Introduction Types of febrile seizures Causes Of Febrile Seizures Treatment Aim & Objectives

1. LITERATURE REVIEW OF FEBRILE
SEIZURES
Submitted By:
Pankaj Kumar Maurya
Roll no: 1438689
DEPARTMENT OF PHARMACY PRACTICE
ISF COLLEGE OF PHARMACY, MOGA
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Supervisor:
Dr. Mandeep kaur
Assistant Professor

2. Introduction
Febrile seizures(FS) are defined as a
convulsions that can happen during a fever
(febrile means “feverish”).
They affect kids 3 month to 6 year old.
Febrile most common in babies of 12-18
months old.
The seizures usually last for a few minutes
and a fever above 100.4⁰F (38°C )
Types of febrile seizures
Simple febrile seizures.
Complex febrile seizers.
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3. Introduction
Simple febrile seizures are usually over in a few
minutes. But in rare cases they can last up to 15
minutes.
During this type of seizure, a child’s whole body
convulse, shake and twitch eyes may role and she or
he moan or become unconscious.
Children sometime vomit or urinate on themselves
during the convulsions.
Complex febrile seizers can last more than 15
minutes or happen or then once in 24 hours.
They may also involve movement or twitching of just
one part of the body.
Febrile stop on their own
While the fever may continue for sometime.
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4. Causes Of Febrile Seizures
Infection :-Usually the fever that triggers are caused
by a viral infection and less commonly by a bacterial
infection, such as flu and roseola.
Post –Immunization Seizures :-The risk of febrile
seizure may increased due to some childhood
immunization,such as Diphtheria,Tetanus and
Pertussis vaccinations.
Family History :-Some children inherit a family’s
tendency to have seizures with a fever.
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5. Treatment
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Patients with active seizures should be treated
with airway management.
Anti-pyretic drugs (Acetaminophen,
Ibuprofen) are used in febrile seizure by given
oral or rectal route (when fever is started).
Anti-convulsant agents (Diazepam,
Lorazepam) after these drugs record child heart
rate, blood pressure and breathing.
Sometimes by sponging with room
temperature water (not cold).

6. Aim & Objectives
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Review the risk factor of febrile
seizures.
To know about the method to Improve
Patient care.
To Determine the Sign and Symptoms

7. Literature review
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S.NO Author Article YEAR
1 Nooruddin R Tejani Febrile Seizures 2017
2 Syndi Seinfeld and John
M. Pellock
Recent Research on
Febrile Seizures
2014
3 Tonia Jones and Steven j.
Jacobsen
Childhood Febrile
Seizures
2007
4 Harvey, Eric, Adam and
Thomas
Treatment of Pediatric
Neurological Disorders
2005
5 C Waruiru, R Appleton Febrile Seizures 2004
6 Anne, T Berg,Shlomo
Shinnar Allen Hauser
A Prospective Study Of
Recurrent Febrile Seizures
1992

8. Literature review
8
S.NO Author Article YEAR
1 Janet L. Patterson Febrile Seizures 2013
2 Siba Prosad Paul Management of Febrile
Convulsion In Children
2015
3 P.D Singhi, K. jayshree Febrile Seizures An
Update
1995
4 Jithangi Wanigasinghe Management Of Simple
Febrile Seizures
2017
5 Abdulafeez M.Khair and
Dala Elmagrabi
Febrile Seizures And
Febrile seizures
Syndromes: An Updated
Overview Of Old And
Current Knowledge
2015

9. To find out relevant articles
Review of articles
Compilation of information from different
articles
Compilation of thesis
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Plan Of Work

10. Febrile seizures are the most common type of
childhood seizures. The peak age of onset febrile
seizures are 18 months. With temperature more than
38°C.
Signs and symptoms include , loss of consciousness,
Jerking of arm and legs, difficulty breathing, foaming at
the month,
Management involve symptom control and treating the
cause of the fever.
Febrile seizures do not cause neurological damage.
Complex FS particularly if prolonged and an abnormal
neurological status are recognised risk factor for the
development of later epilepsy.
It is important to realize some special febrile seizures
syndromes ,which can have some long-term neurological
abnormalities. 10
Conclusion

11. The risk of febrile seizures increased after certain
combination of vaccines. Like, pneumococcal conjugate
vaccine (PCV), trivalent inactivated influenza vaccine and
diphtheria-tetanus-acellular-pertussis (DTaP). But the
absolute risk of febrile seizures after these combination is
less.
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Conclusion

12. Syndi Seinfeld ,John M. Pellock; Recent research on febrile
Seizures; J Neurol Neurophysiol 2014; 4(165):1-13.
Tonia Jones, Steven J. Jacobsen; Childhood febrile seizure;. Int. J.
Med. Sci.; 2007; 4:111-112.
Nooruddin R Tejani; Febrile Seizures; medscape; 2017.
Harvey, Eric, Adam,Thomas; Treatment of Pediatric Neurological
Disorders; Taylor & Francis Group; 2005; 73-79.
C Waruiru, R Appleton; Febrile Seizures; Arch Dis Child 2004;
89:751–756; doi: 10.1136/adc.2003.028449
Anne, T Berg,Shlomo Shinnar, Allen Hauser et al; A Prospective
Study Of Recurrent Febrile Seizure; .The New England Journal of
Medicine ; 1992; 327; 1122-1127.
Patterson Janet.L. , A. Stephanie, Carapetian, et al;. Febrile
Seizures;. Pediatric Annals. 2013; 45(12):258-263.
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References

13. M.K. Abdulhafeez and E. Dalal. Febrile Seizures and Febrile
Seizure Syndromes: An Updated Overview of Old and Current
Knowledge,” Neurology Research International, vol.2015, no.7,
pp.7, 2015.
S.P. Paul, .Management Of Febrile Convulsion In
Children.Journals.rcni, vol.23, number 2, pp. 1,2015.
Singhi P.D, Jayshree K. Febrile seizures: An update. Indian
Pediatrics. 1995; 32:565-572.
Duffy Jonathan, Weintraub Eric, Simon, et al. Febrile seizures risk
after vaccination in children 6 to 23 months.
Pediatrics.2016;138(1):e20160320.
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References

14. Thank you !!!....
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