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Rashes when to worry-----------?
D. TAREK SAYED
pediatric departement
MCH Buraydah

Rashes
When
To worry

Dr.Tarek Kotb
MCH
Buraydah


The differential diagnosis for febrile patients
with a rash is extensive.

The differential diagnosis for patient with rash is extensive
Rashes


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






Macule: nonpalpable, circumscribed, flat lesion (<1 cm in diameter)
Papule: palpable , elevated lesion (<1 cm in diameter)
Maculopapular: combination of macular and popular lesions
Purpura: non-blanching papules or macules due to extravasation of RBCs
Vesicle: fluid-filled, elevated skin lesion (<1 cm in diameter)
Bulla: fluid-filled, elevated skin lesion (>1 cm in diameter)
Pustule: pus-containing vesicle
Ulcer: depressed skin lesion with missing epidermis and upper layer of
dermis
causes
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


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

viruses
bacteria
infectious
Spirochetes
rickettsiae
Medications
rheumatologic diseases
Allergic

Non
infectios


Evaluating the
patient who
presents with fever
and a rash can be
challenging because
the differential
diagnosis is
extensive and
includes minor and
life-threatening
illnesses
Because the severity of
these illnesses can vary
from minor (roseola) to
life-threatening
(meningococcemia), the
physician must make
prompt management
decisions regarding
imperical theraby.
Age
Season
Geographic location
Exposures
Medications
immunization

Review for SLE

When started
Where started
Where spread

Review for IBD
Erythema nodosum
Pyderma gangrenosum

What was used
To treat ?
Podrome



Ringworm
Worms don't cause ringworm.
It's caused by a fungus that
lives off dead skin, hair, and
nail tissue. It starts as a red,
scaly patch or bump. Then
comes the telltale itchy red ring.
The ring has raised, blistery, or
scaly borders. Ringworm is
passed on by skin-to-skin
contact with a person or animal.
Kids can also get it by sharing
things like towels or sports
gear. You may treat it with
antifungal creams.



Fifth Disease
This contagious and usually mild
illness passes in a couple of
weeks. Fifth disease starts with
flu-like symptoms. A bright face
and body rash follow. It’s spread
by coughing and sneezing and
most contagious the week before
the rash appears. It's treated with
rest, fluids, and pain relievers (do
not give aspirin to children). If
your child has fifth disease and
you are pregnant, call your doctor.



Chickenpox
This once-common rash isn't seen
as much in today's kids thanks to
the chickenpox vaccine. It’s very
contagious, spreads easily, and
leaves an itchy rash and red spots
or blisters all over the body. The
spots go through stages. They
blister, burst, dry, and crust over.
Chickenpox can be very serious.
All young kids should get a
chickenpox vaccine. So should
teens and adults who never had it
or the shot.



Impetigo
Impetigo, caused by bacteria,
creates red sores or blisters.
These can break open, ooze, and
develop a yellow-brown crust.
Sores can show up all over the
body but mostly around the mouth
and nose. Impetigo can be spread
through close contact or by
sharing things like towels and
toys. Scratching can spread it to
other parts of the body. It's treated
with antibiotic ointment or pills.



Warts
A virus causes these funky but
mostly harmless, painless skin
growths. Warts can spread easily
from person to person. They also
spread by touching an object used
by a person with the virus. They're
most often found on fingers and
hands. To prevent warts from
spreading, tell your child not to
pick them or bite nails. Cover
warts with bandages. Most warts
go away on their own.



Contact Dermatitis
Some kids' skin reacts after
touching foods, soaps, or plants
like poison ivy, sumac, or oak. The
rash usually starts within 48 hours
after skin contact. Minor cases
may cause mild redness or a rash
of small red bumps. In severe
cases you may see swelling,
redness, and larger blisters. This
rash goes away after a week or
two or when contact ends.




Hand-Foot-Mouth Disease
(Coxsackie)
Despite its scary name, this is a
common childhood illness. It starts
with a fever, followed by painful
mouth sores and a non-itchy rash.
The rash blisters on hands, feet,
and sometimes buttocks and legs.
It spreads through coughing,
sneezing, and used diapers. So
wash hands often. Coxsackie isn’t
serious and usually goes away on
its own in about a week.



Eczema
Kids prone to eczema may have
other allergies and asthma. The
exact cause isn't clear. But kids
who get it tend to have a sensitive
immune system. Watch for a
raised rash with dry skin and
intense itching. Atopic dermatitis is
the most common type of eczema.
Some children outgrow it or have
milder cases as they get older.



