1. Chemotherapeutic agents
PRESENTED TO: MAM TAHIRA SAMAN

2. Key points
 Antibiotics
 Classification
 On the basis of mode of action
 On the basis of spectrum
 On the basis of mechanism of Action
 Resistance & cross Resistance

3. On the basis of mode of action
Cell wall synthesis
inhibitor
DNA Synthesis
inhibitor
Protein synthesis
inhibitor
RNA synthesis
inhibitor
Mycolic Acid
synthesis inhibitor
Folic acid
synthesis inhibitor

4. On the basis of mechanism of action:

5. Cell wall synthesis inhibitors

6. DNA RNA synthesis inhibitors

7. Protien Synthesis inhibitors

8. Antimycobacterial Classification

9. Folic acid synthesis inhibitors

10. On the basis of spectrum activity :
Broad spectrum antibiotics :
• Amoxicillin
• Tetracycline
• cephalosporin
• Chlorampenicol
• Erythromycin
Short spectrum antibiotics:
• Penicillin –G
• Cloxacillin
• vancomycin
• Bacitracin
• Fluxacillin

11. On the basis of mode of action:
Bacteriostatic antibiotics
• Tetracycline
• Chlorampenicol
• Erythromycin
• Lincomycin
Bacteriocidal antibiotics
• Cephalosporin
• Penicillin
• Erythromycin
• Aminoglycosides
• Cotrimoxazole

12. Antibiotics indications:
Pneumonia
Sepsis
Meningitis
Osteomyelitis
Urinogenital Infections
Gall Infections
Quinsy
Skin Infections
Mucous Membrane Infections
Scarlet Fever
Diphtheria
Siberian Ulcer
Gynecologic Infections
Syphilis
Respiratory Infections
ENT Infections
Fungous Infections

14. ARV therapy

15. Cancer chemotherapy