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MENINGES, VENTRICLES, CEREBROS
 PINAL FLUID AND BOOLD SUPPLY
          OF THE BRAIN




      Dr. Israa M. Sulaiman
       Dr. Mohammed Faez
      Department of Anatomy
            IMS/MSU
OBJECTIVES

•    Illustrate and describe the Meninges’s three
     membranes.
• Describe the structure of the meninges, its
     blood supply and nerve supply.
• Illustrate and describe the venous blood
  sinuses
The Meninges
• The Meninges are the
  membrane covering the
  brain and spinal cord.
• The Meninges consist of
  three membranes:
1. The dura mater,
2. The arachnoid mater,
3. The pia mater.
The Meninges
The Meninges
1. Dura mater -             • 2. Arachnoid -
   strong, "Tough mother"     spidery, holds blood
   a. Falx cerebri            vessels
   b. Falx cerebelli
   c. Tentorium cerebelli   • 3. Pia mater -
   d. Diaphragma sella        "delicate mother"
The Meninges
1) Falx cerebri




                                         2) Tentorium
                                         cerebelli
4) Diaphragma sellae
                                           3) Falx
                                           cerebelli



Sagittal section showing the duramater
1) Falx cerebri
  2) Tentorium
  cerebelli




Superior view showing the duramater
DURA MATER
 Thick dense inelastic membrane
  and the outermost layer of the
  meninges
 Bilaminar:
        Endosteal layer (outer)
        Meningeal layer (inner)
  These are closely united except
  along certain lines, where they
  separate to form venous sinuses.
DURA MATER
 Endosteal layer ;
    o    Periosteum - inner surface of the
        skull bones
    o   Not continuous with dura mater
        of spinal cord
 Meningeal layer ;
    o Dura mater proper
    o Covering the brain
    o Continuous with dura mater of
      spinal cord
    o Folded inwards as 4 septa
      between part of the brain
    o The function of these septa is to
      restrict the rotatory displacement
      of the brain.
duramater

Superior
cerebral
veins
beneath
arachnoid
Superior sagittal sinus
                                                Dura mater
            (Dural venous sinus)

                                                  Endosteal layer


                                                  Meningeal layer


                                                They are closely
                                                united except along
                                                certain lines; they
                                                are separated to
                                                form venous
                                                sinuses
                          Subdural space




Coronal section of the upper part of the head
DURA MATER
Dura mater septa:
  1.   Falx cerebri
  2.   Falx cerebelli
  3.   Tentorium cerebelli
  4.   Diaphragma sella
1) Falx cerebri




                                         2) Tentorium
                                         cerebelli
4) Diaphragma sellae
                                           3) Falx
                                           cerebelli



Sagittal section showing the duramater
The Falx Cerebri
•   It is a sickle-shaped fold of dura
    mater that lies in the midline
    between the two cerebral
    hemispheres.
•   Its narrow end in front is attached to
    the internal frontal crest and the
    crista galli.
•   Its broad posterior part blends in the
    midline with the upper surface of the
    tentorium cerebelli.
•   The superior sagittal sinus runs in its
    upper fixed margin, the inferior
    sagittal sinus runs in its lower
    concave free margin, and the straight
    sinus runs along its attachment to the
    tentorium cerebelli.
Superior sagittal sinus          Falx cerebri



                                                                    Tentorium
                                                                    cerebelli
Frontal crest




Crista galli
                            *



               Inferior
               sagittal sinus                         Straight
                                                      sinus
The Tentorium Cerebelli
• The tentorium cerebelli
  is a crescent-shaped
  fold of dura mater that
  roofs over the posterior
  cranial fossa.
• It covers the upper
  surface of the
  cerebellum and
  supports the occipital
  lobes of the cerebral
  hemispheres.
Tentorium
cerebelli



 Falx cerebri
The Falx Cerebelli
• The falx cerebelli is a
  small, sickle-shaped fold of
  dura mater that is attached
  to the internal occipital
  crest and projects forward
  between the two cerebellar
  hemispheres.
• Its posterior fixed margin
  contains the occipital sinus.
The Diaphragma Sellae
• The diaphragma sellae
  is a small circular fold of
  dura mater that forms
  the roof for the sella
  turcica.
• A small opening in its
  center allows passage
  of the stalk of the
  pituitary gland
Dural Nerve Supply
• Branches of the trigeminal, vagus, and first
  three cervical nerves and branches from the
  sympathetic system pass to the dura.
• The dura is sensitive to stretching, which
  produces the sensation of headache.
Dural Blood Supply
Dural Arterial Supply             Dural Venous Drainage
• The dura mater’s arteries       • The meningeal veins lie in
  supply from the internal          the endosteal layer of dura.
  carotid, maxillary, ascending   • The middle meningeal vein
  pharyngeal, occipital, and        follows the branches of the
  vertebral arteries.               middle meningeal artery
• From a clinical                   and drains into the
  standpoint, the most              pterygoid venous plexus or
  important is the middle           the sphenoparietal sinus.
  meningeal artery, which is      • The veins lie lateral to the
  commonly damaged in head          arteries.
  injuries.
Arachnoid Mater
 Delicate, impermeable &
  avascular membrane covering the
  brain
 Lying between Pia mater
  (internally) & dura
  Mater(externally)
 Separated from dura mater by a
  potential space, the subdural
  space (filled by a film of fluid)
 Separated from pia mater by the
  subarachnoid space (filled with
  CSF)
 The outer and inner surfaces
  covered with flattened
  mesothelial cells
Superior
cerebral
veins
beneath
arachnoid


Arachnoid mater
Arachnoid mater
                                  Arachnoid projects into venous
                                  sinuses
                                  - sites for CSF diffuses into
                                  bloodstream




Arachnoid
granulations

      Arachnoid mater                     Arachnoid villi

      Subarachnoid space     Subdural space
SUBDURAL SPACE :

• Superior cerebral         Superior cerebral veins
                            beneath arachnoid
  veins, traverse the
  subdural space to reach
  the superior sagittal
  sinus and its lacunae
*
    Dura




    Arachnoid




                Subdural haematoma
Subarachnoid Space (SP) :
 Relatively narrow over the surface of cerebral
  hemisphere, but sometimes becomes much wider in
  areas at the base of the brain, the widest space is
  called subarachnoid cisterns
 The cisterna cerebellomedularis lies between inferior
  surface of the cerebellum and roof of 4th ventricle
 The cisterna interpeduncularis lies between 2 cerebral
  hemispheres. All the cisternae are in free
  communication with one another & with the
  remainder of subarachnoid space
Superior
                                                               cistern




Chiasmatic
cistern

      Interpeduncular
     cistern
                   Pontine                         Cerebellomedullary cistern
                   cistern

        Median sagittal section to show the subarachnoid cisterns &
        circulation of CSF
Pia mater

    Arachnoid




    Dura




*

                Subarachnoid haemorrage
Pia Mater
• Pia Mater is a vascular
  membrane covered by
  mesothelial cells.

