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Lecture 6. Transport/Circulation
Functions of the Circulatory System:
  –
      transport
  –
      defense
  –
      regulation
Animals without Circulatory System




        protozoans
                            sponges




 flatworms            cnidarians
•
    a single-celled protist living in water has a sufficient
    surface area of plasma membrane to service its entire
    volume
•
    the gastrovascular cavity of hydra opens to the
    exterior, both outer and inner layers of cells are
    bathed in water
•
    in cnidarians like Aurelia, the products of digestion in
    the gastrovascular cavity are directly available to the
    cells of the inner layer
•
    only a short distance to diffuse to the cells of the
    outer layer
•
    flat body = way to maximize exposure to the
    surrounding medium
– most organisms
  have extensively
  folded or
  branched internal
  surfaces specialized
  for exchange with
  the environment

– the circulatory
  system shuttles
  material among
  all the exchange
  surfaces within the
  animal
Internal Fluid Environment
• cellular cytoplasm in unicellular animals




            protozoans
Internal Fluid Environment
• multicellular animals
Two Types of Circulatory System


•
    Two types of circulatory systems
    •
        Closed – heart pumps blood in a network of
                 blood vessels and capillaries
    •
        Open – heart pumps haemolymph into
                tissue spaces
Two Types of Circulatory System




insects, other arthropods,         earthworms, squids,
most mollusks                      octopuses, vertebrates
Plan and Parts of Vertebrate Circulatory System

• often called the cardiovascular system
• the heart consists of one atrium or two atria, and
  one or two ventricles
• arteries, arterioles, veins, venules, and capillaries
• blood
Plan and Parts of Vertebrate Circulatory System


•
    The Vertebrate Circulatory System
    •
        Closed type
    •
        Heart :
        •
           Atrium – receive blood from circulation
        •
            Ventricle – pumps blood to blood vessels
Plan and Parts of Vertebrate Circulatory System


•
    The Vertebrate Circulatory System
    •
        Blood vessels :
        •
            Artery – brings blood AWAY from the heart
        •
            Arteriole – leads to capillaries
        •
            Capillary – where gas exchange takes place
        •
            Venule – leads to vein
        •
            Vein – brings blood TO the heart
– two-chambered heart

           – subsidiary chambers:
CA           sinus venosus (SV),
     Artery conus arteriosus (CA)

SV
           – blood circuit: single
             circuit
– three-chambered
              heart

            – blood circuit: double
              circuit
Vein   Artery
Heart of an Amphibian with Lungs
         Fig. 31.11
•
    Reptiles also have double
    circulation with
    pulmonary (lung) and
    systemic circuits

•
    reptilian heart is three-
    chambered (except for
    crocodiles)

•
    ventricle is partially
    divided
– four-chambered
                  heart
                – crocodilians, birds,
                  and mammals
                – blood circuit: double
                  circuit
Vein   Artery
Human Heart




                                  (Bicuspid or mitral valve)




(Tricuspid valve)
Coronary System
The Cardiac Cycle




Systole - contraction   Diastole - relaxation
•
    cardiac output (5.25 L/min) depends on two
    factors:

    –
        the rate of contraction or heart rate (number
        of beats per second)

    –
        stroke volume (75 mL), the amount of blood
        pumped by the left ventricle in each
        contraction
•
    the heart sounds we can hear with a stethoscope
    are caused by the closing of the valves

    –
        sound pattern is “lub-dup, lub-dup, lub-dup”

    –
        “lub” is created by the recoil of blood against
        the closed AV valves

    –
        “dup” is the recoil of blood against the
        semilunar valves
•
    the impulses generated during the heart cycle
    produce electrical currents that are conducted
    through body fluids to the skin


•
    the currents can be detected by electrodes and
    recorded as an electrocardiogram (ECG or
    EKG).
The control of heart rhythm
Fig. 31.14
–
    two sets of nerves (sympathetic and
    parasympathetic) affect heart rate with one
    set speeding up the pacemaker and the other
    set slowing it down
–
    the pacemaker is also influenced by
    hormones
–
    rate of impulse generation by the pacemaker
    increases in response to increases in body
    temperature and with exercise
The structure
of blood
vessels
32
     Blood flow in veins
The
interrelationship
of cross-
sectional area of
blood vessels,
blood flow
velocity, and
blood pressure.
Measurement of blood pressure




Makes use of a sphygmomanometer and the brachial artery
•



Systolic pressure - peak pressure in the arteries, which occurs near the end
•


of the cardiac cycle when the ventricles are contracting

Dyastolic pressure - minimum pressure in the arteries, which occurs near the
•


beginning of the cardiac cycle when the ventricles are filled with blood
Changes in blood pressure

Varies within the day due to circadian rhythm
•



Also change due to stress, nutrition, exercise,
•


drugs, disease, and simply standing up
Hypertension – when arterial pressure is abnormally
•


high
Hypotension – when arterial pressure is abnormally low
•
Blood flow in capillary
beds
Fluid exchange between capillaries and the interstitial fluid
The Blood
•
    Hemophilia – inability to clot blood
               – a sex-linked trait
      •
        Hemophilia A – clotting factor VIII deficiency
      •
        Hemophilia B – clotting factor IX deficiency

