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Welcome to our
presentation
Presentation topic: Ebastine BP
Presented by:
Rana Ahmed (PHA-14001)
Mahfujul Hasan (PHA-14002)
Nasim Ahmed (PHA-14013)
Faisal Amin Anik (PHA-14014)
Md. Shydhur Rahman Chowdury (PHA-14015)
INTRODUCTION
Brand name: Ebast
Generic name: Ebastine BP
Ebast is a second-generation H1 receptor blocker.
It is an non-sedative antihistamine.
MBSTU PHARMACEUTICAL Ltd.
Mechanism of action
Ebastine
Blocking H-1 receptors
Antagonise all actions of Histamine
Available dosage forms
Tablet, Capsule, Syrup
DOSE
Physical
state
Dose Frequency Route Instruction
Adult dose 10-20 mg 24 hourly Oral
Pediatric dose 5 mg 24 hourly Oral Not recommended
below 6 years
Indications
 Seasonal allergic rhinitis
 Idiopathic chronic urticaria
 T cell mediated allergic inflammatory disorders (asthma, atopic dermatitis)
 T cell mediated autoimmune diseases
Side Effects
 Headache
 Dry mouth
 Abdominal pain
 Dyspepsia
 Asthenia
 Nausea
 Insomnia
Contra-indications
 Hypersensitivity
 Cardiac arrhythmia
Precautions and warnings
 Hepatic and renal insufficiency.
 Pregnancy, lactation.
Superiority than other antihistamines
 Long acting.
 Taken with or without food
 No psychomotor impairment-driving etc. can be allowed.
 Additional anti-allergic – LT and PAF inhibitor.
 Does not cross the BBB, so no sedation effect.
 Less side effects than first generation (fatigue, hyperactivity, convulsion).
 Effective than other second generation anti-histamines.
Levocetrizine Ebastine
Response
Log con.
.
Thank you

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Printed promotion material of Ebastine

  • 1. Welcome to our presentation Presentation topic: Ebastine BP Presented by: Rana Ahmed (PHA-14001) Mahfujul Hasan (PHA-14002) Nasim Ahmed (PHA-14013) Faisal Amin Anik (PHA-14014) Md. Shydhur Rahman Chowdury (PHA-14015)
  • 2. INTRODUCTION Brand name: Ebast Generic name: Ebastine BP Ebast is a second-generation H1 receptor blocker. It is an non-sedative antihistamine. MBSTU PHARMACEUTICAL Ltd.
  • 3. Mechanism of action Ebastine Blocking H-1 receptors Antagonise all actions of Histamine Available dosage forms Tablet, Capsule, Syrup DOSE Physical state Dose Frequency Route Instruction Adult dose 10-20 mg 24 hourly Oral Pediatric dose 5 mg 24 hourly Oral Not recommended below 6 years
  • 4. Indications  Seasonal allergic rhinitis  Idiopathic chronic urticaria  T cell mediated allergic inflammatory disorders (asthma, atopic dermatitis)  T cell mediated autoimmune diseases Side Effects  Headache  Dry mouth  Abdominal pain  Dyspepsia  Asthenia  Nausea  Insomnia Contra-indications  Hypersensitivity  Cardiac arrhythmia Precautions and warnings  Hepatic and renal insufficiency.  Pregnancy, lactation.
  • 5. Superiority than other antihistamines  Long acting.  Taken with or without food  No psychomotor impairment-driving etc. can be allowed.  Additional anti-allergic – LT and PAF inhibitor.  Does not cross the BBB, so no sedation effect.  Less side effects than first generation (fatigue, hyperactivity, convulsion).  Effective than other second generation anti-histamines. Levocetrizine Ebastine Response Log con.