This document lists various medical terms and conditions. It includes:
1. Names of medical conditions, anatomical structures, cell types, stains, and imaging findings.
2. Systems covered include dermatology, infectious diseases, hematology, cardiology, pulmonary, gastrointestinal, renal, neurology, and oncology.
3. Related information provided for some terms includes associated symptoms, cell or tissue affected, and relevant clinical information.
24. Osteoblasts Mature bone Osteoclasts Intramembranous
Bone
Endochondral Bone
(left to right)
Skeletal muscle
(I band-light, A band-
dark)
Cardiac muscle
(junctional complexes
and single nucleus)
Smooth muscle (gap
junctions and fusiform
fibers)
30. Manouvers
Increase
Preload
Right side Deep breath. (Inspiration)
Laying supine
Left side Expiration
Increase
Afterload
Aortic/Systemic Hand grip
Sustained squatting
Pulmonary NOT IMPORTANT
Valsalva Increases
thoracic
pressure
Reduces right sided
murmurs
Decreases Heart rate and
BP (Parasympathetic)
31. . A P . 2-3rd
5-6th
.
Aortic
Pulmonary
Tricuspid
Mitral
Close at beginning of S
Open at beginning of D
Close at beginning of D
Open at beginning of S
Sounds are generated at the time of closure.
S1 beginning of systole
S2 beginning of diastole
Stenosis – Anterograde Insufficiency – Retrograde
MT
A: Systolic – Aortic stenosis
P: Systolic – Mitral insufficiency
T: Systolic – Tricuspid insufficiency
T: Diastolic – Tricuspid stenosis
M: Diastolic – Mitral stenosis and aortic insufficiency
T
P
32.
33. Murmur
Systolic
Bicuspid aortic
valve
Early systolic
High-frequency
click
Right 2nd
interspace
Hypertrophic
Cardiomyopathy
Crescendo-
decrescendo
murmur
Between apex
and left sternal
Radiates to the
suprasternal
notch
Louder standing
up
Aortic Stenosis
Early Systolic
Click
Pulse late and
weak
Old age /
Rheumatic F.
Congenital
Bicuspid valve
Angina, syncope,
CHF
Pulmonary
Stenosis
Tetralogy of
Fallot
Harsh ejection
murmur
Systolic thrill
Mitral
Regurgitation
Holosystolic
Radiates to axilla
Increases After
load
Tricuspid
Regurgitation
Holosystolic
Increase right
heart Flow
Taking a Deep
breath
IV drug users w/
endocarditis
Septal Defects
Ventricular
Harsh
Holosystolic
Atrial
Fixed Splitting of
S2
Diastolic
Atrial
Regurgitation
Blowing murmur
Widened pulse
pressure
Pulmonary
Regurgitation
Mitral Stenosis
Opening snap
Rheumatic Fever
Tricuspid
Stenosis
35. a
c
x
v
y
A: Right atrial contraction
B: Bulging of tricuspid valve during right ventricular contraction
X: Right atrial relaxation
V: Continued inflow of venous blood
Y: Passive emptying of right atrium after tricuspid valve opening
Jugular Venous Tracing
43. Neural Tube
Prosencephalon
Telencephalon
Cerebral
hemispheres
(Cerebral cortex,
basal ganglia, deep
white matter)
Diencephalon
Thalamus
Motor and sensory
relay nuclei
Hypothalamus
Control of
endocrine and
autonomic function
Epithalamus
Pineal gland
Subthalamus
Component of basal
Ganglia
Posterior lobe of
the pituitary
Neural Retina
Mesencephalon Rhombencephalon
Metencephalon
Cerebellum
Pons
CN V, VI, VII, VIII
Myelencephalon
Medulla oblongata
CN VIII-XIII
45. Korsakoff syndrome
Amnesia, confabulation and
preserved long-term memory
Lesions in the anterior and medial
thalami
Wernicke Encephalopathy
Encephalopathy, ocular dysfunction
and ataxia
Atrophy of Mamillary bodies
Cerebellar Degeneration
Tremor, unsteady gait
Loss of Purkinje cells in the
cerebellar vermis
46. Upper Motor Neuron
Lesion
• Spastic Paresis
• Hyperreflexia
• Babinski sign
• Increased muscle tone
• Clasp knife reflex
• Disuse atrophy of
muscles
• Decreased speed of
voluntary movements
• Large area of the body
involved
Lower Motor Neuron
Lesion
• Flaccid paralysis
• Areflexia
• No Babinski
• Fasciculations
• Decreased muscle tone
or atonia
• Atrophy of muscle(s)
• Loss of voluntary
movements
• Small area of the body
affected
47. Foramen Rotundum- CN V2 (Maxillary Nerve)
CN V3 (Mandibular Nerve)Foramen Ovale-
Superior Orbital Fissure
CN II (Optic Nerve)
Ophthalmic Artery
CN III (Oculomotor Nerve)
CN IV (Trochlear Nerve)
CN V1 (Ophthalmic Nerve)
CN VI (Abduncens Nerve)
Ophthalmic Veins
Optic Canal
Cribiform Plate- CN I (Olfactory Nerve)
Foramen Spinosum
Foramen Lacerum-
Middle Meningeal A.
