Addison’s Disease

Addison’s Disease Ali Chakera

Focus for Discussion ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

Start with a case ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

VE, 26F ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

Addison’s Disease ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

Clinical Suspicion ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],Laboratory results Signs Symptoms

Testing for Addison’s disease ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

Causes of Addison’s disease ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

Causes of Addison’s disease ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],Drugs ,[object Object],[object Object],Infiltration Haemorrhage / infarction Bilateral adrenalectomy ,[object Object],[object Object],[object Object],Infective ,[object Object],[object Object],[object Object]

Optimum treatment? ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

Monitoring? ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

Clinical monitoring? ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

On the Horizon ,[object Object],[object Object],[object Object]

Treatment in Surgery ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

Is there a good screening test?

Is a baseline cortisol of value? ,[object Object],[object Object],[object Object],[object Object],[object Object]

Our results over the past year ,[object Object],[object Object],[object Object]

Synacthen Tests for Ali Chakera.xls 18 202 21.9 NNV 88.9 Specificity 73 16 57 Negative 98.6 PPV 71.8 Sensitivity 147 2 145 Positive Test > 250 No Yes Normal Adrenals 18 202 16.7 NNV 100.0 Specificity 108 18 90 Negative 100.0 PPV 55.4 Sensitivity 112 0 112 Positive Test > 300 No Yes Normal Adrenals

Our results for the past 3 years ,[object Object],[object Object],[object Object]

3 years of synacthen results.xls 57 591 15.0 NNV 98.2 Specificity 374 56 318 Negative 99.6 PPV 46.2 Sensitivity 274 1 273 Positive Test > 350 No Yes Normal Adrenals 58 590 12.8 NNV 98.3 Specificity 445 57 388 Negative 99.5 PPV 34.2 Sensitivity 203 1 202 Positive Test > 400 No Yes Normal Adrenals

Conclusions ,[object Object],[object Object],[object Object]

Addison’s Disease

Recommended

Recommended

More Related Content

What's hot

What's hot (20)

Viewers also liked

Viewers also liked (8)

Similar to Addison’s Disease

Similar to Addison’s Disease (20)

More from PeninsulaEndocrine

More from PeninsulaEndocrine (20)

Recently uploaded

Recently uploaded (20)

Addison’s Disease