avrilcoghlan

bioinformatics pairwise sequence alignment differential expression deseq rna-seq bioconductor genomes human genome genome sequence sequencing dna sequence homology paralogs homologs orthologs sequence homologs similarity versus homology sequence alignment alignment significance sequence database searches homology searching blast clustal multiple sequence alignment the smith waterman algorithm substitution matrices blosum needleman-wunsch alignment dotplots sequence comparison hidden markov models hmms