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Presented By
JESNA BABY
1
Definition
It is defined as a mosquito borne
infectious disease of human caused by
parasitic protozon of the genus plasmodium
transmitted via a bite form an infected female
anopheles mosquito.
2
 By protozoan parasites of the genus protoz
plasmodium.
 4 species
 Plasmodium falciparum
 Plasmodium vivax
 Plasmodium ovale
 Plasmodium malariae
People get malaria by bittening of infected
female Anopheloes mosquito.
3
 An estimated 300 million cases of malaria
occur each year.
 Annually accounting for 1.5 to 2.7 million
death
 Most of the death are due to infection with
plasmodium falciparum & occur among
children & pregnant women in the developing
world , especially sub- Saharan Africa.
4
5
6
7
8
9
 Vector transmission – Bite by infective female
anopheles mosquitoes
 Direct transmission
 Blood transfusion
 The use of contaminated needle and syringe
 Organ transplant
 Congential transmission
 mother to new born
10
 Fever
 Shaking chills
 Headache
 Tiredness
 Nausea
 Vomiting
 Diarrhea
 It may cause anaemia and jaundice
11
 Environmental factor
 A warm humid climate temperature between
16℃ and 40℃ and abundant rainfall have
anopheles mosquitoes
 Vegetation nearby to provide shade for the
mosquito to hide the day and digest the
blood meal from the night before
12
 Human factor
 Poor water supply and sanitation
 People working in the field and in irrigation
system near or on lakes and reservoris
 Migrates moving into malarial areas clearing
land looking for work refuges
13
PREVENTION
 Preventing mosquito accessing egg laying habitats by
management& modification
 Coverivg ,emptying&cleaning of domestic water storage
containers
 apply insecticides to water storage outdoor containers
 Using personal household protection such as window
screen,long sleeved clothes,coils,vaporizers
 Massage exposed body parts with insect repellent,
 Spread awareness about dengue mosquito
 Prevent patient from being bitten by mosquitoes
 Breed small mosquito eating fishes in artificial pond to
eradicate mosquito larvae
 Blood film examination
o Thick blood film
Used for detecting malaria larger volume
of blood is examined allowing detection of
even low levels of parasitaemia.
17
 Thin blood film
o Gives more information about the parasite
morphology and therefore is used to identify
the particular infecting species of
plasmodium
18
 Rapid diagnostic tests
 PCR based techniques
 Fluorescent techniques
 Serologic tests
19
 Quinine
 Chloroquine
 Mefloquine
 Antibiotic (eg: doxocycline,
dindamycin,azithramycin)
20
21

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Malaria, its pathology, epidemiology and clinical manifestations

  • 2. Definition It is defined as a mosquito borne infectious disease of human caused by parasitic protozon of the genus plasmodium transmitted via a bite form an infected female anopheles mosquito. 2
  • 3.  By protozoan parasites of the genus protoz plasmodium.  4 species  Plasmodium falciparum  Plasmodium vivax  Plasmodium ovale  Plasmodium malariae People get malaria by bittening of infected female Anopheloes mosquito. 3
  • 4.  An estimated 300 million cases of malaria occur each year.  Annually accounting for 1.5 to 2.7 million death  Most of the death are due to infection with plasmodium falciparum & occur among children & pregnant women in the developing world , especially sub- Saharan Africa. 4
  • 5. 5
  • 6. 6
  • 7. 7
  • 8. 8
  • 9. 9
  • 10.  Vector transmission – Bite by infective female anopheles mosquitoes  Direct transmission  Blood transfusion  The use of contaminated needle and syringe  Organ transplant  Congential transmission  mother to new born 10
  • 11.  Fever  Shaking chills  Headache  Tiredness  Nausea  Vomiting  Diarrhea  It may cause anaemia and jaundice 11
  • 12.  Environmental factor  A warm humid climate temperature between 16℃ and 40℃ and abundant rainfall have anopheles mosquitoes  Vegetation nearby to provide shade for the mosquito to hide the day and digest the blood meal from the night before 12
  • 13.  Human factor  Poor water supply and sanitation  People working in the field and in irrigation system near or on lakes and reservoris  Migrates moving into malarial areas clearing land looking for work refuges 13
  • 14. PREVENTION  Preventing mosquito accessing egg laying habitats by management& modification  Coverivg ,emptying&cleaning of domestic water storage containers  apply insecticides to water storage outdoor containers
  • 15.  Using personal household protection such as window screen,long sleeved clothes,coils,vaporizers  Massage exposed body parts with insect repellent,  Spread awareness about dengue mosquito
  • 16.  Prevent patient from being bitten by mosquitoes  Breed small mosquito eating fishes in artificial pond to eradicate mosquito larvae
  • 17.  Blood film examination o Thick blood film Used for detecting malaria larger volume of blood is examined allowing detection of even low levels of parasitaemia. 17
  • 18.  Thin blood film o Gives more information about the parasite morphology and therefore is used to identify the particular infecting species of plasmodium 18
  • 19.  Rapid diagnostic tests  PCR based techniques  Fluorescent techniques  Serologic tests 19
  • 20.  Quinine  Chloroquine  Mefloquine  Antibiotic (eg: doxocycline, dindamycin,azithramycin) 20
  • 21. 21