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Wear of Knee Replacements  Influence of Kinematics and Design ,[object Object],[object Object],[object Object],[object Object],[object Object]
Two Types of Polyethylene Wear ,[object Object],[object Object]
Surface Wear in Knees ,[object Object],[object Object],[object Object]
Factors That Affect TKR Surface Wear in  Current  Polyethylenes ,[object Object],[object Object],[object Object]
Leeds ProSim Knee Simulator
Leeds ProSim Knee Simulator ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],Tibial Rotation AP Displacement Flexion/Extension Axial Force Abduction/Adduction Medial/Lateral Translation
Kinematic Inputs ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Effect of Bearing Materials  Fixed Bearing Knees - PFC, PFC Sigma ,[object Object],[object Object],[object Object],[object Object],[object Object]
Fixed Bearing Knees  PFC    - IR in air PFC Sigma    - IR under vacuum and foil packed PFC Sigma Marathon
Effect of Kinematics on Wear  Fixed Bearing Knees
Effect of Kinematics  Fixed Bearing Knees - PFC Sigma 1020 GVF
Fixed Bearing Knees  PFC Sigma 1020 GVF High Kinematics PFC Sigma 1020 GVF Intermediate Kinematics PFC Sigma 1020 GVF Low Kinematics McEwen et al J Biomechanics 2005
Effect of Kinematics  ,[object Object],[object Object],[object Object]
Fixed Bearing Knees ,[object Object],femoral rotation a-p translation tray femoral bearing flexion- extension
Molecular Strain Hardening ,[object Object],principle direction of sliding strain softening strain hardening ,[object Object]
Effect of Prosthesis Design
Effect of Prosthesis Design Fixed Bearing PFC Sigma Mobile Bearing PFC Sigma Rotating Platform ,[object Object],Fixed Bearing Mobile Bearing Rotating Platform
Fixed Bearing Knee PFC Sigma  Mobile Bearing Knee PFC Sigma RP Engineering Comparison: Matched Intermediate Kinematics McEwen et al, J Biomechanics 2005
Fixed Bearing Knee PFC Sigma  Mobile Bearing Knee PFC Sigma RP Clinical Comparison High Kinematics McEwen et al, J Biomechanics 2005
Mobile Bearing Knees ,[object Object],[object Object],[object Object],tibial rotation flexion- extension femoral bearing tray
Kinematics ,[object Object],[object Object],[object Object],wear rate unidirectional multidirectional Friction vectors Wear path —  transverse —  principal RP Fixed Hip  F FR  ,[object Object],[object Object],[object Object],[object Object]
Wear Debris Volumetric Concentration
Biological Activity and  Osteolytic Potential Tipper et al, Soc Biomaterials 2005 17.6 0.69 25.6 ± 5.3 Hip 1.8 0.36 5.2 ± 3.8 PFC Sigma RP 6.8 0.3 22.75 ± 5.95 PFC Sigma FBA Functional  Osteolytic  Potential SBA Specific  Biological Activity Mean Wear Rate (mm 3 /10 6  cycles) Implant Type
Knee Design ,[object Object],[object Object],[object Object],[object Object]
Lift Off ,[object Object],[object Object],[object Object],[object Object],Jennings et al ORS 2005
Effect of Lift Off   Fixed Bearing PFC Sigma Mobile Bearing PFC Sigma Rotating Platform p < 0.05 p < 0.05 p > 0.05
Lift off ,[object Object],[object Object],[object Object],[object Object]
Conclusions ,[object Object],[object Object],[object Object],[object Object]
Thank you Co authors Hannah McEwen, Petra Barnett, Carol Bell,  Amir Kamali, Dan Auger, Richard Farrar, Joanne Tipper, Alison Galvin,  Mark Taylor, Martin Stone, Eileen Ingham Research supported by  EPSRC, ARC, DePuy

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Jennings Lm. Wear Of Knee Replacements Influence Of Kinematics And Design

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  • 5. Leeds ProSim Knee Simulator
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  • 9. Fixed Bearing Knees PFC  - IR in air PFC Sigma  - IR under vacuum and foil packed PFC Sigma Marathon
  • 10. Effect of Kinematics on Wear Fixed Bearing Knees
  • 11. Effect of Kinematics Fixed Bearing Knees - PFC Sigma 1020 GVF
  • 12. Fixed Bearing Knees PFC Sigma 1020 GVF High Kinematics PFC Sigma 1020 GVF Intermediate Kinematics PFC Sigma 1020 GVF Low Kinematics McEwen et al J Biomechanics 2005
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  • 18. Fixed Bearing Knee PFC Sigma Mobile Bearing Knee PFC Sigma RP Engineering Comparison: Matched Intermediate Kinematics McEwen et al, J Biomechanics 2005
  • 19. Fixed Bearing Knee PFC Sigma Mobile Bearing Knee PFC Sigma RP Clinical Comparison High Kinematics McEwen et al, J Biomechanics 2005
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  • 22. Wear Debris Volumetric Concentration
  • 23. Biological Activity and Osteolytic Potential Tipper et al, Soc Biomaterials 2005 17.6 0.69 25.6 ± 5.3 Hip 1.8 0.36 5.2 ± 3.8 PFC Sigma RP 6.8 0.3 22.75 ± 5.95 PFC Sigma FBA Functional Osteolytic Potential SBA Specific Biological Activity Mean Wear Rate (mm 3 /10 6 cycles) Implant Type
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  • 26. Effect of Lift Off Fixed Bearing PFC Sigma Mobile Bearing PFC Sigma Rotating Platform p < 0.05 p < 0.05 p > 0.05
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  • 29. Thank you Co authors Hannah McEwen, Petra Barnett, Carol Bell, Amir Kamali, Dan Auger, Richard Farrar, Joanne Tipper, Alison Galvin, Mark Taylor, Martin Stone, Eileen Ingham Research supported by EPSRC, ARC, DePuy