6. Produces Two Hormones Called
• Thyroxine (T4)
• Thyronine (T3)
• Regulates Metabolism so Your Cells Function
Properly
Affects Every Cell in the Body
10. Diffuse Non-Toxic Goitre
Compensatory Hypertrophy & Hyperplasia due to
Decrease in T3 & T4.
Diffusely Involves Whole Gland.
Not Associated With
Hypo OR Hyperthyroidism.
11. Causes
Physiological Goitre:
Puberty OR Pregnancy.
Dietary Iodine Deficiency:
In Areas Far From Sea.
Dietary Goitrous Agents:
Cabbage & Turnips.
Calcium or Flouride in water.
PAS, Lithium, Phenylbutazone, Thiouracil, Carbimazol.
28. Key Points
Toxic Goitre are Rarely Malignant.
All Solitary Goitre Need to Exclude Malignancy.
Surgery is Rarely Needed in Autoimmune or
Inflammatory Thyroid Disease.