GASTROINTESTINALNI TUMORI KLINIČKOPATOLOŠKA I IMUNOHISTOHEMIJSKA STUDIJA 30 MEZENHIMALNIH TUMORA
Autor: Ivana Obradović
Mentor: Mr sci. med. dr Mirjana Ćuk, patolog
1. Gastrointestinalni tumori kliničkopatološka i imunohistohemijska studija 30 mezenhimalnih tumora Autor :Ivana Obradović Mentor:Mr sci. med. dr Mirjana Ćuk UNIVERZITET U ISTOČNOM SARAJEVU MEDICINSKI FAKULTET FOČA
The major histologic patterns of GIST are spindle cell and epithelioid. GIST with a spindle cell morphology often will appear syncytial while clear cell borders are common in epithelioid GIST. Gastric GIST are often of spindle cell morphology, with the epithelioid GIST often historically misclassified as myoblastomas. GIST of the small intestine are primarily of spindle cell morphology. A salient feature of small intestine GIST, especially those of lower risk, is the presence of aggregates of collagen fibers known as skeinoid fibers. In contrast, epithelioid GIST of the small intestine are generally of high risk. Spindle cell morphologies dominate GIST at other sites.