The document discusses micro/nano robotics in biomedical applications and its progress. It provides an introduction to micro/nano-robotics and its research background. It then discusses the research status of micro/nano-robotics at home and abroad over time. Various methods for controlling nano-robots are also presented, including magnetic field control, chemical gradient control, and bio-energy control. Potential biomedical applications of nano-robotics discussed include micro-invasive surgery, chromosome transplantation, artificial insemination, and cell manipulation. However, limitations such as controlling single structures accurately and possible allergic reactions are also noted. In conclusion, nano-robotics is seen as having huge potential for development in molecular medicine and

1. MICRO/NANO ROBOTICS
IN
BIOMEDICAL APPLICATIONS
AND ITS PROGRESSES
DATE : 17/2/2017
PRESENTED BY : SACHIN JOHN K
(TJANEEE018)

2. MICRO/NANO ROBOTICS IN BIOMEDICAL APPLICATIONS AND ITS PROGRESSES17/2/2017
CONTENTS

INTRODUCTION

THE RESEARCH BACKGROUND

RESEARCH STATUS AT HOME AND ABROAD

HOW AN NANO BOT IS MADE?

CONTROL TECHNOLOGY

APPLICATIONS IN BIOMEDICAL FIELD

LIMITATIONS

CONCLUSION
2

3. MICRO/NANO ROBOTICS IN BIOMEDICAL APPLICATIONS AND ITS PROGRESSES17/2/2017
INTRODUCTION

Micro/nano-robotics is an emerging robot research field which combines
with the special robotic technology.

Different from macroscopically visual robot, micro/nano-robots usually
refers to the microscopic systems scale.

This topic mainly deals with the applications of micro/nano robotics in
biomedical field and their limitations.
3

4. MICRO/NANO ROBOTICS IN BIOMEDICAL APPLICATIONS AND ITS PROGRESSES17/2/2017
THE
RESEARCH
BACKGROUN
D
4

5. MICRO/NANO ROBOTICS IN BIOMEDICAL APPLICATIONS AND ITS PROGRESSES17/2/2017
THE
LAWS
OF
PHYSICS
ARE NOT APPLICABLE IN
MICROSCOPIC LEVEL
5

6. MICRO/NANO ROBOTICS IN BIOMEDICAL APPLICATIONS AND ITS PROGRESSES17/2/2017
TYPICAL BACTERIA STRUCTURE
6

7. MICRO/NANO ROBOTICS IN BIOMEDICAL APPLICATIONS AND ITS PROGRESSES17/2/2017
TYPICAL BACTERIA STRUCTURE
FLAGELLA
7

8. MICRO/NANO ROBOTICS IN BIOMEDICAL APPLICATIONS AND ITS PROGRESSES17/2/2017
TYPICAL BACTERIA STRUCTURE
FLAGELLA
CILIA
8

9. MICRO/NANO ROBOTICS IN BIOMEDICAL APPLICATIONS AND ITS PROGRESSES17/2/2017
TYPICAL NANOBOT STRUCTURE
9

10. MICRO/NANO ROBOTICS IN BIOMEDICAL APPLICATIONS AND ITS PROGRESSES17/2/2017
TYPICAL NANOBOT STRUCTURE
FLAGELLA
10

11. MICRO/NANO ROBOTICS IN BIOMEDICAL APPLICATIONS AND ITS PROGRESSES17/2/2017
TYPICAL NANOBOT STRUCTURE
FLAGELLA
CILIA
11

12. MICRO/NANO ROBOTICS IN BIOMEDICAL APPLICATIONS AND ITS PROGRESSES17/2/2017
TYPICAL NANOBOT STRUCTURE
FLAGELLA
CILIA
SUCTION
CUP
12

13. MICRO/NANO ROBOTICS IN BIOMEDICAL APPLICATIONS AND ITS PROGRESSES17/2/2017
THE
RESEARCH
STATUS AT HOME AND ABROAD
13

14. MICRO/NANO ROBOTICS IN BIOMEDICAL APPLICATIONS AND ITS PROGRESSES17/2/2017
TIME LINE
14

15. MICRO/NANO ROBOTICS IN BIOMEDICAL APPLICATIONS AND ITS PROGRESSES17/2/2017
TIME LINE
2000
US NATIONAL
NANOTECHNOLOGY
INITIATIVE
15

16. MICRO/NANO ROBOTICS IN BIOMEDICAL APPLICATIONS AND ITS PROGRESSES17/2/2017
TIME LINE
2000
US NATIONAL
NANOTECHNOLOGY
INITIATIVE
2004
THE WORLDS FIRST
NANO BIPEDAL
ROBOT
16

17. MICRO/NANO ROBOTICS IN BIOMEDICAL APPLICATIONS AND ITS PROGRESSES17/2/2017
TIME LINE
2000
US NATIONAL
NANOTECHNOLOGY
INITIATIVE
2004
THE WORLDS FIRST
NANO BIPEDAL
ROBOT
2010
BULGARIA
DEVOLOPED
NANOBOTS FOR
ARTIFICIAL
INSEMINATION
17