Hives
Many things can trigger these itchy or
burning welts. Medicines such as
aspirin (which kids should never take)
and penicillin can set off hives. Food
triggers include eggs, nuts, shellfish,
and food additives. Heat or cold and
strep throat can also cause hives.
Welts can show up anywhere on the
body and last minutes or days.
Sometimes an antihistamine can help.
Hives can be a sign of serious
problems, especially when they come
with breathing troubles or swelling in
the face. In those cases or if hives
don't go away, see your doctor.



Scarlet Fever
Scarlet fever is strep throat with a
rash. Symptoms include sore
throat, fever, headache, belly
pain, and swollen neck glands.
After 1-2 days, a red rash with a
sandpaper texture shows up. After
7-14 days, the rash rubs
off. Scarlet fever is very
contagious, so wash hands often
to keep it from spreading. Call
your child's doctor if you think your
child has it. He'll probably be
treated with with antibiotics.



Roseola (Sixth Disease)
Roseola, a mild illness, gets its
nickname from a list of six
common childhood rashes. Young
kids 6 months to 2 years are most
likely to get it. It's rare after age 4.
It starts with a cold, followed by a
few days of high fever (which can
trigger seizures). Then the fevers
end suddenly. They're followed by
a rash of small, pink, flat, or
slightly raised bumps. It shows up
first on the chest and back, then
hands and feet.



Rubella (German Measles)
Rubella, also called German
measles, is a mild virus that
usually causes no serious
problems. However, it can harm
the fetus if a pregnant woman
becomes infected. The symptoms
are a low fever and rash that
spreads from the face to the rest
of the body. A standard childhood
vaccine called MMR protects
against measles, mumps, and
rubella.



Lyme Disease
The hallmark of Lyme disease is a
target-shaped rash that appears
1-2 weeks after a tick bite, though
not everyone will develop the
distinctive rash. The rash may be
accompanied by a fever, chills,
and body aches. The culprit is a
type of bacterium carried by tiny
deer ticks. Without treatment,
Lyme disease can affect the joints,
nervous system, and heart.



Molluscum Contagiosum
Signs: This contagious rash
shows up as one or more
flesh-colored, raised bumps
that are about the size of a
pimple. The center of each
bump has a tiny dimple. The
rash usually shows up on the
face, arms, and legs




Diaper Rash With Yeast
Infection
Signs: This red, raised rash
shows up in the groin, around
the genitals, in the creases of
the hips, or on the buttocks. It
itches or irritates. Signs of an
accompanying yeast infection
are round, red spots separate
from but near the main rash.



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

A young child presents to the
local ED with a fever, rash, and
lymphadenopathy. An
examination of his mouth
demonstrates a strawberry
tongue (shown here). You
suspect Kawasaki disease and
tell the parents that he is most
likely to suffer long-term
complications in which organ
system?
A. Cardiovascular
B. Neurologic
C. Gastrointestinal
D. Musculoskeletal
E. Pulmonary


The correct answer is A. Kawasaki
disease is an acute febrile vasculitis
of unknown etiology. Epidemics in
young children occur in the late
winter and spring, with the highest
incidence among individuals of
Japanese descent. There are 3
distinct stages. In the acute stage
(1-11 days), patients develop high
fevers (> 100 F), ocular changes
(conjunctivitis, anterior uveitis),
perianal erythema, acral edema and
erythema, oropharyngeal changes
(strawberry tongue, hyperemia,
fissuring), and lymphadenopathy. In
the subacute stage (11-30 days),
there may be persistent irritability,
anorexia, conjunctival injection,
thrombocytosis, acral
desquamation (shown), and
aneurysmal formation.
•

•

•

•

•

•

A child is brought into his pediatrician's
office after developing a diffuse rash.
His parents do not believe in
vaccinations. You suspect that the
child has developed measles. All of the
following are true about measles
EXCEPT:
A. Measles is a leading cause of death
in young children worldwide
B. The classic triad is
cough, coryza, and conjunctivitis
C. Koplik spots are pathognomonic
white spots that appear on the buccal
cheeks
D. A major early complication is acute
sclerosing panencephalitis
E. Since the introduction of the
measles vaccine, the annual incidence
dramatically decreased.