Meningeal N. (V3)
Internal Carotid Artery
48. Skull Foramen Traversing Structures
Anterior Cranial Fossa Cribiform plate CN I olfactory bundles
Middle Cranial Fossa Optic canal CN II, ophthalmic artery, central
retinal vein
Superior Orbital fissure CN III, IV, V1, VI, ophthalmic
vein, sympathetic fibers
Foramen rotundum CN V2 (maxillary)
Foramen ovale CN V3 (mandibular)
Foramen spinosum Middle meningeal artery and
vein
Posterior Cranial Fossa Internal acoustic meatus CN VII, VIII
Jugular foramen CN IX, X, XI, jugular vein
Hypoglossal canal CN XII
Foramen magnum Spinal roots of CN XI, brain
stem, vertebral arteries
49. Spinal Cord Hemisection
(Brown-Sequard Sx)
Ipsilateral
• Spastic Weakness
• Altered vibratory sense
Contralateral
• Loss of pain and temperature
NO Cranial Nerve signs
54. Parkinson Disease
Bradykinesia, cogwheel rigidity, resting tremor, shuffling gait,
Stooped posture, masked face, depression and dementia
Pathognomonic: Lewy bodies
Loss of dopaminergic neurons from substantia nigra
Huntington Disease
Chorea (rapid movements), athetosis (slow movements),
personality changes, dementia
Type of disease: Autosomal Dominant (Chromosome 4)
Degeneration of GABA neurons, causing atrophy of head
of caudate nucleus
Wilson Disease
Tremor, asterixis, parkinsonian symptoms, chorea, fatty change,
Neuropsychiatric symptoms, hepatitis or cirrhosis, tremor may
be “wing beating”.
Pathognomonic: Kayser-Fleischer ring
55. Hemiballism
CONTRALATERAL Wild, flinging movements of limbs
Pathognomonic: Hypertensive Patients
Hemorrhagic destruction of subthalamic nucleus
Tourette Syndrome
Motor and vocal tics, commonly associated with OCD and ADHD
Treatment: Antipsychotic agents
Excess of striatal dopamine
56. POLIO
Flaccid Paralysis, Muscle atrophy, Fasciculations, Areflexia
TABES DORSALIS
Paresthesias, Pain, Polyuria/Urine retention, Associated w/neurosyphilis,
+Romberg sign, suppressed reflexes, pupillary reflex defects.
ALS
Spastic paralysis in lower limbs, flaccid paralysis in upper limbs, increased
tone and reflexes.
ANTERIOR SPINAL ARTERY OCCLUSION
Pain, temperature and spastic weakness bilateral signs, spastic bladder
Vibratory and pressure senses spared
57. SUBACUTE COMBINED DEGENERATION
Paresthesias, bilateral spastic weakness, Babinski sign, antibodies
to the intrinsic factor (Vitamin B12 pernicious anemia)
SYRINGOMYELIA
Bilateral loss of pain and temperature upper limbs. “Cape-like”
It eventually gets to flaccid paralysis and atrophy of the upper limb
May be associated with hydrocephalus and Arnold Chiari II.