18. MICRO/NANO ROBOTICS IN BIOMEDICAL APPLICATIONS AND ITS PROGRESSES17/2/2017
TIME LINE
2000
US NATIONAL
NANOTECHNOLOGY
INITIATIVE
2004
THE WORLDS FIRST
NANO BIPEDAL
ROBOT
2010
BULGARIA
DEVOLOPED
NANOBOTS FOR
ARTIFICIAL
INSEMINATION
2011
NANOBOTS
FOR TUMOR
TREATMENT
18

19. MICRO/NANO ROBOTICS IN BIOMEDICAL APPLICATIONS AND ITS PROGRESSES17/2/2017
TIME LINE
2000
US NATIONAL
NANOTECHNOLOGY
INITIATIVE
2004
THE WORLDS FIRST
NANO BIPEDAL
ROBOT
2010
BULGARIA
DEVOLOPED
NANOBOTS FOR
ARTIFICIAL
INSEMINATION
2011
NANOBOTS
FOR TUMOR
TREATMENT
2012
COMPUTER
MONITERED
NANOBOTS
19

20. MICRO/NANO ROBOTICS IN BIOMEDICAL APPLICATIONS AND ITS PROGRESSES17/2/2017
TIME LINE
2000
US NATIONAL
NANOTECHNOLOGY
INITIATIVE
2004
THE WORLDS FIRST
NANO BIPEDAL
ROBOT
2010
BULGARIA
DEVOLOPED
NANOBOTS FOR
ARTIFICIAL
INSEMINATION
2011
NANOBOTS
FOR TUMOR
TREATMENT
2012
COMPUTER
MONITERED
NANOBOTS
2015
NANOBOTS
MADE BY DNA
MOLECULES
20

21. MICRO/NANO ROBOTICS IN BIOMEDICAL APPLICATIONS AND ITS PROGRESSES17/2/2017
HOW
AN NANO-ROBOT IS MADE?

22. MICRO/NANO ROBOTICS IN BIOMEDICAL APPLICATIONS AND ITS PROGRESSES17/2/2017
PREPARATION
TECHNOLOGIES
22

23. MICRO/NANO ROBOTICS IN BIOMEDICAL APPLICATIONS AND ITS PROGRESSES17/2/2017
PREPARATION
TECHNOLOGIES
PHYSICAL
VAPOUR
DEPOSITION
Physical method
for the vacuum
condition and also the
basic method for
robots to acquire
magnetic which is for
environmental
Protection.
23

24. MICRO/NANO ROBOTICS IN BIOMEDICAL APPLICATIONS AND ITS PROGRESSES17/2/2017
PREPARATION
TECHNOLOGIES
PHYSICAL
VAPOUR
DEPOSITION
Physical method
for the vacuum
condition and also the
basic method for
robots to acquire
magnetic which is for
environmental
Protection.
CHEMICAL
VAPOUR
DEPOSITIO
N
Method of gas
phase layer deposition in the
fabrication of materials.
24

25. MICRO/NANO ROBOTICS IN BIOMEDICAL APPLICATIONS AND ITS PROGRESSES17/2/2017
PREPARATION
TECHNOLOGIES
PHYSICAL
VAPOUR
DEPOSITION
Physical method
for the vacuum
condition and also the
basic method for
robots to acquire
magnetic which is for
environmental
Protection.
CHEMICAL
VAPOUR
DEPOSITIO
N
Method of gas
phase layer deposition in the
fabrication of materials.
ELECTRO
CHEMICAL
DEPOSITION
Needed to be a template for
micro/nano-structure
then using direct current to
make magnetic material
restricted in micro/nano-
structure
25

26. MICRO/NANO ROBOTICS IN BIOMEDICAL APPLICATIONS AND ITS PROGRESSES17/2/2017
PREPARATION
TECHNOLOGIES
PHYSICAL
VAPOUR
DEPOSITION
Physical method
for the vacuum
condition and also the
basic method for
robots to acquire
magnetic which is for
environmental
Protection.
CHEMICAL
VAPOUR
DEPOSITIO
N
Method of gas
phase layer deposition in the
fabrication of materials.
ELECTRO
CHEMICAL
DEPOSITION
Needed to be a template for
micro/nano-structure
then using direct current to
make magnetic material
restricted in micro/nano-
structure
DIRECT
LASER
WRITING
Technology could make
Nanostructure of any
shapes on the
photoresist material
26

27. MICRO/NANO ROBOTICS IN BIOMEDICAL APPLICATIONS AND ITS PROGRESSES17/2/2017
CONTROL
TECHNOLOGY

28. MICRO/NANO ROBOTICS IN BIOMEDICAL APPLICATIONS AND ITS PROGRESSES17/2/2017
HOW NANO BOTS ARE CONTROLLED?
28

29. MICRO/NANO ROBOTICS IN BIOMEDICAL APPLICATIONS AND ITS PROGRESSES17/2/2017
MAGNETIC
FIELD
DRIVE
HOW NANO BOTS ARE CONTROLLED?
An external magnetic
field to produce such
a push force is
proved to be
effective
and controllable
29