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Lecture 6 transport circulation_part 1

  • 1. Lecture 6. Transport/Circulation Functions of the Circulatory System: – transport – defense – regulation
  • 2. Animals without Circulatory System protozoans sponges flatworms cnidarians
  • 3. a single-celled protist living in water has a sufficient surface area of plasma membrane to service its entire volume • the gastrovascular cavity of hydra opens to the exterior, both outer and inner layers of cells are bathed in water
  • 4. in cnidarians like Aurelia, the products of digestion in the gastrovascular cavity are directly available to the cells of the inner layer • only a short distance to diffuse to the cells of the outer layer
  • 5. flat body = way to maximize exposure to the surrounding medium
  • 6. – most organisms have extensively folded or branched internal surfaces specialized for exchange with the environment – the circulatory system shuttles material among all the exchange surfaces within the animal
  • 7. Internal Fluid Environment • cellular cytoplasm in unicellular animals protozoans
  • 8. Internal Fluid Environment • multicellular animals
  • 9. Two Types of Circulatory System • Two types of circulatory systems • Closed – heart pumps blood in a network of blood vessels and capillaries • Open – heart pumps haemolymph into tissue spaces
  • 10. Two Types of Circulatory System insects, other arthropods, earthworms, squids, most mollusks octopuses, vertebrates
  • 11. Plan and Parts of Vertebrate Circulatory System • often called the cardiovascular system • the heart consists of one atrium or two atria, and one or two ventricles • arteries, arterioles, veins, venules, and capillaries • blood
  • 12. Plan and Parts of Vertebrate Circulatory System • The Vertebrate Circulatory System • Closed type • Heart : • Atrium – receive blood from circulation • Ventricle – pumps blood to blood vessels
  • 13. Plan and Parts of Vertebrate Circulatory System • The Vertebrate Circulatory System • Blood vessels : • Artery – brings blood AWAY from the heart • Arteriole – leads to capillaries • Capillary – where gas exchange takes place • Venule – leads to vein • Vein – brings blood TO the heart
  • 14.
  • 15. – two-chambered heart – subsidiary chambers: CA sinus venosus (SV), Artery conus arteriosus (CA) SV – blood circuit: single circuit
  • 16. – three-chambered heart – blood circuit: double circuit Vein Artery
  • 17. Heart of an Amphibian with Lungs Fig. 31.11
  • 18. Reptiles also have double circulation with pulmonary (lung) and systemic circuits • reptilian heart is three- chambered (except for crocodiles) • ventricle is partially divided
  • 19. – four-chambered heart – crocodilians, birds, and mammals – blood circuit: double circuit Vein Artery
  • 20. Human Heart (Bicuspid or mitral valve) (Tricuspid valve)
  • 22.
  • 23. The Cardiac Cycle Systole - contraction Diastole - relaxation
  • 24.
  • 25. cardiac output (5.25 L/min) depends on two factors: – the rate of contraction or heart rate (number of beats per second) – stroke volume (75 mL), the amount of blood pumped by the left ventricle in each contraction
  • 26. the heart sounds we can hear with a stethoscope are caused by the closing of the valves – sound pattern is “lub-dup, lub-dup, lub-dup” – “lub” is created by the recoil of blood against the closed AV valves – “dup” is the recoil of blood against the semilunar valves
  • 27. the impulses generated during the heart cycle produce electrical currents that are conducted through body fluids to the skin • the currents can be detected by electrodes and recorded as an electrocardiogram (ECG or EKG).
  • 28. The control of heart rhythm
  • 30. two sets of nerves (sympathetic and parasympathetic) affect heart rate with one set speeding up the pacemaker and the other set slowing it down – the pacemaker is also influenced by hormones – rate of impulse generation by the pacemaker increases in response to increases in body temperature and with exercise
  • 32. 32 Blood flow in veins
  • 33. The interrelationship of cross- sectional area of blood vessels, blood flow velocity, and blood pressure.
  • 34. Measurement of blood pressure Makes use of a sphygmomanometer and the brachial artery • Systolic pressure - peak pressure in the arteries, which occurs near the end • of the cardiac cycle when the ventricles are contracting Dyastolic pressure - minimum pressure in the arteries, which occurs near the • beginning of the cardiac cycle when the ventricles are filled with blood
  • 35. Changes in blood pressure Varies within the day due to circadian rhythm • Also change due to stress, nutrition, exercise, • drugs, disease, and simply standing up Hypertension – when arterial pressure is abnormally • high Hypotension – when arterial pressure is abnormally low •
  • 36. Blood flow in capillary beds
  • 37. Fluid exchange between capillaries and the interstitial fluid
  • 39.
  • 40. Hemophilia – inability to clot blood – a sex-linked trait • Hemophilia A – clotting factor VIII deficiency • Hemophilia B – clotting factor IX deficiency