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Malaria 2003
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4. Chloroquine resistant-PF Chloroquine sensitive-PF Malaria Endemic Areas Mexico, Central America west of Panama canal, Carribean, South America, middle east Resistant PV Indonesia,Papua New Guinea, Burma
14. Spor Liver RBC forms Class I P.E Hypno Asex Gam Chloroquine - - - + ( ±) Mefloquine - - - + - Quinine - - - + ( ±) Pyrimethamine+ Sulfadoxin - ± - + _ T.C - - - ± - Class II Atovaquone+Proguanil - [+] - + - Class III Primaquine - + + - +
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19. Life Cycle And Drugs NONE Pyrimethamine Proguanil Primaquine Most of the drugs Except Primaquine Chloroquine Quinine [not F.P.]
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43. G6PD Glucose Glucose-6-Phospate 6-Phoshogluconate Hexokinase NADP NADPH GSSG GSH Defeciency GSH DEF. Hemolysis No protection For RBC’s Against Oxidative substances Hemolysis
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56. Chemoprophylaxis Type Drug Before Entering After Leaving Chloroquine Sensitive Chloroquine po 4 500mg once a week 1-2weeks 4 weeks Resistant strains Pro+Ato(Malarone) 1tab/d 1-2 days 7 days Mefloquine 250mg/week 1-2 weeks 4 weeks Doxycycline 100mg 1Tab o.d. 1 day before 4 weeks
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62. Severe malaria Oral not possible Any species Non-Falciparum Falciparum P.Vivax Chlo Resistant F.P. Chlo Sensitive F.P. Chlo Resistant P.Vivax Chlo Sensitive Primaquine for Radical cure
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