Measles is one of the most contagious
infectious diseases, with a secondary
infection rate of 90% in susceptible
individuals
it remains one of the leading causes of
death in young children worldwide,
with an estimated 197,000 deaths
yearly. After exposure, the incubation
period lasts for 7-14 days. Patients
then develop a prodrome of high
fevers, often > 104 F, with the classic
triad of cough, coryza, and
conjunctivitis. A couple of days later,
Koplik spots develop on the buccal
mucosa, appearing as white spots on
an erythematous base, as shown.
o

o
o

o

o

o

A 4-month-old girl presents to the
ED in extremis with rapidly
developing gangrene of the
extremities. All of the following are
true of meningococcemia
EXCEPT:
A. The mortality rate is 5%-10%
B. Meningitis is present in all
cases of septicemia
C. Empiric antibiotic treatment
should be initiated immediately
D. Transmission is person-toperson by direct contact via
respiratory droplets
E. Gangrene is caused by arterial
occlusion



The correct answer is B
Meningococcemia is caused by the
gram-negative diplococcusNeisseria
meningitides. Transmission is personto-person via respiratory droplets,
often from an asymptomatic carrier.
Up to 30% of teenagers and 10% of
adults carry meningococci in the upper
respiratory tract. The clinical
presentation is variable, with 50% of
patients developing meningitis only,
10% developing septicemia only, and
40% developing both. Children with
meningitis are usually febrile and illappearing, with symptoms of lethargy,
vomiting, or nuchal rigidity. Septicemia
leads to capillary leak, coagulopathy,
profound acidosis, and myocardial
failure. Septic emboli cause arterial
occlusion in the distal extremities, as
shown in this infant.











An 11-year-old girl presents with
raised violaceous plaques on her legs
and arms that developed over the last
few days. She has had a temperature
of 100-101 F at home but no other
complaints. Her current temperature is
100.2 F. The rest of her exam is
normal. You conclude that she has
Henoch-Schonlein purpura (HSP).
Which of the following tests are most
appropriate to perform at this point?
A. CBC, lumbar puncture
B. CBC, electrolytes, stool for occult
blood, urinalysis
C. CBC, electrolytes, stool for occult
blood, renal ultrasound
D. CBC, head CT, lumbar puncture,
abdominal ultrasound
E. CBC, abdominal ultrasound


The correct answer is B. The images
shown are purpuric lesions. In this
case of a healthy-appearing child with
this history and physical examination,
HSP is a reasonable diagnosis. HSP is
a vasculitis that can affect the skin,
joints, gastrointestinal tract, and
kidneys. In a well-appearing child,
HSP can be managed on an outpatient
basis. It is helpful to check blood
pressure, urine, and electrolytes to
look for a glomerulonephritis.
Urinalysis and blood pressure may be
followed for several months to monitor
kidney function. A fecal occult blood
test can help rule out significant gut
involvement, especially in children with
pain. Intussusception is the most
serious complication of HSP; if it is
suspected, the child should be
admitted and monitored.
A 3-year-old girl presents with a blistering
rash on her face and body. Her mouth is
pictured above. All of the following are true
statements regarding Stevens-Johnson
syndrome (SJS) EXCEPT:
A. Medications, including nonsteroidal
anti-inflammatory medications (NSAIDs),
sulfonamides, antiepileptics, and
allopurinol, are commonly accepted
triggers
B. Viruses, such as herpes simplex virus,
Epstein-Barr virus, enteroviruses, and
influenza, are accepted triggers
C. Malignancy can be associated with SJS
D. Bacterial etiologies include
mycoplasma and group A beta-hemolytic
streptococcus, among others
E. Idiopathic causes are unlikely



The correct answer is E.
SJS may involve the mucous
membranes, including the eyes and
gastrointestinal tract. When more than
30% of the body surface area is
involved, cases are generally referred
to as toxic epidermal necrolysis.
Treatment is symptomatic, including
treatment of superinfection and pain
control. Patients with severe cases
should immediately be fluidresuscitated and treated as burn
victims. Offending agents should be
removed or treated. Use of steroids is
controversial. Involvement of
specialists, including ophthalmologists,
immunologists, and burn specialists,
may be indicated. Morbidity and
mortality are correlated with the
percentage of body surface area
involved


