1. Preclinical Imaging Centre
Centrum voor preklinische imaging van het Radboud UMC
Prof. dr. Otto C. Boerman
Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands
2. RTM: Radboud Translational Medicine
Discovery
Screening
preclinical testing
Clinical trials
Radboud University Nijmegen Medical Centre, The Netherlands
3. RTM: Radboud Translational Medicine
Discovery
Screening
preclinical testing
Clinical trials
Radboud University Nijmegen Medical Centre, The Netherlands
4. Radboudumc Technology Centres
Alain van Gool
Bioinformatics
Flow
cytometry
Preclinical
pharmacology
Proteomics
Metabolomics
Glycomics
Genetics
Otto Boerman
Preclinical
Imaging
Radboudumc
Technology
Centers
Big Data
Robotic
operations
Microscopy
Clinical
trials
Cleanrooms
Malaria lab
Neuroscience
unit
Biobank
7. From human imaging to small animal imaging
Mouse
Human
Uptake of 123I-IBF
by D2 receptors
Neurology
Dopamine w/ 99mTc-TRODAT
99mTc-MIBI
Cardiovascular
Stress 99mTc-MIBI
[99mTc] Minigastrin
Oncology
*functional imaging
Renal Cell Carcinoma
16. FDG-PET: functional imaging
Monitor response to treatment
Pre treatment
4 weeks after
start of treatment
24 weeks after
start of treatment
Pre treatment
Dept. Nuclear Medicine, Radboud University Nijmegen Medical Centre
17. FDG-PET: functional imaging
Monitor response to treatment
Pre treatment
4 weeks after
start of treatment
24 weeks after
start of treatment
Pre treatment
1 week after start of
imatinib treatment
Dept. Nuclear Medicine, Radboud University Nijmegen Medical Centre
18. FDG-PET: functional imaging
Monitor response to treatment
Pre treatment
4 weeks after
start of treatment
24 weeks after
start of treatment
Pre treatment
1 week after start of
imatinib treatment
Dept. Nuclear Medicine, Radboud University Nijmegen Medical Centre
28. Imaging transplated islets of Langerhans
Diabetes type 1: autoimmune destruction of insulin producing beta cells
Islet transplantation is a promising treatment for patients with type1 diabetes
AIM: Non-invasive in vivo determination of beta cell mass after islet transplantation.
In-111-DTPA-Exendin
islets
Radboud University Nijmegen Medical Centre, The Netherlands
39. Drug development Research
Hoffmann La Roche
Novartis
Sanofi
Fuji Biotechnology
Future Chemistry
Immunomedics Inc.
Synaffix
Wilex
Milabs
Radboud University Nijmegen Medical Centre, The Netherlands