• Closely invests the
  brain, covering the
  gyri, descending into
  the deepest sulci &
  closely applied to the
  cortical surface.
Pia mater




            Pia mater
Pia Mater
 It extends out over the cranial nerves & fuses
  with their epineurium
 The cerebral arteries entering the substance of
  the brain, carry a sheath of pia mater with them
 The pia mater forms the TELA CHOROIDAE .
 The tela choroidae fuse with ependyma to form
  the choroid plexus
 Choroid plexus forms CSF
Choroid plexus of
lateral ventricle


          Ependyma
        Pia mater of
        tela choroidae

              Choroid plexus
              of 3rd ventricle



   Coronal section of the interventricular foramen showing the choroid
   plexus of 3rd & lateral ventricles
Read About

The Venous Blood Sinuses
VENTRICLES
OBJECTIVES

•   Illustrate and describe the ventricles.
•   Describe the structure of the ventricles.
•   Illustrate and describe the cerebrospinal
    fluid (CSF) formation, absorption and
    circulation.
VENTRICLES(Ventricular System)
• A ventricle is an internal
  cavity of the brain. Within
  the brain, which is filled
  with cerebrospinal
  fluid(CSF).
• The ventricular system is
  composed of two lateral
  ventricles and two midline
  ventricles( third and fourth
  ventricles).
VENTRICLES(Ventricular System)
• The chambers are
  connected to allow the flow
  of cerebrospinal fluid via
  two interventricular
  foramen (referred to as the
  foramen of Monro) and the
  cerebral aqueduct (referred
  to as the aqueduct of
  Sylvius).
Lateral ventricle

Interventricular
foramen (Monro)

                                                            Cerebral
                                                            aqueduct

                                                         Fourth ventricle
    Third ventricle

                                                         Central canal of
                                                         medulla
                                                         oblongata &
                                                         spinal cord

Lateral view to show the ventricular system of the CNS
VENTRICLES(Ventricular System)
CONSISTS OF :
  1) Lateral ventricle
  2) Third ventricle
  3) Fourth ventricle
  4) Central canal of the
     medulla oblongata
     & spinal cord
42
43
Lateral Ventricles
• The lateral ventricles
  are two curved shaped
  cavities located within
  the cerebrum.
• The lateral ventricles
  are separated by the
  septum pellucidum and
  do not communicate
  directly
Lateral ventricle

                          Parietal lobe




Frontal lobe
                                          Occipital lobe



               Temporal lobe
Lateral ventricle
 C-shaped cavity & may be divided into :



                              1. Body


            2. Anterior
                                                        3. Posterior
            horn           Third
                                                        horn
                           ventricle


                              4. Inferior
                              horn
                                            Fourth
                                            ventricle

        Lateral view of the ventricular cavities of the brain
Posterior horn
    Anterior horn




                    Inferior horn


Lateral view to show the ventricular system of the CNS
Third ventricle
 The third ventricle is a narrow cavity or a slitlike cleft between the 2
thalamus
 Communicates ;
         • Anteriorly with lateral ventricles through interventricular foramina
         (of monro)
         • Posteriorly with fourth ventricle through cerebral aqueduct (of
         sylvius)




         Posterior view to show the ventricular system of the CNS
Third ventricle

                          Parietal lobe




Frontal lobe
                                          Occipital lobe



               Temporal lobe
Third ventricle


                              ROOF
                                                 Body of fornix


                                                            Lateral wall

                                                               Thalamus



Third
ventricle
                               FLOOR

                         Hypothalamus

            Coronal section of the brain (posterior view)
Fourth ventricle
• The fourth ventricle Is a
  rhomboid or diamond
  shaped cavity.
• It is a wide and
  flattened space located
  just anterior to the
  cerebellum and
  posterior to the
  upper, or superior, half
  of the medulla
  oblongata and the pons.
Fourth ventricle


                                                    Fourth
                                                    ventricle
 Cerebral
 aqueduct
                                                                 POSTERIOR
ANTERIOR
                                                                 Cerebellum

  Pons

Medulla
oblongata
(superior
half)                                                           Central
                                                                canal
                                                                (spinal
            Sagittal section of the 4th ventricle               cord)
Fourth ventricle

                          Parietal lobe




Frontal lobe
                                          Occipital lobe



               Temporal lobe
Roof or posterior wall of fourth
ventricle :
                                                  Superior part of the roof ;
                                                        Superior medullary velum


     Cerebral
     aqueduct

   ANTERIOR

                                                                        POSTERIOR
      Pons

   Medulla
   oblongata
   (superior
   half)
                                               Inferior part of the roof ;
                                                     Inferior medullary velum
Fig. : Sagittal section of the 4th ventricle
Floor or rhomboid fossa of fourth ventricle :
                                                  Medial
                                                  sulcus
Formed by ;                                       (divides the floor
                                                  into symmetrical
                                                  halves)
 1. Posterior
 surface of the
 pons                                                       Medial
                                                            eminence

  2. Cranial ½
                                                             Sulcus
  of the
                                                             limitans
  medulla
  oblongata
                                                         Facial
                                                         colliculus

                                                   Stria
Posterior view of the                              medullaris
4th ventricle           Vagal      Hypoglossal    (strands of nerve
                        triangle   triangle       fibers)
CENTRAL CANAL

 Opens superiorly into the fourth ventricle



  Fourth
  ventricle

Extends ;
 Inferior ½ of
 medulla
 oblongata

                                                 Central canal
       Entire                                  (Lined with
       length of                               ependyma but no
       spinal cord                             choroid plexus in the
                                               central canal)
CENTRAL CANAL


                          Parietal lobe




Frontal lobe
                                          Occipital lobe



               Temporal lobe
Conus medullaris-
Terminal ventricle
CEREBROSPINAL FLUID
CHOROID PLEXUS
• It is formed by invaginating
  of vascular pia mater into the        Lateral ventricle

  ventricular cavity
• It becomes highly convoluted
  & produce a spongy-like
  appearance
• It enters the 3rd and 4th
  ventricles through their
  roofs, and the lateral
  ventricles through the
  choroid fissure                  Third ventricle
• produces cerebrospinal fluid
                                                            Fourth
  (CSF)                                                     ventricle
Pia Mater              Choroid
                      BODY OF                                                 Plexus of
   Cavity Of          FORNIX                                                  The Lateral
   Lateral                                                                    Ventricle
   Ventricle

                                        CORPUS
                                        CALLOSUM
                                                                      CN

