1. By:
Sameen Jawed
Roll no: 66
4th year, 8th Semester

2. Portio vaginalis or
ectocervix
Ectocervix's
opening is called
the external os
Endocervical
canal
The endocervical
canal terminates
at the internal os
Transformation
zone

3.  Malignant neoplasm arising from the
cells originating in cervix uteri
 Common cause of death in developing
countries
 Occur in younger
women in child
bearing age

4.  Human papillomavirus (HPV) infection &
STDs
 Having many Sexual partners
 Smoking, alcohol, drug abuse
 Taking birth control pills
 Engaging in early sexual contact
 Multiparity with poor birth spacing
 Poor personal hygiene & socioeconomic
status
 Exposure to smegma

5.  Post coital vaginal bleeding
 Vaginal bleeding after menopause or
between periods
 Foul smelling watery discharge or
bloody vaginal discharge
 Pelvic pain
 Pain during coitus

6.  Cervical dysplasia leading to:
 CIN
 HSIL

8.  Squamous cell carcinoma (epidermoid carcinoma)
› Keratinising (well differentiated and moderately differentiated)
› non keratinising (large and small cell types)
› Spindle cell carcinoma
 Adenocarcinoma endocervical type
› Variant : adenoma malignum (minimal deviation carcinoma)
› Variant :villoglandular papillary adenocarcinoma
 Endometrioid adenocarcinoma
 Clear cell adenocarcinoma
 Serous adenocarcinoma
 Mesonephric adenocarcinoma
 Intestinal type (signet ring) adenocarcinoma
 Other epithelial tumours
› Adenosquamous carcinoma
› Adenoid cystic carcinoma
 Small cell carcinoma
 Undifferentiated carcinoma
 Metastatic tumours (breast, ovary, colon, and direct spread of endometrial
carcinoma)
Biblo: http://www.eurocytology.eu

11.  Lab test
Pap smear
Schiller’s iodine test
 Tissue sampling
Biopsy
 Cervical Examination
Colposcopy
Colpography

12.  Cone Biopsy
 Hysterectomy with lymph node
dissection
 Irradiation & Chemotherapy