Myself Omkar Tipugade , M pharm , Shree Santkrupa College of Pharmacy , Ghogaon , Karad ( Maharashtra).
I upload the presentation on sun protection & type of Skin and sun screen agent depend on skin type , and also brief information about the cosmetic & cosmeceutical product.
1. DESIGN OF COSMECEUTICAL
PRODUCT : SUN PROTECTION
Mr. Omkar Tipugade
M–Pharm, Sem II ( Pharmaceutics)
Shree Santkrupa College Of Pharmacy, Ghogaon.
2. AGENDA:
Introduction to cosmeceutical
Sun protection :
I. Introduction
II. Sun screen
III. Sunscreen classification
IV. Ideal sunscreen agent
V. Skin type & choice of sunscreen
VI. SPF value
3. INTRODUCTION TO COSMECEUTICAL
Cosmeceutical is an ingredient with medicinal properties, which
manifests beneficial topical action and provide protection against
degenerative skin conditions.
Are cosmetic product with biologically active ingredient purpoting to have
medical or drug like benefits.
The FD & C act does not recognize any such category as “
cosmeceutical “ A product can be drug , a cosmetic or a combination of
both , but the term “ cosmeceutial “has no meaning under the law.
Are product that have both cosmetic and therapeutics effect and are
intended to have beneficial effect on skin health and beauty.
Cosmetical are available “ over the counter “ & are generally used as a
part of a regular skin care regime to help improve skin tone and texture ,
pigmentation and fine lines
4. SUN PROTECTION
I. Introduction
Radiation of wavelength 2000-2500A° : penetrate the blood
veseels reaching the papillary layer.
3200 -3900 A° : reach dermal
2800-3200 A° : are both erythemogenic ( capble of producing
redness ) & pigmentogenic.
More than 3900 A° : heating action.
Intensity of erythema depend on absorption of ultra violet
radiation.
Three type of skin tannings : 1. immediate tanning
2. delayed tanning
3. true tanning
5. sun burns are the result of damage or destruction of cell in the prickle cell
layer of epidermis
Histamine like substance released by the damaged or destructed cell
causes dilation of blood vessel & erythma . These substance also cause
swelling of the skin and stimulate basal cell to proliferate.
Sun burn classified into four degree:
Degree 1: minimum erythema
degree 2 : vivid erythema
degree 3 : painful burn
degree 4 : blistering burn
6. II .Sun screen:
Purpose of suntan preparation is to assist the skin in tanning without
painful effect & the purpose of anti-burn preparation is to minimize the
harmful effect of the sunburn.
A number of organic compound have been screened for sunscreening
properties:
a. Azole
b. P-aminobenzoic acid & its derivatives.
c. Cinnamic acid derivatives
d. Coumarin derivatives
e. Quinine salt
f. Dibenzalactone & benzal actophenone
g. Hydrocarbon
h. Hydroquinone
i. Uric acid & violuric acid
j. anthraniltes
7. III. Sunscreen classification :
A) Physical
- Opaque formulation containing :
*titanium dioxide
*talc , kaolin
*zinc oxide
*ferric chloride
*icthyol , red petrolatum
- Mechanism : scatters of reflects UV radiation due to large
particles size .
8. B) Chemical
- formulation containing one or more :
*PABA ,PABA ester
* benzophenones
* cinnamates
* salicylates
* digalloyl trioleate
* anthranilates
- Mechanism : absorbs UV radiation
9. IV. Ideal sunscreen agent
It should absorb erythonogenic radiation in the range of 290-320nm
without its break down.
Its should allow full transmission of radiation in the range of 300-400nm
for tanning effect.
Should be resistant to water & perspiration & should also be non-volatile.
Should have suitable solubility characteristics.
Odourless or should have only mild characteristics.
Non-toxic, non -irritant and non-sensitizing.
Should be capable of retaining its sunscreening property for several
hours.
Should be stable under condition of use.
Should not stain.
10. V.Skin type & choice of sunscreen:
US FDA classification system for sunscreen product comprises of five
product category designation (PCD) to meet requirement of consumers
with different type of skin.
Depending upon skin type & tanning history they are classified into six
group :
a. Always burns easily & never tan (i.e.sensitive)
b. always burns & tan minimally
c. burns moderately & tan gradually to a shade of light brown (i.e.normal)
d. burn minimally & always tans well (i.e.normal)
e. barely burn & tans profusely skin become dark brown (i.e.Insensitive)
f. never burn & skin become deeply pigmented.
11. VI .SPF value
The SPF has been defined as ratio between the UV exposure required to
produce a minimally perceptible erythema on protected skin & the
exposure that will produce the erythema on unprotected skin
The formal defination of SPF by the OTC Panel of the US FDA was
SPF value : MED (PS) / MED (US)
PS : minimum erythemal dose for protected skin after the application of
2mg/cm² of the final formulation of the sunscreen product .
US : minimum erythemal dose for unprotected skin i.e.skin to which no
sunscreen product has been applied .
the larger the SPF , the greater the sun protection
12. For skin type mentioned above , sunscreening product with the following
SPF are recommended .
Skin type SPF
I 8 or more
II 6-7
III 4-5
IV 2-3
V 2
VI non-indicated