus.

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