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Diabetes Insipidus Dr Thomas Fox  Endocrine SpR RCH
[object Object],[object Object],[object Object]
Outline ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Anti-diuretic hormone (Arginine Vasopressin ) ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
                                                                                          
Water homeostasis ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Role of ADH ,[object Object],[object Object],[object Object],[object Object],[object Object]
H20 H20 Collecting Duct Principal cell ADH DNA AQP 2 Synthesis Transport AQP 2 ADH affect on kidney V2 R
ADH production ,[object Object],[object Object],[object Object],[object Object]
ADH Production in response to volume and osmolality changes
ADH Production ,[object Object],[object Object],[object Object],[object Object]
Case 1 ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Case cont ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
2 years later ,[object Object],[object Object],[object Object],[object Object],[object Object]
On admission ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
[object Object],[object Object],[object Object],[object Object]
Treatment - medical ,[object Object],[object Object],[object Object],[object Object],[object Object]
Treatment – surgical ,[object Object],[object Object],[object Object]
Case 2 ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Further investigations ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Ophthalmology review ,[object Object]
Pituitary MRI ,[object Object],[object Object],[object Object],[object Object]
 
Management ,[object Object],[object Object],[object Object],[object Object],[object Object]
Progress ,[object Object],[object Object],[object Object],[object Object]
Differential diagnosis of polydipsia/polyuria ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Causes of cranial DI ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Investigations ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Water deprivation test ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Treatment ,[object Object],[object Object],[object Object],[object Object],[object Object]
Conclusions ,[object Object],[object Object],[object Object],[object Object]

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Diabetes Insipidus