5. 1.ATROPINE
• IT OCCURS AS COLORLESS CRYSTALS OR WHITE CRYSTALLINE POWDER.
• IT IS ODORLESS AND HAS BITTER TASTE
• SPARINGLY SOLUBLE IN WATER.
• FREELY SOLUBLE IN CHLOROFORM
• IN ACIDIC OR ALKALINE MEDIUM, IT IS HYDROLYZED TO GIVE TROPINE AND
TROPIC ACID.
6. USES
• IT IS USED TO TREAT PARKINSONISM
• IN SMALL DOSES, IT IS C.N.S STIMULANT
• AS A MYDRIATIC IN OPHTHALMOLOGY PRACTICE
• AS AN ANTISPASMODIC
• ATROPINE IS USED TO HELP REDUCE SALIVA, MUCUS, OR OTHER SECRETIONS
IN YOUR AIRWAY DURING A SURGERY.
7.
8. 2.HOMOTROPINE
• PROPERTIES
• IT OCCURS AS COLORLESS CRYSTALS OR WHITE CRYSTALLINE POWDER.
• IT IS ODORLESS AND HAS BITTER TASTE
• FREELY SOLUBLE IN WATER
• IN ACIDIC OR ALKALINE MEDIUM, IT IS HYDROLYZED TO GIVE TROPINE AND
MANDELIC ACID.
9.
10. 3.BENZTROPINE
• IT OCCURS AS WHITE CRYSTALLINE POWDER.
• IT IS ODORLESS AND HAS BITTER TASTE
• VERY SOLUBLE IN WATER.
• FREELY SOLUBLE IN ALCOHOL
• STABILITY AND STORAGE:
• IT IS HYGROSCOPIC ,HENCE STORED IN TIGHTLY CLOSED CONTAINERS.
11. • Uses :
• Benztropine is used to treat symptoms of Parkinson's disease
• helps decrease muscle stiffness, sweating, and the production
of saliva, and helps improve walking ability in people
with Parkinson's disease.
12. 4.HYOSCINE
• HYOSCINE, ALSO KNOWN AS SCOPOLAMINE
• IT OCCURS AS COLORLESS CRYSTALS OR WHITE CRYSTALLINE POWDER.
• IT IS ODORLESS
15. PROPERTIES
• IT OCCURS AS WHITE OR YELLOWISH WHITE POWDER.
• IT IS ODORLESS AND HAS BITTER TASTE
• IT IS SOLUBLE IN WATER.
• IT IS SLIGHTLY HYGROSCOPIC
• WHEN IT IS TREATED WITH SULPHURIC ACID, IT GIVES YELLOW SOLUTION
• STABILITY AND STORAGE:
• IT IS HYGROSCOPIC ,HENCE STORED IN TIGHTLY CLOSED CONTAINERS.