                                                                            Pia Mater of
Ependyma                                                                    Tela
                                                      THALAMUS              Choroidae

 Cavity Of                                                                  Choroid
 Third                                                                      Plexus of
 Ventricle                                                                  The Third
                                                                            Ventricle


       Blood supply derives from choroidal branches of the internal carotid & basilar
                                         arteries
       Coronal section of the cavities of the lateral and 3rd ventricles
Arachnoid mater

                                                                 Pia mater

                                                                      Ependyma

                                                          Cavity of fourth ventricle
 CEREBELLUM
                                                                 Choroid plexus of the
                                                                 fourth ventricle




•T shaped, vertical part is double
• Horizontal part extends into lateral recesses of each ventricle (foramina of Luskha)
• Blood supply ; posterior inferior cerebellar arteries
What is cerebrospinal fluid (CSF) ?
•   Clear, colorless fluid
•   Produced by the choroid plexus
•   Found in the :
              Ventricles of the brain
             Subarachnoid space (between Arachnoid + Pia mater) around the brain
              & spinal cord


• The pressure of the CSF is kept remarkably constant.
• Based on the Monro-Kellie doctrine :
• “Volume of BLOOD, CSF & BRAIN at any time must be
  relatively constant”
Physical characteristics and composition of
                  the CSF
Appearance          Clear and colourless
Volume              130 ml
Rate of production 0.5 ml/min
Pressure            60-150 mm of water
Composition
 protein            15-45 mg/100 ml
 glucose            50-85 mg/ 100 ml
 chloride           720-750 mg/100 ml
No. of cells        0-3 lymphocytes/cu mm
Function of the CSF :
1. Cushions & protects the CNS from trauma
2. Provides mechanical buoyancy & support for the brain
3. Serves as a reservoir & assists in the regulation of the
   contents of the skull
4. Nourishes the CNS
5. Removes metabolites from the CNS
6. Serves as a pathway for pineal secretions to reach the
   pituitary gland
Sites of formation :
  1. Choroid plexus of the ventricle cavities, mostly is formed
     in the LATERAL VENTRICLES
  2. Some originate from the ependymal cells lining the
     ventricles
  3. Some from the brain substances through perivascular
     spaces

 Movement of CSF inside the ventricle is controlled
   by the:
    1. Pulsation of the artery in the choroid plexus
    2. By the aid of the cilia & microvilli of the ependymal
       cells
5

   Superiorly =
   lateral aspect of                          Choroid plexus of
   each cerebral                  1           the lateral ventricle
   hemisphere                2



                            3
Choroid plexus of                     3.2
the 3rd ventricle
                            3.1             Choroid plexus of
                                            the 4th ventricle
     Inferiorly =
     subarachnoid       4
     space around the
     brain & spinal
     cord
cerebrospinal fluid (CSF)
•   The CSF is formed in the lateral
    ventricles escapes by the foramen of
    monro into the third ventricle
•   From the third ventricle by the
    aqueduct into the fourth ventricle.
•   Then from the fourth ventricle the
    fluid is poured into the subarachnoid
    spaces through the medial foramen
    of majendie and the two lateral
    foramina of luschka.
•   There is no evidence that functional
    communications between the
    cerebral ventricles and the
    subarachnoid spaces exist in any
    region except from the fourth
    ventricle.
Site of formation
                                       Choroid plexus of the
                                       lateral ventricle
                                      1. Lateral ventricle
Superiorly                Interventricular foramina                                     Superiorly

                                      2. Third ventricle
                                      Cerebral aqueduct                      Absorbed
             Absorbed
                                      3. Fourth ventricle



                        3.2 Lateral                            3.2 Lateral
                        foramina                               foramina
                        (Luschka)                              (Luschka)
                                           3.1 Median
                                           foramen
                                           (Magendie)

                                      4. Subarachnoid space


                                            Inferiorly
Circulation of CSF in subarachnoid space :
                                                               Superior
                                                               cistern




Chiasmatic
cistern
                                                                 Median
      Interpeduncular                                            foramen of
     cistern                                                     4th ventricle

                   Pontine                         Cerebellomedullary cistern
                   cistern

        Median sagittal section to show the subarachnoid cisterns &
        circulation of CSF
Factors that facilitate the flow of CSF in
           subarachnoid space ;

 1. Pulsation of the cerebral & spinal arteries
 2. Movements of the vertebral column
 3. Respiration & coughing
 4. Changing of the positions
Absorption of CSF into dural venous sinuses

• Main sites - arachnoid villi
  (project into dural venous
  sinuses, especially, superior
  sagittal sinus)
• Arachnoid villi are covered by
  endothelium of the venous
  sinus
• Arachnoid villi tend to be
  grouped together & form
  elevations known as arachnoid
  granulations
• CSF pressure >> the pressure
  in the sinus
• The rate of absorption of CSF
  through the arachnoid villi
  controls the CSF pressure
CLINICAL APPLICATION
Hydrocephalus
• The term hydrocephalus is
  derived from the Greek
  words "hydro" meaning
  water and "cephalus"
  meaning head.
• It is excessive accumulation
  of fluid in the brain.
BLOOD SUPPLY OF THE BRAIN
OBJECTIVES

•       Illustrate and describe the formation of the
        circle of willis
•       Describe the blood supply of the brain
    –     Arterial supply
    –     Venous drainage
Blood Supply of The Brain
• The brain receives it
  arterial supply from two
  pairs of vessels, the
  vertebral and internal
  carotid arteries which
  are interconnected in
  the cranial cavity to
  produce an arterial
  circle (of Willis).
Internal carotid artery
Internal Carotid Artery
•   Begins – bifurcation of Com Carotid A
•   Perforates base of skull – carotid canal
•   Enters middle cranial fossa beside dorsum sellae
•   In the cavernous sinus
    – Horizontal
• Emerge out – medial side of Ant clinoid process –
  perforates dura & arachnoid mater – enters
  subarachnoid space
• Turns posteriorly – below optic nerve
• Turns upward – lateral to optic chiasma
• Now is under anterior perforated susbtance
• Divides – into ANTERIOR & MIDDLE cerebral arteries
Middle cerebral
        Posterior       artery
                                          Anterior cerebral
        communicating
                                          artery
        artery

                                          Internal carotid artery
                                          in cavernous sinus
Posterior cerebral
artery
                                                Internal carotid artery
Basilar artery                                  In temporal bone




                                          External carotid artery




 Vertebral artery

                                                Common carotid artery
Vertebral Artery
• Branch of first part of subclavian A
• Passes – foramen transvesarium C6 – C1
• Enters through foramen magnum – perforates
  dura & arachnoid mater – enters subarachnoid
  space
• Turns upward, forward, medially – medulla
  oblongata
• Lower border of pons – joins opposite side
  – BASILAR artery
Middle cerebral
        Posterior       artery
                                          Anterior cerebral
        communicating
                                          artery
        artery

