2. Definition
• Peripheral vascular disease (PVD) is a slow
and progressive circulation disorder caused
by narrowing, blockage, or spasms in a
blood vessel
• PVD may involve disease in any of the blood
vessels outside of the heart including the
arteries, veins, or lymphatic vessels
3. ETIOLOGY AND RISK FACTORS
Primarily caused by atherosclerosis
Embolism
Thrombosis
Trauma
Vasospasm
Inflammation
Family history
Sedentary lifestyle
Stress
Autoimmunity
Smoking
Hypertension
obesity
4. Pathophysiology
Risk factors
↑ Blood cholesterol
Plaque formation on intimal wall that causes partial or
complete occlusion
Calcification of medial layer and gradual loss of elasticity
Weakening of arterial wall
Predisposes to aneuryms, dilation or thrombus formation
Unable to transport adequate blood & O₂ to tissues during
exercise and rest leading to appearance of symptoms
7. Thromboangitis obliterans
1. Acute inflammatory lesions and occlusive
thrombosis of the arteries and veins
2. Strong association with smoking
3. Commonly occurs in male between 20-40yrs
8.
9. CLINICAL MANIFESTATIONS OF
THROMBOANGITIS OBLITERANS
Intermittent claudication
Pain during rest
Coldness
Paresthesia
Weak or absent pulse in posterior tibial, dorsalis
pedis
Extremities are cyanotic
Ulceration and gangrene
10. INTERVENTIONS
Advise patient to stop smoking
Avoid trauma
Emotional support
Avoid injuries to feet
Amputation of leg is done only when
Gangrene extends well into foot
Pain is severe
Severe infection
11. RAYNAUDS DISEASE
Intermittent episodes during which small arteries of
left or right arm constrict causing changes in skin
color & temperature
Symmetric bilateral involvement & may affect only
1or 2 fingers
May occur after exposure to cold, trauma
Characterised by reduction of blood flow to fingers
manifested by pallor
14. CLINICAL MANIFESTATIONS OF
RAYNAUDS DISEASE
During arterial spasm-sluggish blood flow occurs
Following the spasm the area becomes reddened
with tingling & throbbing sensation
With longstanding raynaud’s disease-ulcerations
can develop on fingertips & toes
16. ANEURYSM
• Is a localized or diffuse enlargement of an
artery at some point along its course
• Can occur when the vessel becomes
weakened from trauma, congenital vascular
disease, infection or atherosclerosis
17. TYPES OF ANEURYSM
• Saccular aneurysm – involves only part of the
circumference of the artery
• Fusiform aneurysm – spindle shaped, involves the
entire circumference of the arterial wall
• Dissecting aneurysm – involves hemorrhage into a
vessel wall, which splits and dissects the wall
causing a widening of the vessel
• caused by degenerative defect in the tunica media
and tunica intima
18.
19. DIAGNOSTIC TESTS
• CHEST & ABDOMINAL X-RAYS – helpful in
preliminary diagnosis of aortic aneurysm
• ULTRASOUND – is useful in determining the
size, shape and location of the aneurysm
• CT & MRA
20. THORACIC AORTIC ANEURYSM
Aneurysm in the thoracic area
Can develop in the ascending, transverse or
descending aorta
S/Sx
• Chest pain
• Cough
• Dyspnea
• Hoarseness
• Dysphagia
21. ABDOMINAL AORTIC ANEURYSM
Abdominal aorta below the renal arteries
S/Sx:
• Pulsatile abdominal mass on palpation
• Pain or tenderness in the mid-or upper abdomen
• The aneurysm may extend to impinge on the renal,
iliac, or mesenteric arteries
• Stasis of blood favors thrombus formation along the
wall of the vessel
22.