Staphylococcal scalded skin
syndrome (SSSS) is a disease
that usually affects infants and
young children who lack the
antibodies to Staphylococcus
aureus toxins that adults have. It
is caused by bacterial infection by
group II S. aureus that produces
toxins that cause
exfoliation, bullae (blister)
formation and redness of skin. In
children mortality is low, but can
be high in adults, who will usually
have a serious underlying disease
that makes them susceptible to
infection
Thank you

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rashes when to worry

  • 1. Rashes when to worry-----------? D. TAREK SAYED pediatric departement MCH Buraydah Rashes When To worry Dr.Tarek Kotb MCH Buraydah
  • 2.  The differential diagnosis for febrile patients with a rash is extensive. The differential diagnosis for patient with rash is extensive
  • 3. Rashes          Macule: nonpalpable, circumscribed, flat lesion (<1 cm in diameter) Papule: palpable , elevated lesion (<1 cm in diameter) Maculopapular: combination of macular and popular lesions Purpura: non-blanching papules or macules due to extravasation of RBCs Vesicle: fluid-filled, elevated skin lesion (<1 cm in diameter) Bulla: fluid-filled, elevated skin lesion (>1 cm in diameter) Pustule: pus-containing vesicle Ulcer: depressed skin lesion with missing epidermis and upper layer of dermis
  • 5.  Evaluating the patient who presents with fever and a rash can be challenging because the differential diagnosis is extensive and includes minor and life-threatening illnesses
  • 6. Because the severity of these illnesses can vary from minor (roseola) to life-threatening (meningococcemia), the physician must make prompt management decisions regarding imperical theraby.
  • 7. Age Season Geographic location Exposures Medications immunization Review for SLE When started Where started Where spread Review for IBD Erythema nodosum Pyderma gangrenosum What was used To treat ? Podrome
  • 8.   Ringworm Worms don't cause ringworm. It's caused by a fungus that lives off dead skin, hair, and nail tissue. It starts as a red, scaly patch or bump. Then comes the telltale itchy red ring. The ring has raised, blistery, or scaly borders. Ringworm is passed on by skin-to-skin contact with a person or animal. Kids can also get it by sharing things like towels or sports gear. You may treat it with antifungal creams.
  • 9.   Fifth Disease This contagious and usually mild illness passes in a couple of weeks. Fifth disease starts with flu-like symptoms. A bright face and body rash follow. It’s spread by coughing and sneezing and most contagious the week before the rash appears. It's treated with rest, fluids, and pain relievers (do not give aspirin to children). If your child has fifth disease and you are pregnant, call your doctor.
  • 10.   Chickenpox This once-common rash isn't seen as much in today's kids thanks to the chickenpox vaccine. It’s very contagious, spreads easily, and leaves an itchy rash and red spots or blisters all over the body. The spots go through stages. They blister, burst, dry, and crust over. Chickenpox can be very serious. All young kids should get a chickenpox vaccine. So should teens and adults who never had it or the shot.
  • 11.   Impetigo Impetigo, caused by bacteria, creates red sores or blisters. These can break open, ooze, and develop a yellow-brown crust. Sores can show up all over the body but mostly around the mouth and nose. Impetigo can be spread through close contact or by sharing things like towels and toys. Scratching can spread it to other parts of the body. It's treated with antibiotic ointment or pills.
  • 12.   Warts A virus causes these funky but mostly harmless, painless skin growths. Warts can spread easily from person to person. They also spread by touching an object used by a person with the virus. They're most often found on fingers and hands. To prevent warts from spreading, tell your child not to pick them or bite nails. Cover warts with bandages. Most warts go away on their own.
  • 13.   Contact Dermatitis Some kids' skin reacts after touching foods, soaps, or plants like poison ivy, sumac, or oak. The rash usually starts within 48 hours after skin contact. Minor cases may cause mild redness or a rash of small red bumps. In severe cases you may see swelling, redness, and larger blisters. This rash goes away after a week or two or when contact ends.
  • 14.   Hand-Foot-Mouth Disease (Coxsackie) Despite its scary name, this is a common childhood illness. It starts with a fever, followed by painful mouth sores and a non-itchy rash. The rash blisters on hands, feet, and sometimes buttocks and legs. It spreads through coughing, sneezing, and used diapers. So wash hands often. Coxsackie isn’t serious and usually goes away on its own in about a week.