                                          Internal carotid artery
                                          in cavernous sinus
Posterior cerebral
artery
                                                Internal carotid artery
Basilar artery                                  In temporal bone




                                          External carotid artery




 Vertebral artery

                                                Common carotid artery
Blood Supply of The Brain
• VERTEBRAL                     • INTERNAL CAROTID
  – Basilar                       – Middle cerebral
  – Posterior cerebral artery     – Anterior cerebral
                                  – Anterior communicating
                                    artery
                                  – Posterior
                                    communicating artery




                     CIRCLE OF WILLIS
Branches of :-

• VERTEBRAL                • INTERNAL CAROTID
  –   Basilar                –   ACA
  –   PCA                    –   MCA
  –   Pontine                –   Ophthalmic
  –   Labyrinthine           –   Ant ComA
  –   Ant Inf CA             –   Post Com A
  –   Sup cerebellar         –   Choroidal
  –   Choroidal
• CEREBRAL (ICA)              • CRANIAL (VERT)
   –   Ophthalmic                –   Meningeal
   –   Post Communicating        –   Post Spinal
   –   Choroidal                 –   Ant Spinal
   –   Ant Cerebral              –   Post Inf Cerebellar
        • Cortical               –   Medullary
        • Central
                              • (BASILAR)
        • Communicates with
            – Ant Comm Art
                                 –   Pontine
            – Post Cerebral      –   Labyrinthine
   – Mid Cerebral                –   Ant Inf Cerebellar
        • Cortical               –   Sup Cerebellar
        • Central                –   Post Cerebral
                                      • Cortical
                                      • Central
                                      • Choroidal
Circle of Willis
• Interpeduncular fossa –
  base of brain
• Anastomosis
   – 2 internal carotid
     arteries
   – 2 vertebral arteries
• In the subarachnoid
  space
INFERIOR VIEW
Anterior
     communicating                             Anterior cerebral
      artery                                   artery


                              Internal                             Middle cerebral
                              carotid                              artery
                              artery
Posterior
communicating
 artery
                                                      Sup cerebellar A
    Posterior cerebral
    artery                               Basilar A

                                                      Ant Inf cerebellar A



                                                       Post Inf cerebellar A


                         Vertebral arteries
Anterior cerebral artery



                            Middle cerebral artery




Posterior cerebral artery
Central sulcus
    Superior
    parietal                                  Superior frontal gyrus
    lobule




                                               Frontal pole
Parieto-
occipital
sulcus




                               Frontal pole



    Anterior cerebral artery
ANTERIOR CEREBRAL ARTERY
LOBE        AREA

FRONTAL     Motor – lower limb and perineum -
LOBE        pericentral lobule

PARIETAL    Sensory – lower limb and perineum -
LOBE        paracentral lobule
Anterior cerebral artery & anterior communicating artery




Lentiform nucleus
                                    lentiform

Caudate nucleus                                            Internal
                                                           capsule


Internal capsule                     caudate

(ANT)

Hypothalamus (ANT)
Temporal pole




Middle cerebral artery


  Central branches
Central branches




Lateral
striate
arteries




      Medial
      striate    Left middle          Right middle
      arteries   cerebral artery      cerebral artery
MIDDLE CEREBRAL ARTERY
LOBE        AREA

FRONTAL     Motor – except for paracentral lobule

            Motor speech – esp left side

PARIETAL    Sensory – except for paracentral lobule

            Sensory speech

TEMPORAL    Auditory
Middle cerebral artery & anterior choroidal artery




Lentiform nucleus
                                     lentiform

                                                     Internal
Caudate nucleus                                      capsule


                                     caudate
Internal capsule (ANT
& POST)
Inferior temporal gyrus




Posterior cerebral artery
                            Inferior temporal gyrus
POSTERIOR CEREBRAL ARTERY
LOBE        AREA

OCCIPITAL   Visual

TEMPORAL    Olfactory
Posterior cerebral artery & posterior communicating artery




Hypothalamus

Thalamus (ANT)                                                           Internal
                                                                         capsule

                                                                        thalamus
Cerebral peduncle


                                                             Cerebral
                                                             peduncle
Posterior lateral arteries




Thalamus (POST)

Geniculate bodies                                    thalamus



Cerebral peduncle
                             Lateral
                             Geniculate
                             bodies

                                          Cerebral
                                          peduncle
ARTERIES to specific brain areas
Corpus striatum    Middle & lateral    Anterior &
                   striate             Middle cerebral
Internal capsule                       artery
Thalamus           PComA, basilar, PCA
Midbrain           PCA, supCerebellarA, basilar
Pons               Basilar, Ant, inf, supCerebellarA,
Medulla            Vertebral, ASA,PSA,PICA, basilar
oblongata
Cerebellum         supCerebellar, AICA,PICA
VENOUS DRAINAGE of THE BRAIN

• EXTERNAL        • INTERNAL      • SPECIFIC
  – Superior        – Thalamo       – Midbrain
                                    – Pons
    cerebral        striate         – Medulla
  – Superficial                       oblongata
    middle          – choroidal     – cerebellum
    cerebral
  – Deep middle
    cerebral
Superior cerebral
Superior
Sagittal
sinus




                                   Superior
             Superficial           Sagittal
                                   sinus       Internal
             Middle
                                               cerebral
             cerebral
Transverse                                            Great
sinus                                                 cerebral
                                                          Straight
                                                          sinus
               Inferior
               Sagittal
               sinus                                    Occipital
                                                        sinus
                                              basal
Superior         Superior anastomotic V          Superior cerebral
        Sagittal
        sinus




Inferior anastomotic V




                                                  Superficial
                                                  Middle cerebral

      Transverse
      sinus
Superior
Sagittal   Inferior
sinus      Sagittal
           sinus
                       Internal
                       cerebral
                           Great
                           cerebral
                                  Straight
                                  sinus

                                  Site of
                                  junction
                                  with
                                  transverse
                                  sinus


                        Occipital
                        sinus
               basal
EXTERNAL CEREBRAL VEIN
VEIN          AREA                  DRAINS INTO

Superior                            Superior sagittal
cerebral      Lateral surface of    sinus
Superficial   cerebral              Cavernous sinus
middle        hemisphere
cerebral
Deep middle   Insula                Joined by ant
cerebral                            cerebral & striate-
                                    basal vein
Sup anas V    Superior sagittal sinus

Inf anas V    Inferior sagittal sinus
INTERNAL CEREBRAL VEIN
VEIN           AREA               DRAINS INTO

