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Cell & Molecular
Biology
Basic
Chemistry
Chapter 2
Chapter 2
Atoms
The smallest
constituent of matter that
has chemical properties.
Protons
Neutrons
Electrons
Atomic Number
Atomic Weight
Figure 2-7 Essential Cell Biology (© Garland Science 2010)
Figure 2-7 Essential Cell Biology (© Garland Science 2010)
Chemical
Bonds
The Octet Rule
Na?Cl?
H?O?
K?O?     Mg?Cl?
         Mg?Br?
         C?O?
         C?S? Ca?
         Cl?
NaCl
H2O
K2O    MgCl2
       MgBr2
       CO2 / CO
       CS2
       CaCl2
Ionic Bonds
Figure 2-8 Essential Cell Biology (© Garland Science 2010)
Ionic Compounds
or Salts
Covalent Bonds
Figure 2-10 Essential Cell Biology (© Garland Science 2010)
Molecules
Figure 2-11 Essential Cell Biology (© Garland Science 2010)
Polar Covalent Bonds
Figure 2-12 Essential Cell Biology (© Garland Science 2010)
Hydrogen Bonds
Hydrophilic
Molecules
Hydrophobic
Molecules
Electrostatic
Interactions
Figure 2-13 Essential Cell Biology (© Garland Science 2010)
Hydrogen Bonds
A hydrogen bond is the attractive
interaction of a hydrogen atom with an
electronegative atom, such as nitrogen,
oxygen or fluorine, that comes from
another molecule or chemical group.


                   http://en.wikipedia.org/wiki/
                   Hydrogen_bond
Acids and Bases
2H2O    OH-         +    H3   O +

Water   Hydroxide       Hydronium Ion
pH
pH = -log [H+]
Pure Water
[H+] = 0.0000001 M
     = 10 -7 M

pH = 7
M = moles / liter
1 mole = 6.022 x   1023
        atoms or molecules
Lemon Juice
[H+] = 0.01 M
     = 10 -2 M

pH = 2
Figure 2-14 Essential Cell Biology (© Garland Science 2010)
Biological
Macromolecules
Functional Groups
Polysaccharides
Figure 2-16 Essential Cell Biology (© Garland Science 2010)
Monosaccharides
Glucose

Galactose

Fructose
Disaccharides
Figure 2-17 Essential Cell Biology (© Garland Science 2010)
Maltose

Sucrose

Lactose
energy storage
in plants


Starch
      {  amylose


         amylopectin
energy storage
in animals


Glycogen
structure
for plants


Cellulose
structure
in animals


Chitin
Lipids
Figure 2-18 Essential Cell Biology (© Garland Science 2010)
Figure 2-19 Essential Cell Biology (© Garland Science 2010)
Figure 2-20 Essential Cell Biology (© Garland Science 2010)
Nucleic Acids
Nucleotides
Proteins
Figure 2-21 Essential Cell Biology (© Garland Science 2010)
Figure 2-22 Essential Cell Biology (© Garland Science 2010)
Basic biochemistry
Basic biochemistry

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Basic biochemistry