  • 15.   Eczema Kids prone to eczema may have other allergies and asthma. The exact cause isn't clear. But kids who get it tend to have a sensitive immune system. Watch for a raised rash with dry skin and intense itching. Atopic dermatitis is the most common type of eczema. Some children outgrow it or have milder cases as they get older.
  • 16.   Hives Many things can trigger these itchy or burning welts. Medicines such as aspirin (which kids should never take) and penicillin can set off hives. Food triggers include eggs, nuts, shellfish, and food additives. Heat or cold and strep throat can also cause hives. Welts can show up anywhere on the body and last minutes or days. Sometimes an antihistamine can help. Hives can be a sign of serious problems, especially when they come with breathing troubles or swelling in the face. In those cases or if hives don't go away, see your doctor.
  • 17.   Scarlet Fever Scarlet fever is strep throat with a rash. Symptoms include sore throat, fever, headache, belly pain, and swollen neck glands. After 1-2 days, a red rash with a sandpaper texture shows up. After 7-14 days, the rash rubs off. Scarlet fever is very contagious, so wash hands often to keep it from spreading. Call your child's doctor if you think your child has it. He'll probably be treated with with antibiotics.
  • 18.   Roseola (Sixth Disease) Roseola, a mild illness, gets its nickname from a list of six common childhood rashes. Young kids 6 months to 2 years are most likely to get it. It's rare after age 4. It starts with a cold, followed by a few days of high fever (which can trigger seizures). Then the fevers end suddenly. They're followed by a rash of small, pink, flat, or slightly raised bumps. It shows up first on the chest and back, then hands and feet.
  • 19.   Rubella (German Measles) Rubella, also called German measles, is a mild virus that usually causes no serious problems. However, it can harm the fetus if a pregnant woman becomes infected. The symptoms are a low fever and rash that spreads from the face to the rest of the body. A standard childhood vaccine called MMR protects against measles, mumps, and rubella.
  • 20.   Lyme Disease The hallmark of Lyme disease is a target-shaped rash that appears 1-2 weeks after a tick bite, though not everyone will develop the distinctive rash. The rash may be accompanied by a fever, chills, and body aches. The culprit is a type of bacterium carried by tiny deer ticks. Without treatment, Lyme disease can affect the joints, nervous system, and heart.
  • 21.   Molluscum Contagiosum Signs: This contagious rash shows up as one or more flesh-colored, raised bumps that are about the size of a pimple. The center of each bump has a tiny dimple. The rash usually shows up on the face, arms, and legs
  • 22.   Diaper Rash With Yeast Infection Signs: This red, raised rash shows up in the groin, around the genitals, in the creases of the hips, or on the buttocks. It itches or irritates. Signs of an accompanying yeast infection are round, red spots separate from but near the main rash.
  • 23.
  • 24.
  • 25.       A young child presents to the local ED with a fever, rash, and lymphadenopathy. An examination of his mouth demonstrates a strawberry tongue (shown here). You suspect Kawasaki disease and tell the parents that he is most likely to suffer long-term complications in which organ system? A. Cardiovascular B. Neurologic C. Gastrointestinal D. Musculoskeletal E. Pulmonary
  • 26.  The correct answer is A. Kawasaki disease is an acute febrile vasculitis of unknown etiology. Epidemics in young children occur in the late winter and spring, with the highest incidence among individuals of Japanese descent. There are 3 distinct stages. In the acute stage (1-11 days), patients develop high fevers (> 100 F), ocular changes (conjunctivitis, anterior uveitis), perianal erythema, acral edema and erythema, oropharyngeal changes (strawberry tongue, hyperemia, fissuring), and lymphadenopathy. In the subacute stage (11-30 days), there may be persistent irritability, anorexia, conjunctival injection, thrombocytosis, acral desquamation (shown), and aneurysmal formation.
  • 27. • • • • • • A child is brought into his pediatrician's office after developing a diffuse rash. His parents do not believe in vaccinations. You suspect that the child has developed measles. All of the following are true about measles EXCEPT: A. Measles is a leading cause of death in young children worldwide B. The classic triad is cough, coryza, and conjunctivitis C. Koplik spots are pathognomonic white spots that appear on the buccal cheeks D. A major early complication is acute sclerosing panencephalitis E. Since the introduction of the measles vaccine, the annual incidence dramatically decreased.