Thalamostriate Basal ganglia,     Internal cerebral
               thalamus,          vein - great
Choroidal      internal           cerebral vein –
               capsule,Tela       straight sinus
               choroidae of 3rd
               ventricle,hippo    DURAL VENOUS
               campus                SINUS
VEIN of specific areas

Midbrain            Basal, great cerebral


Pons                Basal, cerebellar


Medulla oblongata   Anterior & posterior spinal


Cerebellum          Great cerebral
Great
                                   cerebral
 Superior cerebral vein            vein

  Superior sagittal sinus          Straight
                                   sinus

                                                    Inferior sagittal sinus
  Middle cerebral vein
                                                           Medial aspect of
                                    Confluence of
                                                           hemisphere
  Cavernous sinus                       sinus

                    Superior
Inferior            petrosal
petrosal            sinus
sinus                          Transverse sinus
                                    (R   &    L)

               IntJugular                               IntJugular
               vein                                     vein

                                   Sigmoid sinus
                                   (R & L)
Inferior sagittal          Superior sagittal sinus            Falx cerebri
sinus


                                                                 Tentorium
                                                                 cerebelli

                                                                   Superior
                                                                   petrosal
                                                                   sinus



                           *
                                                                   Confluence of
                                                                   sinus

                                                                   Straight
                Inferior                                           sinus
                                 Sigmoid         Transverse
                petrosal
                                 sinus           sinus
                sinus
Cavernous sinus
Superior
petrosal
sinus

Inferior
petrosal
sinus                                                        Jugular
                                                             foramen

                                                            Sigmoid
                                                            sinus
           Straight
           sinus                                            Transverse
                                                            sinus
               Superiorsa
               gittal sinus                 Confluence of
                                            sinus
Cavernous sinus
• Lateral to body of sphenoid bone
• Connected to opposite – intercavernous S
• Receives blood
   – Middle cerebral V
• Drains into
   – Int Jugular V –via Inf petrosal sinus
   – Transverse S – via Sup petrosal S


• Dural Venous sinuses – emissary veins – extracranial V
CLINICAL APPLICATION
• Stroke or cerebrovascular accident:-
  – Blockage in the artery – cerebral infarction
     • Carotid artery
     • Basilar artery
  – Bleeding within the brain – intracerebral
    haemorrhage
     • Aneurysm
     • Subarachnoid haemorrhage
     • Intracerebral haemorrhage - hypertension
  – Damages one side of the body - contralateral
CVA – due to blockage
CVA – due to haemorrhage
THANK YOU

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Anatomy of meninges, ventricles, cerebrospinal fluid