30. MICRO/NANO ROBOTICS IN BIOMEDICAL APPLICATIONS AND ITS PROGRESSES17/2/2017
MAGNETIC
FIELD
DRIVE
CHEMICAL
GRADIENT
DRIVE
HOW NANO BOTS ARE CONTROLLED?
An external magnetic
field to produce such
a push force is
proved to be
effective
and controllable
According to the different
chemical gradients of
each region, the micro robot
will produce different
behaviors in different regions
30

31. MICRO/NANO ROBOTICS IN BIOMEDICAL APPLICATIONS AND ITS PROGRESSES17/2/2017
MAGNETIC
FIELD
DRIVE
CHEMICAL
GRADIENT
DRIVE
BIO-
ENERGY
DRIVE
HOW NANO BOTS ARE CONTROLLED?
An external magnetic
field to produce such
a push force is
proved to be
effective
and controllable
According to the different
chemical gradients of
each region, the micro robot
will produce different
behaviors in different regions
Nano bots are drived to the location
by the living system itself.
31

32. MICRO/NANO ROBOTICS IN BIOMEDICAL APPLICATIONS AND ITS PROGRESSES17/2/2017
MICRO/NANO-ROBOTICS
IN
BIOMEDICAL
TECHNOLOGY

33. MICRO/NANO ROBOTICS IN BIOMEDICAL APPLICATIONS AND ITS PROGRESSES17/2/2017
NANO
ROBOTICS
33

34. MICRO/NANO ROBOTICS IN BIOMEDICAL APPLICATIONS AND ITS PROGRESSES17/2/2017
NANO
ROBOTICS
MICRO-INVASIVE SURGERY
34

35. MICRO/NANO ROBOTICS IN BIOMEDICAL APPLICATIONS AND ITS PROGRESSES17/2/2017
NANO
ROBOTICS
MICRO-INVASIVE SURGERY
CHROMOSOME
TRANSPLANTATION
35

36. MICRO/NANO ROBOTICS IN BIOMEDICAL APPLICATIONS AND ITS PROGRESSES17/2/2017
NANO
ROBOTICS
MICRO-INVASIVE SURGERY
CHROMOSOME
TRANSPLANTATION
ARTIFICIAL
INSEMINATION
36

37. MICRO/NANO ROBOTICS IN BIOMEDICAL APPLICATIONS AND ITS PROGRESSES17/2/2017
NANO
ROBOTICS
MICRO-INVASIVE SURGERY
CHROMOSOME
TRANSPLANTATION
ARTIFICIAL
INSEMINATION
CELL
MANIPULATION
37

38. MICRO/NANO ROBOTICS IN BIOMEDICAL APPLICATIONS AND ITS PROGRESSES17/2/2017
NANO
ROBOTICS
MICRO-INVASIVE SURGERY
CHROMOSOME
TRANSPLANTATION
ARTIFICIAL
INSEMINATION
CELL
MANIPULATION CELL CLONING
38

39. MICRO/NANO ROBOTICS IN BIOMEDICAL APPLICATIONS AND ITS PROGRESSES17/2/2017
LIMITATIONS

Research is limited to single bionic structures.

Accurate,continous and low dimensional contol is still a challenge.

Possible allergic reactions from patients towards nanorobots.

Security and reliability.

Needs research on functionalization and intelligence of micro/nano
materials.
39

40. MICRO/NANO ROBOTICS IN BIOMEDICAL APPLICATIONS AND ITS PROGRESSES17/2/2017
CONCLUSION

Despite facing many challenges the future of nano robotics has
irreplacable advantages of devolopment.

Currently, micro/nano-robotics has been applied to the aspects of
molecular medicine, genetic engineering technology.

In addition, it has huge potential development directions in the future.
40

41. MICRO/NANO ROBOTICS IN BIOMEDICAL APPLICATIONS AND ITS PROGRESSES17/2/2017
REFERENCES
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458, pp. 1121-1122, 2009.
[2] A. A. Solovev, E. J. Smith, and C. C. Bof'Bufon, “Light-controlled
propulsion of catalytic microengines,” Angewandte Chemie
International Edition, vol. 50, pp. 10875-10878, 2011.
[3] P. Fischer and A. Ghosh, “Magnetically actuated propulsion at low
reynolds numbers: towards nanoscale control,” Nanoscale, vol. 3, pp.
557-563, 2011.
[4] W. Gao, S. Sattayasamitsathit, and K. M. Manesh, “Magnetically
powered flexible metal nanowire motors,” Journal of the American
Chemical Society, vol. 132, pp. 14403-14405, 2010.
[5] S. Balasubramanian, D. Kagan, and C. M. Hu, “Micromachineenabled
capture and isolation organization of cancer cells in complex
media,” Angewandte Chemie International Edition, vol. 50, pp. 4161-
4164, 2011.
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42. MICRO/NANO ROBOTICS IN BIOMEDICAL APPLICATIONS AND ITS PROGRESSES17/2/2017 42