23. COMPLICATIONS
• Rupture of the aneurysm – most feared
complication
can occur if the aneurysm is large
• can lead to death
• Tx: Surgery – resection of the lesion and
replacement with a graft
24. Arterial Embolism
• Blood clots floating in the circulating arterial
blood
• The embolus is frequently a fragment of
arterioschlerotic plaque loosened from the
aorta
• Emboli will tend to lodge in femoral or
popliteal arteries, blood flow is impaired and
ischemia develops
25.
26. CLINICAL MANIFESTATIONS
• Abrupt onset of severe pain
• Muscular weakness and burning, aching pain
• Distal pulses are absent and extremity becomes
cold, numb and pale
• Symptoms of shock may develop
27. DEEP VEIN THROMBOSIS (DVT)
• Tends to occur at the deep veins due to stasis
of blood
• A major risk during the acute phase of
thrombophlebitis is dislodgment of the
thrombus
• Pulmonary embolus – is a serious
complication arising from DVT of the lower
extremities
28.
29. CLINICAL MANIFESTATIONS
• Pain and edema of extremity
• (+) Homan’s sign
• Do not check for the Homan’s sign if DVT is already
known to be present risk of embolus formation
• If superficial veins are affected redness, warmth,
tenderness will occur, the veins feel hard and
thready & sensitive to pressure
30. MEDICAL MANAGEMENT
• Requires hospitalization
• Bed rest with legs elevated to 15-20 degrees
• Application of warm moist heat to reduce pain
• Elastic stocking or bandage
• Anticoagulants, initially with IV heparin then Coumarin
• Fibrinolytic
• Vasodilator if needed to control vessel spasm
31. Assessment
• Condition of the skin: shiny, taut, absence of hair growth
• Ulcerations/ necrotic tissues
• Extremely cold to touch
• Peripheral pulses: diminished, weak, absent, bilateral inequality
• Grading 0 - absent
1 + weak & thready
2 + normal
3 + full & bounding
• Prolonged(> 3 secs) or absent capillary refill of nailbeds
• Loss of muscle tone or weakness
34. MEDICAL MANAGEMENT
• Weight reduction
• Exercise
• Stop smoking
• Blood lipid reduction
• Statins,Nicotinic acid, fibric acid derivative, bile acid
resins
• Promote arterial flow- Pentoxifylline
• Cilastazol – vasodilator & anti platelet
• Trendelenberg position
35. Surgical interventions
• Embolectomy
• Endartectomy is removal of a blood clot and stripping of
atherosclerotic plaque along with the inner arterial wall
• Arterial by-pass surgery- an obstructed arterial segment
may be by passed by using a prosthetic material( teflon) or
patient’s own artery or vein(saphenous vein)
• Percutaneous Transluminal Angioplasty- the balloon tip of
the catheter is inflated to provide compression of the
plaque
• Amputation
36. NURSING DIAGNOSIS
• Ineffective peripheral tissue perfusion
• Activity intolerance related to poor blood flow to
the lower extremities
• Ineffective health maintainance related to smoking
and lack of information about disease
• Risk for impaired skin integrity related to ischemic
tissues of legs and feet
37. FOOT CARE FOR PATIENTS WITHPERIPHERALATHEROSCLEROSIS
1. Keep legs & feet clean, dry & comfortable
o Clean with warm water & mild soap
o Pat dry using soft towel
o Apply cream after drying
o Wear a pair of cotton socks everyday
2. Prevent accidents and injuries to health
o Always wear shoes
o Walk on ground levels
o Don’t go barefoot
o Report if there is any foot problems
38. 3. Improve blood supply to legs & feet
o Don’t cross legs
o Don’t wear knee stockings
o Don’t swim in cold water
39. preventions
Do passive exercise of legs
Walk for atleast 30 mins daily
Avoid cold water for bathing
Stop smoking
If edema occurs, then elevate the legs
Dorsiflex legs at regular intervals to prevent venous
pooling
Avoid massaging the affected extremity
Keep extremity warm but do not heat
Use elastic stockings on affected leg