  • 1. MENINGES, VENTRICLES, CEREBROS PINAL FLUID AND BOOLD SUPPLY OF THE BRAIN Dr. Israa M. Sulaiman Dr. Mohammed Faez Department of Anatomy IMS/MSU
  • 2. OBJECTIVES • Illustrate and describe the Meninges’s three membranes. • Describe the structure of the meninges, its blood supply and nerve supply. • Illustrate and describe the venous blood sinuses
  • 3. The Meninges • The Meninges are the membrane covering the brain and spinal cord. • The Meninges consist of three membranes: 1. The dura mater, 2. The arachnoid mater, 3. The pia mater.
  • 5. The Meninges 1. Dura mater - • 2. Arachnoid - strong, "Tough mother" spidery, holds blood a. Falx cerebri vessels b. Falx cerebelli c. Tentorium cerebelli • 3. Pia mater - d. Diaphragma sella "delicate mother"
  • 7. 1) Falx cerebri 2) Tentorium cerebelli 4) Diaphragma sellae 3) Falx cerebelli Sagittal section showing the duramater
  • 8. 1) Falx cerebri 2) Tentorium cerebelli Superior view showing the duramater
  • 9. DURA MATER  Thick dense inelastic membrane and the outermost layer of the meninges  Bilaminar:  Endosteal layer (outer)  Meningeal layer (inner) These are closely united except along certain lines, where they separate to form venous sinuses.
  • 10. DURA MATER  Endosteal layer ; o Periosteum - inner surface of the skull bones o Not continuous with dura mater of spinal cord  Meningeal layer ; o Dura mater proper o Covering the brain o Continuous with dura mater of spinal cord o Folded inwards as 4 septa between part of the brain o The function of these septa is to restrict the rotatory displacement of the brain.
  • 12. Superior sagittal sinus Dura mater (Dural venous sinus) Endosteal layer Meningeal layer They are closely united except along certain lines; they are separated to form venous sinuses Subdural space Coronal section of the upper part of the head
  • 13. DURA MATER Dura mater septa: 1. Falx cerebri 2. Falx cerebelli 3. Tentorium cerebelli 4. Diaphragma sella
  • 14. 1) Falx cerebri 2) Tentorium cerebelli 4) Diaphragma sellae 3) Falx cerebelli Sagittal section showing the duramater
  • 15. The Falx Cerebri • It is a sickle-shaped fold of dura mater that lies in the midline between the two cerebral hemispheres. • Its narrow end in front is attached to the internal frontal crest and the crista galli. • Its broad posterior part blends in the midline with the upper surface of the tentorium cerebelli. • The superior sagittal sinus runs in its upper fixed margin, the inferior sagittal sinus runs in its lower concave free margin, and the straight sinus runs along its attachment to the tentorium cerebelli.
  • 16. Superior sagittal sinus Falx cerebri Tentorium cerebelli Frontal crest Crista galli * Inferior sagittal sinus Straight sinus
  • 17. The Tentorium Cerebelli • The tentorium cerebelli is a crescent-shaped fold of dura mater that roofs over the posterior cranial fossa. • It covers the upper surface of the cerebellum and supports the occipital lobes of the cerebral hemispheres.
  • 19. The Falx Cerebelli • The falx cerebelli is a small, sickle-shaped fold of dura mater that is attached to the internal occipital crest and projects forward between the two cerebellar hemispheres. • Its posterior fixed margin contains the occipital sinus.
  • 20. The Diaphragma Sellae • The diaphragma sellae is a small circular fold of dura mater that forms the roof for the sella turcica. • A small opening in its center allows passage of the stalk of the pituitary gland
  • 21. Dural Nerve Supply • Branches of the trigeminal, vagus, and first three cervical nerves and branches from the sympathetic system pass to the dura. • The dura is sensitive to stretching, which produces the sensation of headache.
  • 22. Dural Blood Supply Dural Arterial Supply Dural Venous Drainage • The dura mater’s arteries • The meningeal veins lie in supply from the internal the endosteal layer of dura. carotid, maxillary, ascending • The middle meningeal vein pharyngeal, occipital, and follows the branches of the vertebral arteries. middle meningeal artery • From a clinical and drains into the standpoint, the most pterygoid venous plexus or important is the middle the sphenoparietal sinus. meningeal artery, which is • The veins lie lateral to the commonly damaged in head arteries. injuries.
  • 23. Arachnoid Mater  Delicate, impermeable & avascular membrane covering the brain  Lying between Pia mater (internally) & dura Mater(externally)  Separated from dura mater by a potential space, the subdural space (filled by a film of fluid)  Separated from pia mater by the subarachnoid space (filled with CSF)  The outer and inner surfaces covered with flattened mesothelial cells
  • 25. Arachnoid mater Arachnoid projects into venous sinuses - sites for CSF diffuses into bloodstream Arachnoid granulations Arachnoid mater Arachnoid villi Subarachnoid space Subdural space
  • 26. SUBDURAL SPACE : • Superior cerebral Superior cerebral veins beneath arachnoid veins, traverse the subdural space to reach the superior sagittal sinus and its lacunae
  • 27. * Dura Arachnoid Subdural haematoma
  • 28. Subarachnoid Space (SP) :  Relatively narrow over the surface of cerebral hemisphere, but sometimes becomes much wider in areas at the base of the brain, the widest space is called subarachnoid cisterns  The cisterna cerebellomedularis lies between inferior surface of the cerebellum and roof of 4th ventricle  The cisterna interpeduncularis lies between 2 cerebral hemispheres. All the cisternae are in free communication with one another & with the remainder of subarachnoid space
  • 29. Superior cistern Chiasmatic cistern Interpeduncular cistern Pontine Cerebellomedullary cistern cistern Median sagittal section to show the subarachnoid cisterns & circulation of CSF
  • 30. Pia mater Arachnoid Dura * Subarachnoid haemorrage
  • 31. Pia Mater • Pia Mater is a vascular membrane covered by mesothelial cells. • Closely invests the brain, covering the gyri, descending into the deepest sulci & closely applied to the cortical surface.
  • 32. Pia mater Pia mater
  • 33. Pia Mater  It extends out over the cranial nerves & fuses with their epineurium  The cerebral arteries entering the substance of the brain, carry a sheath of pia mater with them  The pia mater forms the TELA CHOROIDAE .  The tela choroidae fuse with ependyma to form the choroid plexus  Choroid plexus forms CSF
  • 34. Choroid plexus of lateral ventricle Ependyma Pia mater of tela choroidae Choroid plexus of 3rd ventricle Coronal section of the interventricular foramen showing the choroid plexus of 3rd & lateral ventricles
  • 35. Read About The Venous Blood Sinuses
  • 37. OBJECTIVES • Illustrate and describe the ventricles. • Describe the structure of the ventricles. • Illustrate and describe the cerebrospinal fluid (CSF) formation, absorption and circulation.
  • 38. VENTRICLES(Ventricular System) • A ventricle is an internal cavity of the brain. Within the brain, which is filled with cerebrospinal fluid(CSF). • The ventricular system is composed of two lateral ventricles and two midline ventricles( third and fourth ventricles).
  • 39. VENTRICLES(Ventricular System) • The chambers are connected to allow the flow of cerebrospinal fluid via two interventricular foramen (referred to as the foramen of Monro) and the cerebral aqueduct (referred to as the aqueduct of Sylvius).
  • 40. Lateral ventricle Interventricular foramen (Monro) Cerebral aqueduct Fourth ventricle Third ventricle Central canal of medulla oblongata & spinal cord Lateral view to show the ventricular system of the CNS
  • 41. VENTRICLES(Ventricular System) CONSISTS OF : 1) Lateral ventricle 2) Third ventricle 3) Fourth ventricle 4) Central canal of the medulla oblongata & spinal cord
