SFS isa novel spinning techniquethatallowstheproductionof bioinspiredsilkfiberswithapplicationsto thetherapyof tendonand ligamentinjuries

1. 1 www.upm.es
SFS: A new production technology for
high performance silk biomaterials
SFS is a novel spinning technique that allows the
production of bioinspired silk fibers with applications to
the therapy of tendon and ligament injuries
Universidad Politécnica de Madrid
Madrid, December 3rd 2014

2. 2 www.upm.es
Tendon and ligament injuries
Tendon and ligament injuries are highly disabling and require long
convalescence
26-3-2014
6 months off work
19-3-2014
8 months off work

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Business opportunity
Average total cost: 6000 €
Convalescence: 4-9 months
Surgical operations / year (Spain)
25000
9000
35000

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Present solutions
• Autograft • Polymeric ligament (Goretex)
?

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Proposed solution: SFS

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Proposed solution: Why SFS?
• Active regeneration
• Biocompatible
• Self stressing
• Environmentally friendly
• Controlled biodegradability

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SFS: Next steps
• Present situation: Laboratory prototype
• Phase 1: Completion of the product development (1 year)
• Patent application
• Pre-clinical trials in an animal model
• Construction of an industrial prototype
• Phase 2: Clinical trials (3 years)
• Search of a pharmaceutical partner

8. 8 www.upm.es
Business model
• Estimated prices of the end product:
• Anterior cruciate ligament: € 400 (6 % of total surgical costs )
• Achilles tendon: € 600 (10 % of total surgical costs)
• Rotator cuff: € 300 (5% of total surgical costs)

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Research team
• Laboratory of Biomaterials. Centro de Tecnología Biomédica UPM
José Pérez Rigueiro, Associate Professor
Gustavo V. Guinea Tortuero, Full Professor
• Laboratory of Fluid Physics and Microfluidics. US
Alfonso Miguel Gañán Calvo, Full Professor

10. 10 www.upm.es
Contact to:
José Pérez Rigueiro
Laboratorio de Biomateriales
Centro de Tecnología Biomédica
jperez@mater.upm.es
Universidad Politécnica de Madrid