Healthcare & Medical System/Service 1. Telemedicine/Telehealth Tele-monitoring Tele-counseling Tele-therapeutic 2. Precision/Personalized Medicine Precision Oncology Precision Therapeutics 3. Preventive Healthcare Infectious Diseases Forecasting Infectious Diseases Management 4. Clinical Trial & Practice Drug Discovery & Clinical Trial Clinical Practice Regenerative Medicine

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AI, Blockchain, IoT for Healthcare AT A Glance
Alex G. Lee1
Healthcare & Medical
System/Service
AI Bloclkchain IoT
Telemedicine/Telehealth
Tele-monitoring
Tele-counseling
AI analyzes vital signs monitoring
data of patients (e.g., heart rate, blood
pressure/glucose/oxygen, respiration
rate, ECG, EEG, temperature) with
chronic disease (e.g., COPD/asthma,
cancer, cardiovascular, diabetes,
mental health) to check health
conditions (e.g., exacerbation risk
prediction); AI analyzes physical
activities monitoring data of the
elderly/disabled people
(location/movement/environment,
steps walked, calories burnt, sleep
data) to identify situations for help
(e.g., fall detection using deep
learning)
Conversational agents/chatbots
provide answering of health queries
and health information (e.g.,
BioBERT for medical information
Privacy-preserving (e.g.,
zero-knowledge proofs)
data sharing; Privacy-
preserving AI analysis using
blockchain based
collaborative learning
Real-time data
collection from
medical monitoring
devices/wearable
devices/IoT sensors
for AI analysis
1
Alex G. Lee, Ph.D Esq., is a principal consultant at TechIPm, LLC.

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Tele-therapeutic
extraction); Automated
conversational interactions for
medication, nutrition, and exercise;
Conversational agents/chatbots
provide emotional support and mental
health tracking
Automated tele-diagnosis of clinical
conditions (e.g., deep learning
medical image diagnosis, predictive
diagnosis using disease progression
and variants in disease trajectories)
Precision/Personalized Medicine
Precision Oncology
AI analyzes proteomic profiling to
identify biomarkers; AI analyzes
biomarkers specific to a patient to
obtain explanations for patient-
specific predictions; AI analyzes
proteins to aid in diagnosis,
prognosis, and treatment of cancer;
AI classifies cancers using gene
expression data using stacked
autoencoders; Precision oncology
literature retrieval for gene mutation
similarities and treatment
Blockchain provides secure
genomic data sharing and
exchange platform;
Blockchain provides
privacy-preserving (off-
chain) storage for personal
health records ; Blockchain
provides ownership to
individual patient (e.g.,
control whom to give
permission to share data)
5G enabled big data
generation for
personalized medicine

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Precision Therapeutics
recommendation with respect to
patient information regarding the type
of tumor and its genetic composition
using a generative adversarial
network (e.g., medGAN)
AI relates specific proteins and assess
to signs of malignancy; AI classifies
individual disease risk and predicts
the susceptibility, occurrence,
recurrence, progression, survivability,
and phenotypes of a disease
as individualized to one’s genomics,
lifestyle, and other traits; Deep
leaning provides combined genetic
variants effects and predict complex
polygenic diseases; AI identifies
potential drug targets; Reinforcement
learning-based control of customized
drug dosing for pharmacogenomics &
cancer chemotherapy treatment
Blockchain provides
autonomous patient consent
for therapeutic trials using
smart contracts
Real-time continuous
data streams for
therapeutic trials

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Preventive Healthcare
Infectious Diseases Forecasting
Infectious Diseases Management
Infectious diseases (e.g., Coronal
virus, Ebola, Zika and other
Epidemics) risk/outbreak prediction
exploiting deep learning based
predictive analytics using disease
surveillance, demographic, weather,
environment, social media data; AI
analyzes vital signs monitoring data
of person (e.g., heart rate,
temperature) using wearable devices
for forecasting infection risk or
detecting early symptom of infection
AI analyzes activities/movements of
infected person/animal/object using
geo-location data and other sensing
data to identify potential infections
and trace infections/contact
Blockchain provides secure
data sharing and exchange
platform for AI analysis
Blockchain provides
privacy-preserving data
sharing for contact tracing;
Blockchain based incentive
system for encouraging
participation of social
distancing program
IoMT (Internet of
Medical Things)
system development
(e.g., contactless
automotive Medical
IoT system)
Bluetooth mesh and
GPS positioning
system network for
contact tracing (e.g.,
Covid-19)

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Clinical Trial & Practice
Drug Discovery & Clinical Trial
Clinical Practice
Regenerative Medicine
Molecular modeling in drug design
using deep learning (e.g., recursive
neural networks, autoencoders,
generative adversarial networks, and
reinforcement learning) ; AI analyzes
trial databases and social media to
identify potential matches between
clinical trials of relevance and
specific patients
Deep learning based Clinical
Decision Support System (CDSS)
using electronic health record (EHR)
and historical medical knowledge
base for diagnosis, therapy, treatment
and medical prescription; Deep
learning based computer-aided
diagnosis exploiting medical image
analysis (e.g., MedGAN for medical
image translation, SegAN for medical
image segmentation) & content based
image retrieval system;
Reinforcement learning to find
optimal medical prescriptions to
patients with various diseases
AI-guided Stem-Cell/Gene therapy;
AI supported brain-computer
interface; Anti-aging medicine
development
Blockchain provides
trustworthiness of clinical
trials by temper-proof end-
to-end
procedures/transactions
recording
Blockchain provides
privacy-preserving data
sharing for HER data;
Explainability for deep
learning (explainable AI
(XAI)) to improve trust on
decision made by AI
Real-time sensing data
for predictive
maintenance of
medical
devices/equipments;
Real-time therapy
monitoring system;
Sensing and uploading
up-to-date patient
information

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