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  • 44. Lateral Ventricles • The lateral ventricles are two curved shaped cavities located within the cerebrum. • The lateral ventricles are separated by the septum pellucidum and do not communicate directly
  • 45. Lateral ventricle Parietal lobe Frontal lobe Occipital lobe Temporal lobe
  • 46. Lateral ventricle  C-shaped cavity & may be divided into : 1. Body 2. Anterior 3. Posterior horn Third horn ventricle 4. Inferior horn Fourth ventricle Lateral view of the ventricular cavities of the brain
  • 47. Posterior horn Anterior horn Inferior horn Lateral view to show the ventricular system of the CNS
  • 48. Third ventricle  The third ventricle is a narrow cavity or a slitlike cleft between the 2 thalamus  Communicates ; • Anteriorly with lateral ventricles through interventricular foramina (of monro) • Posteriorly with fourth ventricle through cerebral aqueduct (of sylvius) Posterior view to show the ventricular system of the CNS
  • 49. Third ventricle Parietal lobe Frontal lobe Occipital lobe Temporal lobe
  • 50. Third ventricle ROOF Body of fornix Lateral wall Thalamus Third ventricle FLOOR Hypothalamus Coronal section of the brain (posterior view)
  • 51. Fourth ventricle • The fourth ventricle Is a rhomboid or diamond shaped cavity. • It is a wide and flattened space located just anterior to the cerebellum and posterior to the upper, or superior, half of the medulla oblongata and the pons.
  • 52. Fourth ventricle Fourth ventricle Cerebral aqueduct POSTERIOR ANTERIOR Cerebellum Pons Medulla oblongata (superior half) Central canal (spinal Sagittal section of the 4th ventricle cord)
  • 53. Fourth ventricle Parietal lobe Frontal lobe Occipital lobe Temporal lobe
  • 54. Roof or posterior wall of fourth ventricle : Superior part of the roof ; Superior medullary velum Cerebral aqueduct ANTERIOR POSTERIOR Pons Medulla oblongata (superior half) Inferior part of the roof ; Inferior medullary velum Fig. : Sagittal section of the 4th ventricle
  • 55. Floor or rhomboid fossa of fourth ventricle : Medial sulcus Formed by ; (divides the floor into symmetrical halves) 1. Posterior surface of the pons Medial eminence 2. Cranial ½ Sulcus of the limitans medulla oblongata Facial colliculus Stria Posterior view of the medullaris 4th ventricle Vagal Hypoglossal (strands of nerve triangle triangle fibers)
  • 56. CENTRAL CANAL  Opens superiorly into the fourth ventricle Fourth ventricle Extends ; Inferior ½ of medulla oblongata Central canal Entire (Lined with length of ependyma but no spinal cord choroid plexus in the central canal)
  • 57. CENTRAL CANAL Parietal lobe Frontal lobe Occipital lobe Temporal lobe
  • 60. CHOROID PLEXUS • It is formed by invaginating of vascular pia mater into the Lateral ventricle ventricular cavity • It becomes highly convoluted & produce a spongy-like appearance • It enters the 3rd and 4th ventricles through their roofs, and the lateral ventricles through the choroid fissure Third ventricle • produces cerebrospinal fluid Fourth (CSF) ventricle
  • 61. Pia Mater Choroid BODY OF Plexus of Cavity Of FORNIX The Lateral Lateral Ventricle Ventricle CORPUS CALLOSUM CN Pia Mater of Ependyma Tela THALAMUS Choroidae Cavity Of Choroid Third Plexus of Ventricle The Third Ventricle Blood supply derives from choroidal branches of the internal carotid & basilar arteries Coronal section of the cavities of the lateral and 3rd ventricles
  • 62. Arachnoid mater Pia mater Ependyma Cavity of fourth ventricle CEREBELLUM Choroid plexus of the fourth ventricle •T shaped, vertical part is double • Horizontal part extends into lateral recesses of each ventricle (foramina of Luskha) • Blood supply ; posterior inferior cerebellar arteries
  • 63. What is cerebrospinal fluid (CSF) ? • Clear, colorless fluid • Produced by the choroid plexus • Found in the :  Ventricles of the brain  Subarachnoid space (between Arachnoid + Pia mater) around the brain & spinal cord • The pressure of the CSF is kept remarkably constant. • Based on the Monro-Kellie doctrine : • “Volume of BLOOD, CSF & BRAIN at any time must be relatively constant”
  • 64. Physical characteristics and composition of the CSF Appearance Clear and colourless Volume 130 ml Rate of production 0.5 ml/min Pressure 60-150 mm of water Composition protein 15-45 mg/100 ml glucose 50-85 mg/ 100 ml chloride 720-750 mg/100 ml No. of cells 0-3 lymphocytes/cu mm
  • 65. Function of the CSF : 1. Cushions & protects the CNS from trauma 2. Provides mechanical buoyancy & support for the brain 3. Serves as a reservoir & assists in the regulation of the contents of the skull 4. Nourishes the CNS 5. Removes metabolites from the CNS 6. Serves as a pathway for pineal secretions to reach the pituitary gland
  • 66. Sites of formation : 1. Choroid plexus of the ventricle cavities, mostly is formed in the LATERAL VENTRICLES 2. Some originate from the ependymal cells lining the ventricles 3. Some from the brain substances through perivascular spaces Movement of CSF inside the ventricle is controlled by the: 1. Pulsation of the artery in the choroid plexus 2. By the aid of the cilia & microvilli of the ependymal cells
  • 67. 5 Superiorly = lateral aspect of Choroid plexus of each cerebral 1 the lateral ventricle hemisphere 2 3 Choroid plexus of 3.2 the 3rd ventricle 3.1 Choroid plexus of the 4th ventricle Inferiorly = subarachnoid 4 space around the brain & spinal cord
  • 68. cerebrospinal fluid (CSF) • The CSF is formed in the lateral ventricles escapes by the foramen of monro into the third ventricle • From the third ventricle by the aqueduct into the fourth ventricle. • Then from the fourth ventricle the fluid is poured into the subarachnoid spaces through the medial foramen of majendie and the two lateral foramina of luschka. • There is no evidence that functional communications between the cerebral ventricles and the subarachnoid spaces exist in any region except from the fourth ventricle.
  • 69. Site of formation Choroid plexus of the lateral ventricle 1. Lateral ventricle Superiorly Interventricular foramina Superiorly 2. Third ventricle Cerebral aqueduct Absorbed Absorbed 3. Fourth ventricle 3.2 Lateral 3.2 Lateral foramina foramina (Luschka) (Luschka) 3.1 Median foramen (Magendie) 4. Subarachnoid space Inferiorly
  • 70. Circulation of CSF in subarachnoid space : Superior cistern Chiasmatic cistern Median Interpeduncular foramen of cistern 4th ventricle Pontine Cerebellomedullary cistern cistern Median sagittal section to show the subarachnoid cisterns & circulation of CSF
  • 71. Factors that facilitate the flow of CSF in subarachnoid space ; 1. Pulsation of the cerebral & spinal arteries 2. Movements of the vertebral column 3. Respiration & coughing 4. Changing of the positions
  • 72. Absorption of CSF into dural venous sinuses • Main sites - arachnoid villi (project into dural venous sinuses, especially, superior sagittal sinus) • Arachnoid villi are covered by endothelium of the venous sinus • Arachnoid villi tend to be grouped together & form elevations known as arachnoid granulations • CSF pressure >> the pressure in the sinus • The rate of absorption of CSF through the arachnoid villi controls the CSF pressure
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  • 75. CLINICAL APPLICATION Hydrocephalus • The term hydrocephalus is derived from the Greek words "hydro" meaning water and "cephalus" meaning head. • It is excessive accumulation of fluid in the brain.
  • 76.
  • 77. BLOOD SUPPLY OF THE BRAIN
  • 78. OBJECTIVES • Illustrate and describe the formation of the circle of willis • Describe the blood supply of the brain – Arterial supply – Venous drainage