  • 28.   Measles is one of the most contagious infectious diseases, with a secondary infection rate of 90% in susceptible individuals it remains one of the leading causes of death in young children worldwide, with an estimated 197,000 deaths yearly. After exposure, the incubation period lasts for 7-14 days. Patients then develop a prodrome of high fevers, often > 104 F, with the classic triad of cough, coryza, and conjunctivitis. A couple of days later, Koplik spots develop on the buccal mucosa, appearing as white spots on an erythematous base, as shown.
  • 29. o o o o o o A 4-month-old girl presents to the ED in extremis with rapidly developing gangrene of the extremities. All of the following are true of meningococcemia EXCEPT: A. The mortality rate is 5%-10% B. Meningitis is present in all cases of septicemia C. Empiric antibiotic treatment should be initiated immediately D. Transmission is person-toperson by direct contact via respiratory droplets E. Gangrene is caused by arterial occlusion
  • 30.   The correct answer is B Meningococcemia is caused by the gram-negative diplococcusNeisseria meningitides. Transmission is personto-person via respiratory droplets, often from an asymptomatic carrier. Up to 30% of teenagers and 10% of adults carry meningococci in the upper respiratory tract. The clinical presentation is variable, with 50% of patients developing meningitis only, 10% developing septicemia only, and 40% developing both. Children with meningitis are usually febrile and illappearing, with symptoms of lethargy, vomiting, or nuchal rigidity. Septicemia leads to capillary leak, coagulopathy, profound acidosis, and myocardial failure. Septic emboli cause arterial occlusion in the distal extremities, as shown in this infant.
  • 31.       An 11-year-old girl presents with raised violaceous plaques on her legs and arms that developed over the last few days. She has had a temperature of 100-101 F at home but no other complaints. Her current temperature is 100.2 F. The rest of her exam is normal. You conclude that she has Henoch-Schonlein purpura (HSP). Which of the following tests are most appropriate to perform at this point? A. CBC, lumbar puncture B. CBC, electrolytes, stool for occult blood, urinalysis C. CBC, electrolytes, stool for occult blood, renal ultrasound D. CBC, head CT, lumbar puncture, abdominal ultrasound E. CBC, abdominal ultrasound
  • 32.  The correct answer is B. The images shown are purpuric lesions. In this case of a healthy-appearing child with this history and physical examination, HSP is a reasonable diagnosis. HSP is a vasculitis that can affect the skin, joints, gastrointestinal tract, and kidneys. In a well-appearing child, HSP can be managed on an outpatient basis. It is helpful to check blood pressure, urine, and electrolytes to look for a glomerulonephritis. Urinalysis and blood pressure may be followed for several months to monitor kidney function. A fecal occult blood test can help rule out significant gut involvement, especially in children with pain. Intussusception is the most serious complication of HSP; if it is suspected, the child should be admitted and monitored.
  • 33. A 3-year-old girl presents with a blistering rash on her face and body. Her mouth is pictured above. All of the following are true statements regarding Stevens-Johnson syndrome (SJS) EXCEPT: A. Medications, including nonsteroidal anti-inflammatory medications (NSAIDs), sulfonamides, antiepileptics, and allopurinol, are commonly accepted triggers B. Viruses, such as herpes simplex virus, Epstein-Barr virus, enteroviruses, and influenza, are accepted triggers C. Malignancy can be associated with SJS D. Bacterial etiologies include mycoplasma and group A beta-hemolytic streptococcus, among others E. Idiopathic causes are unlikely
  • 34.   The correct answer is E. SJS may involve the mucous membranes, including the eyes and gastrointestinal tract. When more than 30% of the body surface area is involved, cases are generally referred to as toxic epidermal necrolysis. Treatment is symptomatic, including treatment of superinfection and pain control. Patients with severe cases should immediately be fluidresuscitated and treated as burn victims. Offending agents should be removed or treated. Use of steroids is controversial. Involvement of specialists, including ophthalmologists, immunologists, and burn specialists, may be indicated. Morbidity and mortality are correlated with the percentage of body surface area involved
  • 35.  Staphylococcal scalded skin syndrome (SSSS) is a disease that usually affects infants and young children who lack the antibodies to Staphylococcus aureus toxins that adults have. It is caused by bacterial infection by group II S. aureus that produces toxins that cause exfoliation, bullae (blister) formation and redness of skin. In children mortality is low, but can be high in adults, who will usually have a serious underlying disease that makes them susceptible to infection

Editor's Notes

  1. 1—measles 2- scarlet 3-rubella 4- staph 5- erythema inectiosum 6- roseola hsv6