BROWN-SÉQUARD SYNDROME (HEMISECTION)
Ipsilateral Horner’s sx, paresis, loss of position and vibratory senses.
Contralateral loss of pain and temperature.
58. Hypothalamus
Anterior Region
Paraventricular and
Supraoptic Nuclei
Synthesize ADH and
Oxytocin
Suprachiasmatic
Nucleus
Circadian Rhythms
Tuberal Region
Arcuate Nucleus
Release hormones in
the anterior pituitary
Ventromedial Nucleus Satiety center
Posterior Region Mamillary Bodies Wernicke-Korsakoff
Hypotalamic Zone
Anterior
Senses elevation of
temperature
Posterior
Senses decrease of
temperature
Lateral Feeding center
Preoptic Area .
Sensitive to androgens
and estrogens
59. Expressive Aphasia- Agraphia, decreased ability to repeat words
or answer questions. Single-syllable words (pt frustrated)
Left MCA infarct
Lower face weakness if associated w/Primary motor cortex
Receptive Aphasia-Oral aphasia (they don’t understand) if restricted
to area 22. They use “word salad” to speak, paraphasic speech.
Aware and not concerned, fluent speech but incoherent.
May have hearing loss.
Gerstmann Syndrome- Alexia with agraphia, often seen with
acalculia, finger agnosia (particularly right hand).
60. Conductive Aphasia- Speech and comprehension may be normal,
but patient paraphrases and needs word-finding pauses.
Pt cannot repeat words or execute verbal commands.
Aware and frustrated. Cannot speak or write
Area 7, 39 ,40
Asomatognosia/Neglect- Unawareness or neglect of contralateral
Half of the body. Pt ignores left side of his body or things.
Visual Agnosia- Inability to recognize visual patterns or objects.
If lesions 20 and 21 involved pt develops prosopagnosia which is
the inability to recognize faces.
61. Transcortical Apraxia- From an occlusion of the ACA
Inability to move the left arm to respond to verbal commands
NO motor weakness.
Alexia without Agraphia- From an occlusion of the left PCA
Right homonymous hemianopsia w/macular sparing.
Visual information cannot reach the language area.
Color anomia, pt unable to read, able to write.
Kluver-Bucy Syndrome- Hypersexuality, hyperphagia and
visual agnosia.
62. Global Aphasia- Both Broca and Wernicke are damaged.
Includes labored telegraphic speech and poor comprehension.
NO motor weakness. Naming severely impaired
Transcortical Aphasia- Capacity to repeat statements unimpaired
Patient cannot speak spontaneously.
NO motor weakness.
63. 1. Parinaud’s Syndrome
2. Korsakoff’s psychosis
3. Contralateral leg weakness
4. Superior quadrantanopia w/macular sparing
5. Alexia without agraphia
6. Hoarseness
7. Difficulty chewing
8. Temperature regulation
9. Rathke’s pouch
10. Truncal ataxia
D
E
A
C
B
M
F
G
H
I
L
K
1. M- Pineal gland Tumor
2. L- Mamillary body degeneration
3. D- Motor homunculus (precentral gyrus)
4. B- Lingual Gyrus (Meyer’s Loop)
5. A- Splenium of Corpus Callosum lesion
6. H- Vagus nerve rostral medulla
7. G- Trigeminal nerve rostral pons
8. I- Hypothalamus
9. K-Anterior Pituitary gland
10. J- Posterior part of the cerebellar vermis
J
64. Autosomal Recessive Autosomal Dominant
Onset
Early uniform onset
(Infancy or childhood)
Variable onset (may be
delayed into adulthood)
Penetrance Complete Penetrance
Incomplete penetrance with
variable expression
Mutation Usually an enzyme protein
Usually a structural protein or
receptor
Requires Mutation of both alleles Mutation of one allele