  • 79. Blood Supply of The Brain • The brain receives it arterial supply from two pairs of vessels, the vertebral and internal carotid arteries which are interconnected in the cranial cavity to produce an arterial circle (of Willis).
  • 81. Internal Carotid Artery • Begins – bifurcation of Com Carotid A • Perforates base of skull – carotid canal • Enters middle cranial fossa beside dorsum sellae • In the cavernous sinus – Horizontal • Emerge out – medial side of Ant clinoid process – perforates dura & arachnoid mater – enters subarachnoid space • Turns posteriorly – below optic nerve • Turns upward – lateral to optic chiasma • Now is under anterior perforated susbtance • Divides – into ANTERIOR & MIDDLE cerebral arteries
  • 82. Middle cerebral Posterior artery Anterior cerebral communicating artery artery Internal carotid artery in cavernous sinus Posterior cerebral artery Internal carotid artery Basilar artery In temporal bone External carotid artery Vertebral artery Common carotid artery
  • 83. Vertebral Artery • Branch of first part of subclavian A • Passes – foramen transvesarium C6 – C1 • Enters through foramen magnum – perforates dura & arachnoid mater – enters subarachnoid space • Turns upward, forward, medially – medulla oblongata • Lower border of pons – joins opposite side – BASILAR artery
  • 84. Middle cerebral Posterior artery Anterior cerebral communicating artery artery Internal carotid artery in cavernous sinus Posterior cerebral artery Internal carotid artery Basilar artery In temporal bone External carotid artery Vertebral artery Common carotid artery
  • 85. Blood Supply of The Brain • VERTEBRAL • INTERNAL CAROTID – Basilar – Middle cerebral – Posterior cerebral artery – Anterior cerebral – Anterior communicating artery – Posterior communicating artery CIRCLE OF WILLIS
  • 86. Branches of :- • VERTEBRAL • INTERNAL CAROTID – Basilar – ACA – PCA – MCA – Pontine – Ophthalmic – Labyrinthine – Ant ComA – Ant Inf CA – Post Com A – Sup cerebellar – Choroidal – Choroidal
  • 87. • CEREBRAL (ICA) • CRANIAL (VERT) – Ophthalmic – Meningeal – Post Communicating – Post Spinal – Choroidal – Ant Spinal – Ant Cerebral – Post Inf Cerebellar • Cortical – Medullary • Central • (BASILAR) • Communicates with – Ant Comm Art – Pontine – Post Cerebral – Labyrinthine – Mid Cerebral – Ant Inf Cerebellar • Cortical – Sup Cerebellar • Central – Post Cerebral • Cortical • Central • Choroidal
  • 88. Circle of Willis • Interpeduncular fossa – base of brain • Anastomosis – 2 internal carotid arteries – 2 vertebral arteries • In the subarachnoid space
  • 90.
  • 91. Anterior communicating Anterior cerebral artery artery Internal Middle cerebral carotid artery artery Posterior communicating artery Sup cerebellar A Posterior cerebral artery Basilar A Ant Inf cerebellar A Post Inf cerebellar A Vertebral arteries
  • 92. Anterior cerebral artery Middle cerebral artery Posterior cerebral artery
  • 93. Central sulcus Superior parietal Superior frontal gyrus lobule Frontal pole Parieto- occipital sulcus Frontal pole Anterior cerebral artery
  • 94. ANTERIOR CEREBRAL ARTERY LOBE AREA FRONTAL Motor – lower limb and perineum - LOBE pericentral lobule PARIETAL Sensory – lower limb and perineum - LOBE paracentral lobule
  • 95. Anterior cerebral artery & anterior communicating artery Lentiform nucleus lentiform Caudate nucleus Internal capsule Internal capsule caudate (ANT) Hypothalamus (ANT)
  • 96. Temporal pole Middle cerebral artery Central branches
  • 97. Central branches Lateral striate arteries Medial striate Left middle Right middle arteries cerebral artery cerebral artery
  • 98. MIDDLE CEREBRAL ARTERY LOBE AREA FRONTAL Motor – except for paracentral lobule Motor speech – esp left side PARIETAL Sensory – except for paracentral lobule Sensory speech TEMPORAL Auditory
  • 99. Middle cerebral artery & anterior choroidal artery Lentiform nucleus lentiform Internal Caudate nucleus capsule caudate Internal capsule (ANT & POST)
  • 100. Inferior temporal gyrus Posterior cerebral artery Inferior temporal gyrus
  • 101. POSTERIOR CEREBRAL ARTERY LOBE AREA OCCIPITAL Visual TEMPORAL Olfactory
  • 102. Posterior cerebral artery & posterior communicating artery Hypothalamus Thalamus (ANT) Internal capsule thalamus Cerebral peduncle Cerebral peduncle
  • 103. Posterior lateral arteries Thalamus (POST) Geniculate bodies thalamus Cerebral peduncle Lateral Geniculate bodies Cerebral peduncle
  • 104. ARTERIES to specific brain areas Corpus striatum Middle & lateral Anterior & striate Middle cerebral Internal capsule artery Thalamus PComA, basilar, PCA Midbrain PCA, supCerebellarA, basilar Pons Basilar, Ant, inf, supCerebellarA, Medulla Vertebral, ASA,PSA,PICA, basilar oblongata Cerebellum supCerebellar, AICA,PICA
  • 105. VENOUS DRAINAGE of THE BRAIN • EXTERNAL • INTERNAL • SPECIFIC – Superior – Thalamo – Midbrain – Pons cerebral striate – Medulla – Superficial oblongata middle – choroidal – cerebellum cerebral – Deep middle cerebral
  • 106. Superior cerebral Superior Sagittal sinus Superior Superficial Sagittal sinus Internal Middle cerebral cerebral Transverse Great sinus cerebral Straight sinus Inferior Sagittal sinus Occipital sinus basal
  • 107. Superior Superior anastomotic V Superior cerebral Sagittal sinus Inferior anastomotic V Superficial Middle cerebral Transverse sinus
  • 108. Superior Sagittal Inferior sinus Sagittal sinus Internal cerebral Great cerebral Straight sinus Site of junction with transverse sinus Occipital sinus basal
  • 109.
  • 110. EXTERNAL CEREBRAL VEIN VEIN AREA DRAINS INTO Superior Superior sagittal cerebral Lateral surface of sinus Superficial cerebral Cavernous sinus middle hemisphere cerebral Deep middle Insula Joined by ant cerebral cerebral & striate- basal vein Sup anas V Superior sagittal sinus Inf anas V Inferior sagittal sinus
  • 111. INTERNAL CEREBRAL VEIN VEIN AREA DRAINS INTO Thalamostriate Basal ganglia, Internal cerebral thalamus, vein - great Choroidal internal cerebral vein – capsule,Tela straight sinus choroidae of 3rd ventricle,hippo DURAL VENOUS campus SINUS
  • 112. VEIN of specific areas Midbrain Basal, great cerebral Pons Basal, cerebellar Medulla oblongata Anterior & posterior spinal Cerebellum Great cerebral
  • 113. Great cerebral Superior cerebral vein vein Superior sagittal sinus Straight sinus Inferior sagittal sinus Middle cerebral vein Medial aspect of Confluence of hemisphere Cavernous sinus sinus Superior Inferior petrosal petrosal sinus sinus Transverse sinus (R & L) IntJugular IntJugular vein vein Sigmoid sinus (R & L)
  • 114. Inferior sagittal Superior sagittal sinus Falx cerebri sinus Tentorium cerebelli Superior petrosal sinus * Confluence of sinus Straight Inferior sinus Sigmoid Transverse petrosal sinus sinus sinus
  • 115. Cavernous sinus Superior petrosal sinus Inferior petrosal sinus Jugular foramen Sigmoid sinus Straight sinus Transverse sinus Superiorsa gittal sinus Confluence of sinus
  • 116. Cavernous sinus • Lateral to body of sphenoid bone • Connected to opposite – intercavernous S • Receives blood – Middle cerebral V • Drains into – Int Jugular V –via Inf petrosal sinus – Transverse S – via Sup petrosal S • Dural Venous sinuses – emissary veins – extracranial V
  • 117. CLINICAL APPLICATION • Stroke or cerebrovascular accident:- – Blockage in the artery – cerebral infarction • Carotid artery • Basilar artery – Bleeding within the brain – intracerebral haemorrhage • Aneurysm • Subarachnoid haemorrhage • Intracerebral haemorrhage - hypertension – Damages one side of the body - contralateral
  • 118. CVA – due to blockage
  • 119. CVA – due to haemorrhage